Kathleen Caron, PhD

Kathleen Caron, PhD

Department Chair
Professor
UNC-Chapel Hill 

6312B MBRB
Campus Box 7545
Chapel Hill, NC 27599-7545
919-966-5215

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Education and Training

Emory University, BS/BA, 1992
Duke University, PhD, 1997
University of North Carolina at Chapel Hill, Postdoctoral, 1997-2003

Areas of Interest

Studies in the Caron Lab are focused on elucidating unique G protein-coupled receptor pathways that are important for the development and function of the cardiovascular system. Using a variety of gene-targeted animal models in conjunction with state-of-the-art in vitro cell biological systems, we have discovered fundamental roles for several secretin- and chemokine-family receptors in cardiovascular development and disease. Much of our recent work has focused on the pivotal roles that RAMPs (receptor activity-modifying proteins) play in controlling receptor function, cellular signaling, and physiology. The importance of the RAMP-receptor interaction is best exemplified by our work centered on the small blood protein, adrenomedullin – a potent lymphangiogenic vasodilator that serves as a strong prognostic indicator for many disease conditions.

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Affliations

Cell Biology and Physiology Curriculum
Department of Genetics
UNC McAllister Heart Institute
Lineberger Comprehensive Cancer Center
Curriculum in Genetics and Molecular Biology
Integrative Vascular Biology Program
Developmental Biology Program