Eosinophilic Esophagitis (EoE) Research Studies

Eosinophilic Esophagitis (EoE) research studies currently enrolling new participants.

Budesonide Versus Fluticasone for Treatment of Eosinophilic Esophagitis (EoE)

Currently enrolling new subjects

Purpose: To determine whether oral viscous budesonide (OVB) or fluticasone metered dose inhaler (MDI) most effectively treats EoE by improving histologic findings and symptoms, which medication provides a more durable treatment response, and whether biomarkers can predict treatment response.
Principal Investigator:
Evan Dellon, MD MPH
Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Visit ClinicalTrials.gov to learn more about this study. Link: Budesonide Versus Fluticasone for Treatment of EoE

Clinicaltrials.gov


Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

CEGIR

Interested participants can join the contact registry through the Rare Diseases Clinical Research Network. Please follow the link: RareDiseasesNetwork.org

Purpose: To learn about eosinophilic gastrointestinal disorders (EGIDs) and support individuals with the disorders by building a network of patients, researchers, and health care professionals.
Principal Investigators: Evan Dellon, MD MPH at UNC. Marc Rothenberg, MD, PhD at Cincinnati Children's Hospital
Sponsor:
Cincinnati Children's Hospital


Risk Factors and Biomarkers for Diagnosis and Treatment of EoE

Currently enrolling by invitation only

Purpose: To learn about eosinophilic esophagitis (EoE) and find a better and less invasive way other than endoscopy to diagnose EoE.
Principal Investigator:
Evan Dellon, MD MPH
Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Visit ClinicalTrials.gov to learn more about this study. Link: Risk Factors and Biomarkers for Diagnosis and Treatment of EoE

Clinicaltrials.gov


UNC Eosinophilic Esophagitis (EoE) Patient Registry

Currently enrolling by invitation only

Purpose: To learn about eosinophilic esophagitis (EoE) in children, adolescents, and adults. 
Principal Investigator:
Evan Dellon, MD MPH
Sponsor:
University of North Carolina at Chapel Hill

Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis

Currently enrolling by invitation only

Purpose: To test RPC4046, an investigational drug in development by Receptos, Inc. for the potential treatment of Eosinophilic Esophagitis (EoE).
Principal Investigator:
Evan Dellon, MD MPH
Sponsor:
Receptos, Inc.

Visit ClinicalTrials.gov to learn more about this study. Link: Dose Ranging Study of RPC4046 in Eosinophilic Esophagitis

Clinicaltrials.gov


Diagnosis and Monitoring of Eosinophilic Esophagitis Using the Cytosponge

Enrollment starts soon

Cytosponge. Source: http://www.mrc-cu.cam.ac.uk/images/Sponge.jpg

Purpose: To assess the safety, acceptability, and accuracy of Cytosponge for diagnosis and monitoring of Eosinophilic Esophagitis (EoE) in comparison to endoscopy with biopsy as the gold standard.
Principal Investigator:
Evan Dellon, MD MPH
Sponsor and Collaborators:
C.U.R.E.D. Foundation, Mayo Clinic, University of Cambridge

Visit clinicaltrials.gov to learn more about Diagnosis and Monitoring of EoE Using Cytosponge

Clinicaltrials.gov


Please contact us for more information regarding any of the above active CEDAS research studies:

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