The Center for Human Movement Science - UNC Chapel Hill

Recovery of Paretic Lower Extremity Loading and Weight Transfer Abilities in Individuals Who Are Post-Stroke

Vicki Stemmons Mercer, PT, Ph.D., James Cavanaugh, PT, NCS, Karen McCulloch, MS, PT, NCS, Michael Lee, M.D.

Stroke is a leading cause of serious, long-term disability in the United States. About 4,400,000 stroke survivors are alive today, the majority of whom are older adults. Data from the Framingham Heart Study indicate that 72% of the people who have a stroke in a given year are over 65 years of age. Stroke also is one of the most expensive medical conditions in the United States. Postacute rehabilitation services for patients who have had a stroke account for 44% of all Medicare dollars spent on inpatient rehabilitation and about half of all inpatient rehabilitation charges financed by Medicare. Seventy-three percent of patients who have had a stroke receive some form of postacute rehabilitation care.
Individuals with hemiparesis following a stroke often have difficulty accepting and bearing weight on the paretic (weak) lower extremity. As a result, these individuals commonly exhibit asymmetry in standing and during ambulation, with a greater proportion of body weight distributed on the nonparetic limb than on the paretic limb. Although improved ability to transfer weight and to load the paretic lower extremity is one of the main goals of rehabilitation training for patients with hemiparesis, no investigators have described the time course of change in these abilities following stroke. In addition, scientific evidence for the functional significance of weight transfer and paretic limb loading abilities is limited. Although rehabilitation professionals often assume that lower extremity motor impairments such as weakness are directly related to limitations in functional abilities, the presence or strength of such relationships is largely unknown.
Improved understanding of the contributions of the paretic lower extremity to performance of basic functional tasks will enable rehabilitation professionals to make more informed decisions with respect to intervention design, discharge planning, and program evaluation. Current clinical measures of lower extremity impairment may not capture improved ability to use the paretic lower extremity in functional contexts, so that paretic limb contributions to improvements in functional task performance may be overlooked. In our project, laboratory measures of paretic lower extremity loading and weight transfer abilities are being used to monitor very precisely the changes in these abilities that occur during the first six months of post-stroke recovery. This information, along with the results of analyses of the relationships among various measures of impairment, functional limitation, and disability, will aid clinicians in determining expected outcomes for locomotor function and physical disability.
The long-term research goals are to 1) identify a battery of clinical measures of lower extremity motor impairment that are predictive of functional limitation and disability in individuals recovering from stroke, and 2) use this clinical battery to examine the effectiveness of specific practice conditions and techniques in improving paretic lower extremity loading and weight transfer abilities. Attainment of the latter goal ultimately will require multi-center randomized controlled trials to test the effects of practice variables such as external vs. internal focus of attention, frequency and intensity of practice sessions, and use of biofeedback.