Potential treatment strategy for Angelman syndrome identified by Philpot, Zylka and Roth
December 2011 - Collaborators Ben Philpot, Mark Zylka and Bryan Roth identify compounds that cause the dormant Ube3a gene to be expressed.
At top, a mouse brain showing flourescent expression of the UBE3A gene, and below, lack of expression when the maternal copy of the gene is missing.
December 2011 - An interdisciplinary team of UNC scientists say they have found a way to “awaken” the paternal allele of Ube3a, which could lead to a potential treatment strategy for Angelman syndrome (AS). Their results were published online by the journal Nature. Read the complete UNC School of Medicine news release >>
Filed under:
Zylka news,
Philpot news
