Dec 02, 2014
from 11:00 AM to 12:00 PM
|Contact Name||Amanda Chang|
Open to the public
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"Mechanisms of Fat Synthesis and Storage in Lipid Droplets"
Tobias C. Walther, PhD
Professor of Genetics and Complex Disease
Department of Genetics and Complex Disease
Harvard University , Boston, MA
Bio: Dr. Walther received his PhD in biology from the European Molecular Biology Laboratory and Ludwig-Maximilians University in Munich in 2002. Dr. Walther then joined the Department of Biochemistry and Biophysics at the University of California, San Francisco, to complete his post-doctoral studies. After completion of his postdoctoral training, Dr. Walther became Group Leader at the Max Planck Institute of Biochemistry in Martinsried, Germany. In 2010, Dr. Walther relocated his lab from Germany to the United States and was appointed as an Associate Professor of Cell Biology at the Yale School of Medicine. Dr. Walther is now with Harvard School of Public Health as a professor of Genetics & Complex Diseases.
Abstract: Lipids play a crucial and tightly regulated role in cells as the major component of membranes. Neutral lipids, such as triglycerides, are also crucial for both cellular and physiological energy homeostasis. Membrane precursor lipids and energy storage lipids are stored as neutral lipids in cytosolic lipid droplet organelles. We are studying the molecular processes that govern the synthesis of energy storage lipids as well as their storage in and mobilization from lipid droplets. Studies on genetic factors controlling lipid droplet growth and utilization will be presented, as will relevant studies of the physiology of lipid storage.
Hosted by: Saskia Neher