Josephine M. Johns, Ph.D.

Associate ProfessorJohns
Department of Psychiatry
Bowles Center for Alcohol Studies

Office | 424 Taylor Hall
Email | jjohns@med.unc.edu
Lab Website | Behav Pharm/Toxicology, Teratology & Neuroendocrinology
Current Biographical Sketch |pdf

Research Interests

In our laboratory, we study the effects of drugs of abuse, particularly psychostimulants, on maternal behavior and aggression and how prenatal exposure to drugs alters the behavioral and biological development of offspring in a rodent model. Our research techniques range from behavioral to molecular, which allows us in collaboration with other scientists, to examine these issues from many different perspectives. We also collaborate on human research projects focusing on the endocrine determinants of social/maternal behavior, particularly following drug use. The interaction between oxytocin and drugs of abuse as it relates to these effects plays a prominent role in our work. Our recent projects have also included studies using an alcohol/nicotine combined gestational treatment model to examine effects on maternal behavior, offspring alcohol preference and oxytocin system changes.

Recent Publications

Click here for a full list of publications from PubMed

Effects of prenatal cocaine exposure on early postnatal rodent brain structure and diffusion properties  McMurray MS, Oguz I, Rumple AM, Paniagua B, Styner MA, Johns JMNeurotoxicol Teratol. 2015 Jan-Feb;47:80-8. doi: 10.1016/j.ntt.2014.11.007. PMID:25459688

Translational analysis of effects of prenatal cocaine exposure on human infant cries and rat pup ultrasonic vocalizations.  Zeskind PS, McMurray MS, Cox Lippard ET, Grewen KM, Garber KA, Johns JMPLoS One. 2014 Oct 22;9(10):e110349. doi: 10.1371/journal.pone.0110349. PMID:25338015

Prenatal cocaine effects on brain structure in early infancy.  Grewen K, Burchinal M, Vachet C, Gouttard S, Gilmore JH, Lin W, Johns J, Elam M, Gerig G. Neuroimage. 2014 Nov 1;101:114-23. doi: 10.1016/j.neuroimage.2014.06.070 PMID:24999039

Effect of prenatal cocaine on early postnatal thermoregulation and ultrasonic vocalization production.  McMurray MS, Zeskind PS, Meiners SM, Garber KA, Tien H, Johns JMFront Psychol. 2013 Nov 26;4:882. doi: 10.3389/fpsyg.2013.00882. PMID:24324452

3-dimensional diffusion tensor imaging (DTI) atlas of the rat brain.  Rumple A, McMurray M, Johns J, Lauder J, Makam P, Radcliffe M, Oguz I. PLoS One. 2013 Jul 5;8(7):e67334. doi: 10.1371/journal.pone.0067334. PMID:23861758

 
 
 
 

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