CT Systems

Equipment:

Carbon nanotube (CNT) based microCT imaging system

CNT_CT.jpg

The CNT-based, in-vivo, microCT system was built by Dr. Otto Zhou’s lab at the UNC physics Department. The unique feature of this microCT is the carbon nanotube based X-ray source, which offers many attractive features including electronic programmability and fast switching. It is perfect for a mouse lung imaging study.

Sample Studies

  • Lung imaging on genetically engineered mice
  • Cardiac imaging
  • Colon imaging

Main advantages of the system include:

  • System can provide high resolution (<100 mm)
  • Prospective gating for mouse lung or cardiac imaging with much less dose
  • CT X-ray current: 0 – 1.5 mA
  • CT X-ray source energy: 50kVp
  • Focal Spot Size: 93mm x 109 mm
  • 39mm x 39mm FOV
  • Cone beam Feldkamp reconstruction algorithms 

Sample Images:

CNT_CT_Samples1_Icon.jpg  CNT_CT_Samples2_Icon.jpg

GE eXplore CT120

SpeCT

High-performance, high-throughput small animal In Vivo MicroCT scanner designed for high-quality scanning for a wide variety of applications. It is designed to help visualize, quantify, and characterize anatomical parameters in small animals such as mice and rats. Its table design, versatile bed mount and built-in software support allows image registration with other imaging modalities. 

Sample Studies

  • Nasal passage dimensions
  • Contrast enhanced lung imaging
  • Contrast enhanced tumor imaging
  • Skeletal anatomy and morphology
  • Materials testing

Main advantages of the system include:

  • High Ct resolution (up to 25um) with respiratory gating
  • CT X-ray source energy: 70 to 120kV
  • CT X-ray current: 0-50mA
  • Bore diameters 30mm for mouse, 75mm for rat
  • Modified Feldkamp conebeam reconstruction
  • Allows for multiple bed scans for whole body images

SCANCO µCT 40

MicroCTThe SCANCO µCT 40 scanner is a high resolution desktop cone-bean X-ray scanner designed for specimens with a top resolution of of 6 µm. In addition to the high resolution capabilities, it also offers a larger specimen size (36 mm diameter, 8 cm specimen length).   

Sample studies

  • Bone regrowth after injury or implant
  • Multiple dental applications (microfractures, implants, crown effectiveness, anatomy, etc.)
  • Arthritis models
  • Contrast enhanced soft tissue scans (i.e. embryo, cartilage, muscle, etc.)
  • Calcification in human cardiac arteries
  • Bone density loss in calvaria
  • Vascular and alveolar imaging
  • Materials testing

Analysis examples

  • Bone density
  • Bone volume
  • Connective density
  • Trabecular bone variables
  • Cortical bone variables
  • Linear distance measurements

Main advantages of this system include:

  • Highest resolution available at 6 µm (2000 projections per rotation, 2048 x 2048 pixels)
  • Bone density calibrated so perfect for bone or dental study
  • CT X-ray voltage 50-70 kVp
  • CT X-ray current 150 µA
  • No shielding required
  • Detector 2048x252 elements, 24 µm pitch Resolution 6 µm nominal, 9 µm (10% MTF @ 12 mm Ø)
  • Specimen Size up to 38 mm in diameter, 80 mm in length
  • Software offers complete 64-bit imaging solution, online/offline reconstruction, sophisticated 2D/3D evaluation, 3D-visualization/animation, and archiving data

Click here to view this calendar.

Sample Images (click to enlarge):

SCANCO_Samples1_Icon.jpg  SCANCO_Samples2_Icon.jpg