University of North Carolina at Chapel Hill
Departments of Microbiology & Immunology
Professor Immunology, Virology
Fellow, American Association for the Advancement of Science. 2010 IDF Elie Metchnikoff Prize 2010 UNC System "O. Max Gardner" Award. 2009 Alexander Quarles Holladay Medal for Excellence. NC State University Board of Trustees. 2006-2007 Nicholas Appert Award. Institute of Food Technologists. 2007 Sigma Xi Distinguished Lecturer. 2006-2008 Faculty Resource and Development Award. NC State University, College of Agricultural and Life Sciences. 2006 William C. Haines Dairy Science Award. California Dairy Research Foundation. 2006 Bruce P. Wasserman Memorial Lectureship. Rutgers, The State University of New Jersey. 2005 Fellow, American Dairy Science Association. 2004 William C. Frazier Memorial Award for Contributions to Food Microbiology. 2002 Outstanding Achievement Award. University of Minnesota. 2001. Fellow, American Academy of Microbiology. 2001. Fellow, Institute of Food Technologists. 2000. Research and Development Award. Institute of Food Technologists. 1998. Borden Award. American Dairy Science Association. 1996. Gamma Sigma Delta Certificate of Merit. NC State University. 1995 The National Award for Agricultural Excellence. Carolina/Virginia National Agricultural Marketing Association. 1994 Alumni University Research Award. NC State University Alumni Association. 1990 Dairy Research Foundation Award. American Dairy Science Association. 1990 Samuel Cate Prescott Research Award. Institute of Food Technologists. 1989. Nordica International Research Award. American Cultured Dairy Products Institute. 1989. Certificate of Distinguished Scholarly Achievement. NC State University. 1986 Sigma Xi Research Award. NC State University. 1986 Pfizer Award. American Dairy Science Association. 1984
Our research activities have emphasized the development of genetic systems in gram positive lactic acid bacteria and the use of genomic approaches to improve cultures for bioprocessing applications in food. The overall goal of the program is to provide avenues for improvement and diversification of food bioprocessing and preservation systems through genetic investigation and modification of lactic acid bacteria. Our major research contributions have been primarily in five areas. 1. Genomic and comparative genomic analysis of lactic acid bacteria and their bacteriophages. 2. Definition of gene directed mechanisms that protect the dairy lactococci from attack by bacteriophages. 3. Characterization of the biochemical and genetic properties of bacteriocins produced by lactic acid bacteria. 4. Development of cloning and expression vectors (mobilization, expression, integration, secretion) for genetically ill�defined bacteria important in food bioprocessing or probiotic applications. 5. Genetic and physiological studies on intestinal Lactobacillus species to investigate and expand their potential beneficial roles in vivo.
Link to list of publications on PubMed.
University of North Carolina
Chapel Hill NC 27599-7080
(O)919 515 2972