Conference Program


Wednesday, October 13 - Friday, October 15, 2010
The Carolina Inn - Chapel Hill, North Carolina

Organizing Chairs: Leslie V. Parise and Nigel Mackman


Wednesday, October 13

6:30 – 8:30pm:        Reception, Old Well Room


Thursday, October 14

7:00 – 8:00 am:       Pre-Registration, Breakfast and Poster Set-up, Hill Ballroom

8:00 – 8:10 am:       Welcome from UNC SOM Executive Dean Marschall Runge, Hill Ballroom

SESSION I - Platelet Cell Biology, Biochemistry & Signaling, Hill Ballroom
Chairs: Deane Mosher and Magdalena Wodnicka

8:10 – 8:40 am:       Susan Smyth, University of Kentucky
                            
"Novel functions of platelets in inflammation"

8:40 – 9:10 am:       Brian Storrie, University of Arkansas
                                    “Making sense of platelet granules: do platelets have only one class of secretory granules?”

9:10 – 9:40 am:       Jun Qin, Cleveland Clinic
                             "Structural basis of integrin alphaIIbbeta3 activation"

9:40 – 10:05 am:      Break

10:05 – 10:35 am:    Sidney Wally Whiteheart, University of Kentucky
                             "The Molecular Basis for Platelet Secretion"

10:35 – 10:50 am:    Short Talk: Zhenyu Li, University of Kentucky

10:50 – 11:05 am:    Short Talk: Mitali Das, Cleveland Clinic (Plow lab)

11:05 – 11:45 am:    Keynote: David Phillips, Portola Pharmaceuticals
                             “From Memphis with drugs: trials and rewards of antithrombotic drug discovery”

12:00 – 2:00 pm:      Lunch, Old Well Room & Poster Viewing, Hill Ballroom

SESSION II - Inflammation & Cardiovascular Disease, Hill Ballroom
Chairs: Debra Newman and Jonathon Homeister

2:00 – 2:30 pm:       Peter Newman, Blood Research Institute of Wisconsin
"Integrin/ITAM connections in platelets"

2:30 – 3:00 pm:       Jerry Ware, University of Arkansas
                             "The Proinflammatory Platelet"

3:00 – 3:30 pm:       Dan Simon, Case Western University
                                    "Transcriptional Profiling of Platelets in Acute MI"

3:30 – 3:55 pm:       Break

3:55 – 4:25 pm:       Julia Brittain, UNC-Chapel Hill
                                    "Erythropoietin and Thrombin Generation in Sickle Cell Disease"

4:25 – 4:55 pm:       Edward Plow, Cleveland Clinic
                             "Orchestration of Integrin Activation"

4:55 – 5:10 pm:       Short Talk: Zachary Fulkerson, University of Kentucky (Smyth lab)

5:10 – 5:25 pm:       Short Talk: Eric Boilard, Laval University

6:15 - 9:00 pm:       Evening at the Morehead Planetarium
                             6:15 pm - Dinner in the Rotunda

                                    7:30 pm - Carolina Skies show in the Star Theater


Friday, October 15

7:30 – 8:30 am:       Breakfast, Hill Ballroom

SESSION III – Platelets & Thrombosis, Hill Ballroom
Chairs: William Fay and Jane Hoover-Plow

8:30 – 9:00 am:       Roy Silverstein, Cleveland Clinic
                                    “Role of cd36 in thrombosis”

9:00 – 9:30 am:       Alisa Wolberg, UNC-Chapel Hill
                                    "Cellular and Soluble Contributions to Clot Formation, Structure, and Stability"

9:30 – 10:00 am:      David Motto, University of Iowa
                             "Disease physiology in a mouse model of TTP"

10:00 – 10:30 am:    Peter Henke, University of Michigan
                                    "The intersection of thrombotic inflammation and vein wall injury"

10:30 – 10:55 am:    Break

10:55 – 11:25 am:    Raj Kasthuri, UNC-Chapel Hill
                             "Tissue factor bearing microparticles: a novel mechanism for thrombosis in heparin induced thrombocytopenia"

11:25 – 11:55 am:    Elliot Rosen, Indiana University
                             "Fibrin Accumulation By a Developing Thrombus May Limit Growth"

11:55 – 12:10 pm:    Short Talk: Marvin Nieman, Case Western University


After the Conference: