Autoimmunity of Pemphigus
Research in Dr. Li's laboratory explores the mechanism involved in autoantibody-induced epidermal cell detachment (acantholysis). Current studies are listed below:
- Role of proteases in acantholysis
- Role of apoptosis in acantholysis
- Role of P53 transcription factor in acantholysis
- Role of carbohydrate moieties on desmogleins on autoantibody-induced acantholysis
Dr. Li's research is NIH-funded.