Bhat lab findings on axonal membrane protein Neurofascin published in the journal Neuron

January 2011 - The protein called Neurofascin 186, which accumulates in the membranes of axons at the nodes of Ranvier, has critical role in nerve impulse conduction

Bhat lab findings on axonal membrane protein Neurofascin published in the journal Neuron click to enlarge Mouse sciatic nerve myelinated axons immunostained against three proteins: Neurofascin 186 at the node of Ranvier (green), Contactin-associated protein at the paranodes (blue) and potassium channels at the juxtaparanodes (red). Image source: Bhat lab.

January 2011 - The Bhat lab describes a key molecular mechanism in nerve fibers that ensures the rapid conductance of nervous system impulses. The findings appear online Jan. 27, 2011 in the journal Neuron.

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Nodes of Ranvier Act as Barriers to Restrict Invasion of Flanking Paranodal Domains in Myelinated Axons. Courtney Thaxton, Anilkumar M. Pillai, Alaine L. Pribisko, Jeffrey L. Dupree, Manzoor A. Bhat 

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