"Comprehensive Metabolic Profiling for Understanding Obesity and Diabetes Mechanisms"

Dr. Newgard is a W. David and Sarah W. Stedman Distinguished Professor of Pharmacology and Cancer Biology at Duke University.  His laboratory focuses on understanding metabolic regulatory mechanisms and the application of this knowledge for gaining insights into chronic conditions and diseases such as obesity and diabetes.  Key projects in the lab include: 1) Molecular and biochemical mechanisms of fuel-mediated insulin secretion and their impairment in obesity and diabetes; 2) Mechanisms of pancreatic beta-cell growth and survival; 3) Regulation of glucose and lipid metabolism in liver; 4) Mechanisms by which metabolic alterations in liver affect peripheral (e.g muscle) fuel metabolism. 

In his role as Director of the Sarah W. Stedman Nutrition and Metabolism Center, Dr. Newgard has also formed a clinical research team that is applying comprehensive metabolic and biomarker profiling to obese humans as they lose weight by eight different interventions that are available on the Duke campus or in the surrounding community.

To learn more, please visit his website: http://pharmacology.mc.duke.edu/faculty/newgard.htm.

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