Location: CSB Homepage >SBI Core >Computer Tools

R.L. Juliano Structural Bioinformatics Core Facility (SBI)
SBI Core logo
SBI Director:
Brenda Temple, Ph.D.
mail icon
4062 Genetic Medicine
CB# 7260
tel: +1-919-843-9399

Available Software Packages

The facility offers access to state a variety of software packages for structure visualization, modeling and analysis. Researchers are trained insoftware tools for protein and DNA sequence analysis, protein fold determination, structure
superimposition and comparison, homology modeling, active site identification, mutation effects analysis, and drug docking. Available software packages include SYBYL, Insigtht II, FELIX, QUANTA, spock, VMD, CCP4, AMBER, crystallography or NMR spectroscopy.

structureSequence Analysis

Multiple sequence alignments, phylogenetic analysis, ancestral sequence predictions,
secondary structure predictions, domain prediction, functional residue prediction

Structure Visualization and Analysis

Structure vusualization, electrostatic surfaces, homology modeling, amino acid mutation analysis, solvent accessibility calculations, subunit contact analysis, molecular dynamics calculations, free energies of binding, active side identification, docking of small molecules, figures for grants and publications, molecular movies for presentations.

For more information on what services are available go to General Information.

For examples of current research using our tools, please visit Research Applications.




Copyright © 2009-2014 UNC-CH Center for Structural Biology. All Rights Reserved. For any issues with this site or suggestions, please contact Webmaster.