"3D Super-resolution Fluorescence Microscopy"

Dr. Bewersdorf is a Research Scientist with the Jackson Laboratory in Maine.  His research studies biological systems as both three-dimensional (3D) and dynamic.  Visualizing the 3D structure and dynamics at the molecular scale is a current and critical need in biomedical research.  In his group, they are developing and applying new fluorescence (far-field) microscopy techniques with spatial and/or temporal resolutions far exceeding current technology. His laboratory houses the only 4Pi Microscope in the United States, which provides the highest 3D resolution currently commercially available in fluorescence microscopy. They are currently working on several biological efforts, including the characterization of the dendritic spines of neurons in unprecedented detail. They are also researching histone distribution and signaling response to double-strand breaks of DNA in the cell nucleus. Looking ahead, they are in the process of developing several novel microscopy techniques that will go beyond the 3D imaging capabilities of our 4Pi Microscope, creating the microscopes for tomorrow's biological research.

To learn more, please visit his website: research.jax.org/faculty/joerg_bewersdorf.html.

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