Sancar Lab Journal Covers

Sancar lab finds final pieces to the circadian clock puzzle
Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.
Sancar lab manuscript selected as "Paper of the Week" by JBC
The paper titled "Mechanism of Photosignaling by Drosophila Cryptochrome: Role of the Redox Status of the Flavin Chromophore" appears in the February 21, 2014 print edition of The Journal of Biological Chemistry.
Sancar Lab Journal Covers
Sancar lab featured on "In This Issue" of PNAS, published on November 15, 2011
Exposure to UV radiation triggers DNA lesions that can lead to skin cancer, the most common type of cancer in the United States. Previous studies in mice have shown that levels of a protein called XPA, involved in repairing UV-induced DNA lesions, waxes and wanes with the time of day. Shobhan Gaddameedhi et al. found that the protein's level and activity in mouse skin cells are at their lowest at 4 AM and their highest at 4PM.
Sancar lab featured on the cover of PNAS
Sancar lab featured on the cover of JBC published on July 22, 2011
On the JBC Cover: The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism's physiology and behavior.
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