Caron Lab - Publications

Link to PubMed

Selected Publications:

Wetzel-Strong SE, Li M, Klein KR, Nishikimi T, Caron KM. (2014) Epicardial-derived adrenomedullin drives cardiac hyperplasia during embryogenesis. Dev Dyn, 2014. 243(2): p. 243-56.

Matson BC, Corty RW, Karpinich NO, Murtha AP, Valdar W, Grotegut CA, Caron KM. (2014) Midregional pro-adrenomedullin plasma concentrations are blunted in severe preeclampsia. Placenta, 2014. 35(9): p. 780-3.

Li M, Wetzel-Strong SE, Hua X, Tilley SL, Oswald E, Krummel MF, Caron KM. (2014) Deficiency of RAMP1 attenuates antigen-induced airway hyperresponsiveness in mice. PLoS One, 2014. 9(7): p. e102356.

Lenhart PM, Nguyen T, Wise Am Caron KM, Herring AH, Stuebe AM. (2014) Adrenomedullin signaling pathway polymorphisms and adverse pregnancy outcomes. Am J Perinatol, 2014. 31(4): p. 327-34.

Li M, Schwerbrock NM, Lenhart PM, Fritz-Six KL, Kadmiel M, Christine KS, Kraus DM, Espenshied ST, Willcockson HH, Mack CP, Caron KM.  (2013) Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta. J Clin Invest, 2013. 123(6): p. 2408-20.

Lenhart PM, Broselid S, Barrick CJ, Leeb-Lundberg LM, Caron KM. (2013) G-protein-coupled receptor 30 interacts with receptor activity-modifying protein 3 and confers sex-dependent cardioprotection. J Mol Endocrinol, 2013. 51(1): p. 191-202.

Karpinich NO, Kechele DO, Espenschied ST, Willcockson HH, Fedoriw Y, Caron KM. (2013)  Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis. FASEB J, 2013. 27(2): p. 590-600. 

Karpinich NO, Kechele DO, Espenshied ST, Willcockson HH and Caron KM. (2012) Dosage of adrenomedullin correlates with tumor lymphangiogenesis and distant metastasis. FASEB J. Oct 25. PMID:23099649

Hoopes SL, Willcockson HH, Caron KM. (2012) Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice. PLoS One. 2012;7(9):e45261. doi: 10.1371/journal.pone.0045261. Epub 2012 Sep 17. PMID: 23028890

Wooten D, Lindmark H, Kadmiel K, Willcockson H, Caron KM, Barwell J, Drmota T, Poyner DR. (2012) Receptor Activity Modifying Proteins (RAMPs) interact with the VPAC2 and CRF1 receptors and modulate their function. British J Pharmacol. 2012 Sep 5. doi: 10.1111/j.1476-5381.2012.02202.x. [Epub ahead of print] PMID: 22946657

Arce RM, Caron KM, Barros SP and Offenbacher S. (2012) Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice. Mol Oral Microbiol 2012 Oct;27(5):373-81.

Lenhart PM and Caron KM. (2012) Adrenomedullin Signaling in Pregnancy: From Mouse Models to Clinical Medicine. Trends in Endocrinology & Metabolism 2012 Oct;23(10):524-32. PMID:22425034

Kadmiel M, Fritz-Six KL, Caron KM. (2012) Understanding RAMPs Through Genetically Engineered Mouse Models. Adv Exp Med Biol. 744:49-60.

Barrick D, Dackor R, Nagel E and Caron KM. (2012) Loss of RAMP3 exacerbates hypertension-related cardiac hypertrophy and heart failure in a gender-dependent manner. J Mol. & Cell. Cardiology 52(1):165-174.

Karpinich NO, Hoopes SL, Kechele DO, Lenhart PM and Caron KM. (2011) Adrenomedullin function in vascular endothelial cells: insights from genetic mouse models. Current Hypertension Rev. 7(4):217-227.

Kadmiel M, Fritz-Six K, Pacharne S, Richards G, Skerry T and Caron KM. (2011) Haploinsufficiency of receptor activity modifying protein 2 (Ramp2) causes reduced fertility, hyperprolactinemia, skeletal abnormalities and endocrine dysfunction in mice. Mol Endo (7):1244-53 PMID: 21566080.

Dunworth WP, Caron KM. (2009) G Protein-Coupled Receptors as Potential Drug Targets for Lymphangiogenesis and Lymphatic Vascular Diseases.  Arterioscler Thromb Vasc Biol. 2009

Dunworth WP, Fritz-Six KL, Caron KM. (2008) Adrenomedullin stabilizes the lymphatic endothelial barrier in vitro and in vivo. Peptides. Dec;29(12):2243-9.

Li M, Wu Y, Caron KM. (2008) Haploinsufficiency for adrenomedullin reduces pinopodes and diminishes uterine receptivity in mice. Biol Reprod. Dec;79(6):1169-75.

Fritz-Six KL, Dunworth WP, Li M, Caron KM. (2008) Adrenomedullin signaling is necessary for murine lymphatic vascular development. J Clin Invest. 118(1):40-50.

Gibbons C, Dackor R, Dunworth W, Fritz-Six K, Caron KM. (2007) Receptor activity-modifying proteins: RAMPing up adrenomedullin signaling. Mol Endocrinol. 21(4):783-96.

Li M, Yee D, Magnuson TR, Smithies O, Caron KM. (2006) Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice. J Clin Invest. 116(10):2653-62.

Dackor RT, Fritz-Six K, Dunworth WP, Gibbons CL, Smithies O, Caron KM. (2006) Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol. 26(7):2511-8.