In a paper published in Nature Communications, Janet Berrios, a graduate student in the Philpot lab, discovered that the loss of UBE3A decreases the release of the GABA neurotransmitter and alters reward-seeking behavior in an important neural pathway once presumed to be principally regulated by the dopamine neurotransmitter.
Mark Zylka, PhD, will serve as director and Ben Philpot, PhD, will serve as associate director of the UNC Neuroscience Center at the UNC School of Medicine, effective July 1. William Snider, MD, who has served as the center’s director for nearly 17 years, will step down from his leadership role, but will remain on faculty as professor of neurology, while also continuing his research.
Deshmukh lab discovers a novel role of Dicer in the rapidly dividing cells of the developing brain and brain tumors
In a paper published in Cell Reports, Vijay Swahari, a postdoctoral fellow in Deshmukh lab, identifies how the critical role of Dicer in DNA damage response can be exploited for therapy in aggressive brain tumors like Medulloblastoma.
Postdoctoral fellow Dr. Shalini Menon and graduate student Nicholas Boyer have co-first author paper, "The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance” published in Developmental Cell on Dec 21, 2015. The article was highlighted by a preview penned by Dr. Thomas Pollard. An image from this work, showing growth cones turning was selected for the cover.
Temperance Rowell is a second-year graduate student in the lab of Dr. Robert Tarran.
When Spencer Smith, assistant professor of cell biology and physiology in the School of Medicine who studies the brain, grew frustrated with the lack of resolution provided by traditional microscopes, he and his co-inventor Jeffrey Stirman decided to build his own. The results could unlock some of the brain's greatest mysteries.
The Zylka Lab's research on autism has recently been featured on WRAL, WUNC (NPR), and the UNC Healthcare Newsroom.
The September 15, 2015 issue of Molecular Biology of the Cell has chosen a paper from the Brennwald lab entitled “Structural Basis for Recognition of the Sec4 Rab GTPase by its Effector, the Lgl/Tomosyn homologue, Sro7” as one of its Highlighted Articles. Kelly Watson, a graduate in the lab, was first author on the paper. An image from this work showing a model for the interaction of the Rab GTPase, Sec4 and its effector Sro7 was chosen for the cover.
Kelly Watson successfully defended her thesis on August 6th! Congratulations Dr. Watson!!
Robert Sons successfully defended his thesis on July 14th! Congratulations Dr. Sons!
Ayumi Nakamura is a MD/PhD student in Mohanish Deshmukh's lab.
This briefing was held at the Rayburn House Office Building, Room B338 on Capitol Hill, Thursday, July 9th. Panelists discussed some of the ways researchers are prying open the black box of the brain and will share some important recent discoveries. This briefing was particularly timely in light of the two-year anniversary of the White House Brain Initiative, which is receiving about $200 million in federal funding in fiscal year 2015.
Congratulations to Dr. Petrusz on his retirement! We wish you happiness in your future endeavors!
Liz Haynes successfully defended her thesis on Tuesday, June 23rd! Congratulations Dr. Haynes!!
Caron Lab Postdoctoral Fellow, Reema Davis, has received the MAA Winter 2015 Postdoctoral Fellowship.
Klara Klein successfully defended her thesis during her private defense on May 6th and presented her public defense on May 22nd. Congratulations Dr. Klein!!
Bailey Zwarycz receives an NRSA F31 from the National Institute of Diabetes and Digestive and Kidney Diseases entitled "Determining the relationship between Sox9 and Collagen XVIII in maintaining intestinal stem cell identity".