University of North Carolina researchers provide evidence for how the genetic code developed in two distinct stages to help primordial chemicals evolve into cells.
The new experimental assay can help scientists find the precise locations of repair of DNA damage caused by UV radiation and common chemotherapies. The invention could lead to better cancer drugs or improvements in the potency of existing ones.
The 18 members of the QEP steering committee, led by co-chairs Leslie Parise, professor and chair of biochemistry and biophysics, and Kevin Guskiewicz, professor of exercise and sport science and associate dean in the College of Arts and Sciences, will develop the QEP’s focus, implementation and budget before presenting a draft plan to the Provost. One of the major focuses is improvement on science learning.
The program aims to address the fundamental gaps in knowledge surrounding epigenetic regulation, with a long-term goal of developing novel therapeutic approaches towards treating human disease. Learn more about the newly launched UNC Program in Chromatin and Epigenetics!
These findings published by the Bergmeier lab in the Journal of Clinical Investigation could lead to more personalized approaches to controlling platelet activity during heart attacks and other vascular emergencies and diseases.
Brian Strahl along with other scientists at UNC have created a new way to investigate epigenetic mechanisms important in diseases ranging from Alzheimer’s to cancers. Read more about their work published in Developmental Cell.
By deleting the NrCAM gene, scientists have found a potential way to cut back on the neural connections implicated in Autism Spectrum Disorder.
Sixteen years after scientists found the genes that control the circadian clock in all cells, the lab of UNC’s Aziz Sancar, MD, PhD, discovered the mechanisms responsible for keeping the clock in sync.
Congratulations to the Strahl Lab for their recent article "Catalysis-dependent stabilization of Bre1 fine-tunes Histone H2B ubiquitylation to regulation gene transcription" that was published in the August 1, 2014 issue of Genes and Development.
Congratulations to the Swanstrom lab that published an article titled "A fitness bottleneck in HIV-1 transmission" in the July 11, 2014 issue of Science.
For more than 20 years, Sharon Campbell, PhD, has been studying Ras, a protein implicated in 30 percent of all cancers. Now she’s on the hunt for alternative ways to shut the protein down.
Michael Miley, PhD and Ashutosh Tripathy, PhD announced as the new co-directors for the UNC Center for Structural Biology (CSB). CSB has also launched a brand new website.