Faculty & Research

C.J. Malanga, M.D., Ph.D.

Associate Professor
Department of Neurology and Bowles Center for Alcohol Studies

Office | Neuroscience Research Bldg (NSRB) 6109-C

Email | malangacj@neurology.unc.edu

Website | Developmental Neuropharmacology

Research Interests

  • Physiology and pharmacology of the basal ganglia
  • Neurobiology of motivation and reward
  • Effects of early exposure to drugs of abuse on brain and behavioral development
  • Cellular electrophysiology
  • Behavioral and developmental neuroscience
  • Drug abuse neurobiology

Clinical Interests

  • Movement disorders in children
  • Consequences of prenatal exposure to drugs of abuse

Center Line Articles

Recent Publications

Pathway-specific dopaminergic deficits in a mouse model of Angleman syndrome. Riday, TT., Dankoski, E., Krouse, MC., Fish, EW., Walsh, PL., Han, JE., Hodge, CW., Wightman, RM., Philpot, BD. and Malanga, CJ.  Journal of Clinical Investigation 2012 (In Press).

Mephedrone (4-methylmethcathinone) and intracranial self-stimulation in C57BL/6J mice: comparison to cocaine. Robinson, JE., Agoglia, AE., Fish, EW., Krouse, MC. and Malanga, CJ.  Behavioral Brain Research 2012 234(1):76-81.

The rewarding and locomotor-sensitizing effects of repeated cocaine administration are distinct and separable in mice. Riday, TT., Kosofsky, BE. and Malanga, CJ. Neuropharmacology 2012 62(4):1858-66.

Orexin-1 receptor antagonism does not reduce the rewarding potency of cocaine in Swiss-Webster mice. Riday, TT., Fish, EW., Robinson, JE., Jarrett, TM., McGuigan MM. and Malanga, CJ. Brain Research 2012 Jan 11;1431:53-61.

Intracranial self-stimulation in FAST and SLOW mice: effects of alcohol and cocaine.  Fish, EW., Robinson, JE., Krouse, MC., Hodge, CW., Reed, C., Phillips, TJ. and Malanga, CJ.  Psychopharmacology 2012 220(4):719-30

Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism.  Robinson, JE., Fish, EW., Krouse, MC., Thorsell, A., Heilig, M. and Malanga, CJ., Psychopharmacology 2012 220(1):215-24