Congratulations to Dr. Henrik Dohlman, Professor & Vice-Chair of Biochemistry & Biophysics, who was elected as a 2011 AAAS fellow.
Exposure to UV radiation triggers DNA lesions that can lead to skin cancer, the most common type of cancer in the United States. Previous studies in mice have shown that levels of a protein called XPA, involved in repairing UV-induced DNA lesions, waxes and wanes with the time of day. Shobhan Gaddameedhi et al. found that the protein's level and activity in mouse skin cells are at their lowest at 4 AM and their highest at 4PM.
The University of North Carolina at Chapel Hill, Washington University School of Medicine in St. Louis, and Boise State University have been named partners in one of five US centers that will use genetic data to search for proteins that are abnormally made by cancer cells. The partnerships form the new Clinical Proteomic Tumor Analysis Consortium (CPTAC) supported by the National Cancer Institute (NCI).
On the JBC Cover: The circadian clock is the internal timekeeping molecular system that generates a daily rhythm in an organism's physiology and behavior.
Finding published in the July 21, 2011 issue of Science shows that researchers from the UNC School of Medicine have discovered the seventh and eighth bases of DNA.
The award, established in 2007 by the Battle Foundation of Rocky Mount, recognizes exceptional cancer research within UNC's School of Medicine and comes with a $25,000 prize.
This award, established by the Board of Govenors in 1997, acknowledges a lifetime of contributions to a broad range of teaching and learning, particularly mentoring beyond the classroom.
Congratulations to Dr. Leslie Parise, Professor and Chair of Biochemistry & Biophysics, who has been elected to serve on the Public Affairs Advisory Committee of the American Society for Biochemistry and Molecular Biology (ASBMB).
A Funny Thing Happened on the Way to an Antidote...A "failure" leads to success.
Former Biochemistry & Biophysics doctoral student Andy Hemmert altered the structure of an enzyme so that it will destroy all known nerve agents used in chemical warfare. Now the U.S. Army is testing it.
Congratulations to the Dohlman lab for their paper highlights in both Science & Science Signaling. Dr. Henrik Dohlman is Professor and Vice-Chair of Biochemistry and Biophysics, and a joint Professor of Pharmacology.
It's a gene called DOT1L, and if you don’t have enough of the DOT1L enzyme, you could be at risk for some types of heart disease. These findings by UNC researchers appear in the journal Genes and Development.