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Martina Gentzsch research published in the Journal of Clinical Investigation Insight

Martina Gentzsch research published in the Journal of Clinical Investigation Insight

In a significant step toward personalized medicine for cystic fibrosis, a minimally-invasive technique shows promise as a fast, inexpensive indicator to help more patients access new treatments.

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Mark Zylka Elected as AAAS Fellow

Mark Zylka Elected as AAAS Fellow

Mark Zylka has been recognized by the world’s largest general scientific society for his contributions to the fields of biological and medical sciences. Election as an AAAS Fellow is an honor bestowed upon AAAS members by their peers. This year 396 members have been awarded this honor by AAAS because of their scientifically or socially distinguished efforts to advance science or its applications. This year’s AAAS Fellows will be formally announced in the AAAS News & Notes section of the journal Science on November 24, 2017. New Fellows will be presented with an official certificate during the 2018 AAAS Annual Meeting in Austin, Texas on February 17.

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Lorenzo Lab research published in PNAS

Lorenzo Lab research published in PNAS

An article by Dr. Damaris Lorenzo in collaboration with her postdoctoral advisor Dr. Vann Bennett at Duke University titled “Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency” was published this week ahead of print in PNAS. In this study, Dr. Lorenzo shows that mice lacking the cytoskeleton-associated protein ankyrin-B only in adipose tissue become obese despite having normal appetite and physical activity levels. Using cellular essays, the study also shows that novel human mutations in the ankyrin-B gene also leads to cell-autonomous adiposity.

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Erica Cloer successfully defends dissertation

Erica Cloer successfully defends dissertation

Congratulations to Erica Cloer for successfully defending her thesis entitled "Molecular mechanisms of patient-derived KEAP1 superbinder mutants".

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Brooke Matson successfully defends dissertation

Brooke Matson successfully defends dissertation

A huge CONGRATULATIONS to Brooke Matson for successfully defending her thesis entitled "Molecular Regulators of Embryo Implantation and Pregnancy". Way to go, Dr. Matson!!

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Welcome our newest CBP Assistant Professor, Dr. Sarah Cohen!

Welcome our newest CBP Assistant Professor, Dr. Sarah Cohen!

Dr. Cohen has developed state-of-the-art, super-resolution spectral imaging technologies to simultaneously label and track the position of 6 different cellular organelles in real time. In doing so, she has characterized a new cell organelle called a lipid droplet. In her future work, she hopes to use these techniques to address how lipid droplets from glia and astrocytes can be used to transfer lipids to neurons. This is an important question because neurons cannot synthesize their own lipids, but yet are dependent on huge amounts of lipids to extend lengthy neuronal processes and regulate membrane turnover at synaptic terminals.

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A warm welcome to our new CBP Faculty, Dr. Graham Diering!

A warm welcome to our new CBP Faculty, Dr. Graham Diering!

Dr. Diering is a neurobiologist and biochemist focused on understanding the different mechanisms that neurons use to sleep. In one process, neurons change their synapses to accommodate the formation of memories. In another simultaneous process, synaptic plasticity supports the conservation of neuronal metabolism and “recharging”—which is critically important for cognition and behavior. Graham uses sophisticated biochemistry and genetic animal model behavior studies to map the neuronal circuits and molecular pathways that underlie these different types of sleep. His work has very important implications for sleep disorders, and particularly those related to neurodevelopmental disorders with aberrant sleep, such as Rhett syndrome and Autism spectrum disorders.

A warm welcome to our new CBP Faculty, Dr. Graham Diering! - Read More…

Caron Lab research featured on the cover of Biology of Reproduction

Caron Lab research featured on the cover of Biology of Reproduction

An article from the lab of Dr. Kathleen Caron titled “Adrenomedullin improves fertility and promotes pinopodes and cell junctions in the peri-implantation endometrium” is featured on the cover of the September 2017 issue of Biology of Reproduction. The cover image, “Pinopode Eclipse,” depicts pinopodes, or uterodomes, which are plasma extravasations of uterine luminal epithelial cells present during the window of implantation in rodents and humans and are thought to enable blastocyst attachment and invasion. Image courtesy of Brooke Matson and Kelsey Quinn.

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Keith Burridge selected as ASCB Fellow

Keith Burridge selected as ASCB Fellow

Congratulations to Dr. Keith Burridge for being selected as a 2017 American Society for Cell Biology Fellow! The ASCB Fellows award recognizes ASCB members who have made outstanding contributions to the field of cell biology and to the community of cell biologists through their service to ASCB. This is an honor bestowed upon Dr. Burridge by his peers in recognition of Keith’s life-time achievements and meritorious efforts to advance cell biology and its applications.

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Ben Major receives the 2017 ACCLAIM Leadership Program Award

Ben Major receives the 2017 ACCLAIM Leadership Program Award

The Academic Career Leadership Academy in Medicine (ACCLAIM) is a UNC School of Medicine one-year program, started in 2012, that provides leadership and career development opportunities to faculty members (ACCLAIM Scholars), with an emphasis on those underrepresented in medicine.

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Deshmukh lab research featured in Vital Signs

Deshmukh lab research featured in Vital Signs

The National Institute on Aging awarded a $2.6-million, five-year grant to UNC’s Mohanish Deshmukh’s lab to explore miR-29, a key molecule that helps mature brain cells avoid death.

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Remembering Dr. Peter Petrusz

Remembering Dr. Peter Petrusz

Long-time faculty member Peter Petrusz was a leader in the study of hormones important for the growth, development, and maintenance of neural structures.

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Gupton Lab paper featured as cover article of MBoC

Gupton Lab paper featured as cover article of MBoC

The axon guidance cue netrin-1 and its receptor DCC promote axon branching in developing cortical neurons. In this study, we detail a novel molecular mechanism by which the brain-enriched E3 ubiquitin ligase TRIM9 orchestrates multimerization of DCC, requisite activation of FAK and Src family kinases, and increases in exocytic vesicle fusion, all during netrin-dependent neuronal morphogenesis. We are the first to show that non-degradative ubiquitination of a receptor alters kinase activation and signaling pathways during morphogenesis.

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Spencer Smith Receives Prestigious Hettleman Prize

Spencer Smith Receives Prestigious Hettleman Prize

Spencer Smith has been selected to receive the 2017 Ruth and Phillip Hettleman Prize for Artistic and Scholarly Achievement. The award is one of the University's most prestigious acknowledgments of faculty excellence. Congratulations Dr. Smith!!

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Spencer Smith featured in Vital Signs

Spencer Smith featured in Vital Signs

The five-year NSF project led by UNC researcher Spencer Smith will develop new imaging systems and technology to explore the brain like never before.

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