Molecular & Cellular Biophysics

Currently the Program in Molecular & Celllular Biophysics has 48 faculty members from 10 departments. Below is a listing of the faculty with a short research statement and the department in which the faulty member belongs.

	M.L. Berkowitz Chemistry Surface hydration; Computational chemistry

	K. Bloom Biology Molecular Biology; Chromosome and Spindle Dynamics

	R.B. Bourret Microbiology Molecular mechanism of signal transduction in bacteria

	S. Campbell Biochemistry and Biophysics Structure/function of signaling proteins; Multi-D NMR

	C.W. Carter Biochemistry and Biophysics Structural basis for enzyme function; X-ray diffraction

	X. Chen Biochemistry and Biophysics Proteomics

	R. E. Cheney Physiology Cellular motor proteins; The myosin superfamily

	E.J. Collins Microbiology and Immunology MHC Complex protein folding; X-ray crystallography

	M.J. Costello Cell Biology and Anatomy Intercellular junctions; Lens Structure; Electron microscopy

	N. Dokholyan Biochemistry and Biophysics Computational Structural Biology

	T. Elston Mathematics Mathematical Modeling

	D. Erie Chemistry Structure of nucleic acid-protein complexes /Transcription regulation

	C. Fecko Chemistry Physical Properties of Biological Systems; Optical Microscopy Techniques

	G.L. Glish Chemistry Mass spectrometry of proteins and biomolecules

	J. Griffith Microbiology Protein/Nucleic Acid Interactions

	K. Hahn Pharmacology Signaling Dynamics

	K. Jacobson Cell Biology and Anatomy Cell locomotion; Membrane dynamics

	M. Jarstfer Medicinal Chemistry Enzyme function, drug-discovery, and biotechnology

	H. Ke Biochemistry and Biophysics X-ray protein crystallography

	B. Kuhlman Biochemistry and Biophysics Protein Design

	D.Lawrence Chemistry Chemical Biology

	A. Lee Medicinal Chemistry Protein, Structure and Dynamics, NMR Spectroscopy

	J. Liu Medicinal Chemistry Principles of heparin sulfate structural organization; Polysaccharide chemistry

	B.R. Lentz Biochemistry and Biophysics Platelet membrane/blood coagulation; Membrane fusion

	S. Lord Chemistry Molecular Details of Fibrinogen and its Role as Substrate to the Protease Thrombin

	W.F. Marzluff Biochemistry and Biophysics RNA structure/RNA-protein interactions

	S. Matson Biology DNA structure; Helicase-catalyzed unwinding of DNA

	G. Meissner Biochemistry and Biophysics Mechanism of excitation-contraction coupling in muscle

	R. Nicholas Pharmacology Structure/Function of extracellular nucleotide receptors

	A. Oldenburg Physics and Astronomy Biophotonics and Biomechanics

	G.J. Pielak Chemistry Protein structure/function using 2-D NMR

	J. Reader Medicine Protein translation system and in particular the molecular evolution of aminoacyl-RNA synthetases and tRNAs; The molecular evolution of nucleic acids

	M. Redinbo Chemistry Macromolecular crystallography of protein-nucleic acid complexes in human disease

	M. Rubinstein Chemistry Polymer theory and computer simulations

	E.D. Salmon Biology Structure/dynamics of microtubule assembly/disassembly

	A. Sancar Biochemistry and Biophysics Structure and function of DNA photolyase

	M. Schoenfisch Chemistry Implantable sensors, biomaterials, and scanning probe microscopy

	D. Siderovski Pharmacology Structure/function of "regulator of G-protein signaling" (RGS) proteins

	K. Slep Biology Cytoskeletal Structure and Dynamics

	J. Snoeyink Computer Science Geographic Information Systems in analysis of protein folding/structure

	J. Sondek Pharmacology Structural basis of signal transduction; X-ray crystallography

	R. Superfine Physics and Astronomy Cell surface structure; Scanning probe microscopy

	N.L. Thompson Chemistry Cell surface immunochemistry; Fluorescence microscopy

	A.E. Tropsha Medicinal Chemistry Rational Drug Design

	K. M. Weeks Chemistry Structure/function of RNA and protein-RNA complexes

	R.V. Wolfenden Biochemistry and Biophysics Enzyme action; Water in biological processes

Details of our training program course requirements and descriptions of faculty interests and description of research facilities may be accessed via the Web (http://biophysics.med.unc.edu) or in our Program Brochure, which can be obtained by contacting: Lisa Phillippie Program in Molecular and Cellular Biophysics CB# 7260, 3024 Genetics Medicine Chapel Hill, NC 27599-7260 (919) 843-9737 or ldh@med.unc.edu Other inquiries can be directed to: Barry R. Lentz, Program Director (919) 966-5384 or uncbrl@med.unc.edu The University of North Carolina at Chapel Hill does not discriminate against applicants, students or employees based on race, color, national origin, religion, sex, age, or handicap. Moreover, the University is open to people of all races and actively seeks in its admissions policy to promote racial and cultural diversity on its campus.

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