Transgenic and Knockout Rat Services

The Animal Models Core offers a full range of rat genetic modification services including pronuclear microinjection for production of transgenic rats using plasmid or BAC transgenes and production of knockout/knockin rats by injection of CRISPR/Cas9 nucleases.

Genetically Engineered Rat Services

The availability of new tools for genetic modification of rats is leading many researchers to reconsider rats as a model of choice. The Animal Models Core offers a full range of rat genetic engineering services including

  • Production of transgenic rats using plasmid or BAC transgenes
  • Production of knockout rats by injection of CRISPR/Cas9 nucleases
  • Production of knockin rats or conditional knockout rats by injection of CRISPR/Cas9 nucleases
  • Production and validation of CRISPR/Cas9 nucleases for rat genome modification
  • BAC recombineering, plasmid cloning, etc. to support rat projects
  • Mutation screening, rat genotyping, and rat breeding services

Contact us for more information on options and pricing.