Research Interests
The Boettiger lab studies the problem of addiction from a cognitive perspective. We are interested in determining how certain cognitive processes differ in people with a personal or family history of addiction. We are also interested in determining the cognitive effects of addiction treatments and the brain mechanisms of such effects. Our ultimate goal is to make discoveries that improve treatment and prevention of this common and debilitating neurobehavioral disorder.
Our techniques include combining discrete cognitive tasks in human subjects with neuroimaging, pharmacology, physiological monitoring, and genetics.
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Recent Publications
Click here for a full list of publications from PubMed
Boettiger CA, Mitchell JM, Tavares VC, Robertson M, Joslyn G, D'Esposito M, Fields HL. Immediate reward bias in humans: fronto-parietal networks and a role for the catechol-O-methyltransferase 158(Val/Val) genotype. J Neurosci. 2007 Dec 26;27(52):14383-91.
Mitchell JM, Tavares VC, Fields HL, D'Esposito M, Boettiger CA. Endogenous opioid blockade and impulsive responding in alcoholics and healthy controls. Neuropsychopharmacology. 2007 Feb;32(2):439-49.
Mitchell JM, Fields HL, D'Esposito M, Boettiger CA. Impulsive responding in alcoholics. Alcohol Clin Exp Res. 2005 Dec;29(12):2158-69.
Boettiger CA, D'Esposito M. Frontal networks for learning and executing arbitrary stimulus-response associations. J Neurosci. 2005 Mar 9;25(10):2723-32.
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Bowles Center for Alcohol Studies at the University of North Carolina at Chapel Hill