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Core Facility Administration

Information on the offices involved with core facility advocacy, support, and oversight.

Office of Translational Technologies

The Office of Translational Technologies (OTT) provides operational support to the University’s core facilities, and serves as a resource for investigators needing information and access to general and specialized scientific instrumentation and services available from our core facilities.

OTT Services:

  • Assistance with Operational Infrastructure
    OTT assists core facilities deal with a range of operational needs; application process for new recharge service centers as well as rate revisions for existing cores, survey design and distribution which provide valuable feedback to core directors from their client base, and identification of laboratory, information, and financial management systems which may be useful tools for increasing core efficiency.
  • Education and Training
    OTT organizes and assists with educational workshops and forums which focus on introducing core users to new technologies, as well as training and information for core directors.  Offerings in the past have included presentations from industry introducing new technologies, core directors covering available services and techniques, and group talks on specific scientific research areas.
  • Increasing Core Visibility
    OTT strives to increase awareness and usage of our core facilities through promotional materials, website, and events highlighting core facilities.
  • Advocacy
    OTT is engaged in a continuing conversation with Office of Sponsored Research and School of Medicine Office of Research to develop, disseminate and implement policies and guidelines affecting core facilities.

OTT Staff:

 Michael Topal, Ph.D.
Assistant Dean for Core Technologies
School of Medicine
E-mail: michael_topal@med.unc.edu
Phone: (919) 966-8208

Christopher Barker, Ph.D.
Director, Office of Translational Technologies
E-mail: chris_barker@med.unc.edu
Phone: (919) 843-6745

Annabelle Stein
Assistant Director, Office of Translational Technologies
E-mail: abelle@med.unc.edu
Phone: (919) 843-9554

Core Facilities Advocacy Committee (CFAC)

The Core Facilities Advocacy Committee is appointed by and reports to the School of Medicine Vice Dean for Research. The committee is chaired by the Assistant Dean for Core Technologies.

Reviewing the scientific and operational status of cores is a major function of the committee. The committee includes faculty members chosen for their expertise in specific categories of technology and for their interest in strengthening core facilities at UNC. Current categories, each advocating for multiple cores, include 1) Animal Models and Phenotyping, 2) Biochemistry,
3) Clinical/Translational, 4) Genomics and 5) Imaging.  Committee members work directly with core facility directors to evaluate and recommend upgrading of technology and to ensure high-quality services and user satisfaction. The committee reviews requests and makes recommendations for expenditures for core facilities, including the purchase of new equipment.
The role of CFAC includes advising the Vice Dean of Research on equipment needs and funding development of new core facility technologies, space allocation, and the expansion, sunsetting, and consolidation of existing cores. 

 

Cost Analysis and Compliance, Office of Sponsored Research

 The Cost Analysis and Compliance Office performs the institutional review, appproval and oversight function that allows research service center facilities to charge fees for services.

 

Core Facilities

Animal Model Cores

Animal Clinical Chemistry & Gene Expression
Animal Histopathology
Animal Models Core
Animal Studies Facility
BAC Engineering Core Facility
CGBID Gnotobiotic Core
Histology Research Core Facility
In Situ Hybridization Core Facility
Mouse Cardiovascular Models Core
Mutant Mouse Regional Resource Center
Mouse Behavioral Phenotyping Core
NORC Animal Metabolism Phenotyping Core
Oligonucleotide Synthesis
UNC Systems Genetics Core
Xenopus Aquatic Facility
Zebrafish Aquaculture Core Facility

Biochemistry Cores

ADME Mass Spectrometry Center
Biomarker Mass Spectrometry Fac.
Biomolecular NMR Lab
CFAR Immunology Core Lab
CGBID Histology Core
High Throughput Peptide Synthesis and Array Facility
Immunology Core Facility
Macromolecular Crystallography Core Facility
Macromolecular Interactions Facility
MH Proteomics & Mass Spectrometry Facility
Nucleic Acids Core Facility
Pharmacy NMR Facility
Protein Sequence & Peptide Synthesis Facility
R. L. Juliano Structural BioInformatics Core
Systems-Proteomics Center
UNC Metabolomics Laboratory

Clinical Cores

Analytical Chemistry and Pharmacology Core
Biobehavioral Laboratory
Biospecimen Processing Facility
Center for Human Movement Science
Clinical & Translational Research Center
Cytokine Analysis Facility
Human Behavioral Phenotyping Lab.
Research Participant Registry Core
NORC Diet, Physical Activity, and Body Composition Core
NORC Nutritional Biochemistry and Molecular Biology Core
Nutrition Research and Metabolism
Tissue Procurement Facility
Translational Pathology Laboratory
UNC CFAR Clinical Pharmacology & Analytical Chemistry

Genomics Cores

Functional Genomics Core
High Throughput Genomic Sequencing Facility
Human Embryonic Stem Cell Core Facility
Lenti-shRNA Core Facility
Lineberger Genomics and Bioinformatics Core
Mammalian Genotyping Core
RNAi Screening Facility
UNC Microbiome Core Facility
UNC-CH Genome Analysis Facility
Vector Core
Vironomics Core

Imaging Cores

Biomedical Research Imaging Center (BRIC) /Imaging Center
Biomedical Research Imaging Center (BRIC) Image Storage & Analysis
Cell and Developmental Biology Microscopy Imaging Facility
Center for Gastrointestinal Biology and Disease, Imaging Core
CH Analytical and Nanofabrication Lab (CHANL)
Confocal and Multiphoton Imaging Facility
Flow Cytometry
Michael Hooker Microscopy Facility
Microscopy Services Laboratory
Developmental Neuroimaging Lab.

Other Cores

Center for BioInformatics
Cellular Metabolism and Transport Core
NORC Communication for Health Applications and Intervention
NORC Clinical Research Services
ESE Research Design Center
CGBID Biostatistics Core
CGBID Immunotechnologies
Chemistry Dept Electronics Facility
Chemistry Dept Mass Spectrometry Facility
Chemistry Department NMR Facility
Chemistry Dept X-Ray Crystallography Facility
Molecular Genetics Laboratory
Data Mgt & Statistical Analysis
Oral Microbiology Laboratory
Pharmacometrics Core
Retrovirology Core Facility
Tissue Culture Facility