The Center's research into the causes and mechanisms of addiction provides tomorrow's best hope for improved treatments and, ultimately, finding a reliable cure. Our researchers investigate the mechanisms of alcohol tolerance, dependence and withdrawal, as well as damage to the brain, liver, and fetus. We are developing more compounds to be used, alongside standard therapies, to alleviate withdrawal and reduce relapse. The interaction of genetics and environment are studied to better understand the causes of addiction. Physicians conduct clinical trials to evaluate treatments and bridge the gap between research and practice. Center researchers have developed new scientific techniques and protocols in the field of addiction medicine. Better diagnostic tools for physicians and therapists are emerging through Center research.