Women's Health Study


whs 1

The purpose of this study is to demonstrate the feasibility and safety of performing longitudinal evaluations of sexual assault survivors who receive post-assault SANE (Sexual Assault Nurse Examiner) care. Data collected will provide important information regarding the recovery process after sexual assault. One finding shows that µ-Opioid Receptor Gene A118G Polymorphism Predicts pain recovery after sexual assault. The data will also provide important information concerning the experiences of sexual assault survivors with law enforcement, SANE nurses, and other medical providers. This information will be used to improve the care of sexual assault survivors. SANE programs WHS FINDINGSparticipating in the Women’s Health Study Network include all major SANE care centers in North Carolina, as well as SANE programs in Alabama, Colorado, Kentucky, Maryland, Michigan, Minnesota, New Mexico, Oklahoma, Pennsylvania, Washington DC, Wisconsin, and Texas. This project is funded through NC TRaCs, and the Department of Anesthesiology. Dr. McLean is PI of this study.

Status: in progress

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Related Publications, Abstracts, and Presentations

Refereed Publications

  1. Ulirsch JC, Ballina LE, Soward AC, Rossi C, Hauda WE, Holbrook D, Wheeler R, Foley KA, Batts J, Collette R, Goodman E, McLean SA. Pain and somatic symptoms are sequelae of sexual assault: results of a prospective longitudinal study. Eur J Pain. 18(4):559-66, 2014. PMID: 24019249
  2. Ballina LE, Ulirsch JC, Soward AC, Rossi C, Rotolo S, Linnstaedt SD, Heafner T, Foley KA, Batts J, Collette R, Holbrook D, Zelman S, McLean SA. µ-Opioid Receptor Gene A118G Polymorphism Predicts pain recovery after sexual assault. J Pain 14(2):165-71, 2013. PMID: 23260451
  3. Orrey D, Soward A, Rotolo S, Rossi C, Roane BM, Csontos E, Casto T, Rauch SAM, Liberzon I, McLean SA. Psychological characteristics associated with pain severity in the early aftermath of sexual assault [abstract]. The J Pain, 11 (4), S1-S104, S12, (121).
  4. Soward AC, Orrey DC, Rotolo S, Rossi C, Roane BM, Csontos E, Casto T, Wheeler B, Rauch S, Slade G, McLean SA. Incidence and distribution of pain symptoms after sexual assault [abstract]. The J Pain, 11 (4), S1-S104, S6, (145).
  5. McLean SA, Soward AC, Ballina LE, Rossi C, Rotolo S, Wheeler R, Foley KA, Batts J, Casto T, Collette R, Holbrook D, Goodman E, Rauch SA, Liberzon I. Acute severe pain is a common consequence of sexual assault. J Pain 13(8):436-41, 2012. PMID: 22698980

Published Abstracts

  1. Keku A, Battles S, Liu A, Soward A, D’Anza T, Bell K, Galloway L, Nouhan P, Groat J, Gieger-Sedgwick A, Ho J, Jarvis K, McLean SA. Design, Implementation, and Initial Results from the Women’s Health Study. Presented at the Annual Meeting of the American Pain Society, Austin, TX, 2016.
  2. Linnstaedt SD, Wu A, Zimny E, Lewandowski C, Hendry PL, Damiron K, Pearson C, Velilla MA, Jones J, Swor R, Domeier R, McLean SA. Sex-dependent expression of microRNA-19b predicts chronic widespread pain and posttraumatic stress disorder development following trauma exposure. Presented at the Annual Meeting of the American Pain Society, Austin, TX, 2016.
  3. Murray CT, Ulirsch J, Soward A, Rossi C, Rotolo S, Wheeler R, Foley K, Batts J, Collette R, Holbrook D, Goodman E, Csontos E, McLean SA. Most sexual assault survivors with new moderate or severe pain do not receive medical care in the initial six weeks after sexual assault [abstract]. J Pain, 14 (4), S32, (#227). Presented at the Annual Meeting of the American Pain Society, New Orleans, LA, May 2013.
  4. Soward A, Ulirsch J, Liberzon I, Rossi C, Rotolo S, Wheeler R, Batts J, Casto T, Collette R, Holbrook D Goodman E,  Csontos E, Rausch SAM,  Diatchenko L, McLean SA. Catechol O-Methyltransferase Haplotype Predicts Posttraumatic Stress Disorder Symptom Severity Six Weeks after Sexual Assault. Presented at the Annual Meeting of the Society of Biological Psychiatry, Philadelphia, PA, May 2012 and at the Annual Meeting of the Society of Academic Emergency Medicine, Chicago, IL, May 2012.
  5. McLean SA, Soward AC, Rotolo S, Rossi C, Whittington K, Rauch SAM, Jackson C, Zelman S, Foley K, Batts J, Liberzon I. New moderate or severe pain is common after sexual assault. Presented at the Annual Meeting of the Society of Biological Psychiatry, San Francisco, CA, 2011.
  6. Soward AC, Whittington K, Rossi C, Rotolo S, Wheeler R, Foley K, Batts J, Casto T, Collette R, Holbrook D, Goodman E, Harney K, Csontos E, Rauch SAM, Liberzon I, McLean SA. Moderate or severe pain is common six weeks after sexual assault. Presented at the Annual Meeting of the American Pain Society, Austin, TX, 2011 and the Annual Meeting of the SAEM, Boston, MA, 2011.
  7. Westphal W, Soward AC, Rossi C, Rotolo S, Heafner T, Foley K, Batts J, Casto T, Collette R, Holbrook D, Goodman E, Harney K, Csontos E, Rauch SAM, Liberzon I, McLean SA. Severe pain is common but rarely treated in the immediate aftermath of sexual assault. Presented at the Annual Meeting of the American Pain Society, Austin, TX, 2011.
  8. Orrey D, Soward A, Rotolo S, Rossi C, Roane BM, Csontos E, Casto T, Rauch SAM, Liberzon I, McLean SA. Psychological characteristics associated with pain severity in the early aftermath of sexual assault. Presented at the annual meeting of the American Pain Society, Baltimore, MD, 2010.
  9. Soward AC, Orrey DC, Rotolo S, Rossi C, Roane BM, Csontos E, Casto T, Wheeler B, Rauch S, Slade G, McLean SA. Incidence and distribution of pain symptoms after sexual assault. Presented at the annual meeting of the American Pain Society, Baltimore, MD, 2010.