Dokholyan lab has a cover story in the December 7, 2011 issue of Structure. Dagliyan et al. present a rapid molecular dynamics-based approach to reveal the mechanism of protein-peptide recognition. The authors find that the peptide, rather than the protein, undergoes an induced fit, and that electrostatic interactions guide the peptide toward the binding region.
Congratulations to Dr. Julia Brittain, Research Assistant Professor of Biochemistry & Biophysics, who was recently selected to the Editorial Board for the publication World Journal of Hematology.
Congratulations to Dr. Yue Xiong, Distinguished Professor of Biochemistry & Biophysics, who was elected as a 2012 AAAS fellow.
Congratulations to Dr. Henrik Dohlman, Professor & Vice-Chair of Biochemistry & Biophysics, who was elected as a 2011 AAAS fellow.
Exposure to UV radiation triggers DNA lesions that can lead to skin cancer, the most common type of cancer in the United States. Previous studies in mice have shown that levels of a protein called XPA, involved in repairing UV-induced DNA lesions, waxes and wanes with the time of day. Shobhan Gaddameedhi et al. found that the protein's level and activity in mouse skin cells are at their lowest at 4 AM and their highest at 4PM.
The University of North Carolina at Chapel Hill, Washington University School of Medicine in St. Louis, and Boise State University have been named partners in one of five US centers that will use genetic data to search for proteins that are abnormally made by cancer cells. The partnerships form the new Clinical Proteomic Tumor Analysis Consortium (CPTAC) supported by the National Cancer Institute (NCI).
On the JBC Cover: The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism's physiology and behavior.
Finding published in the July 21, 2011 issue of Science shows that researchers from the UNC School of Medicine have discovered the seventh and eighth bases of DNA.
The award, established in 2007 by the Battle Foundation of Rocky Mount, recognizes exceptional cancer research within UNC's School of Medicine and comes with a $25,000 prize.
This award, established by the Board of Govenors in 1997, acknowledges a lifetime of contributions to a broad range of teaching and learning, particularly mentoring beyond the classroom.
Congratulations to Dr. Leslie Parise, Professor and Chair of Biochemistry & Biophysics, who has been elected to serve on the Public Affairs Advisory Committee of the American Society for Biochemistry and Molecular Biology (ASBMB).
A Funny Thing Happened on the Way to an Antidote...A "failure" leads to success.