Current Grants

NIH/NHLBI Ammerman (overall PI), Dewalt (R01 PI) 05/01/10-04/30/15

Reducing Disparities in Hypertension with a Practiced-Based Enhanced Care Program.

This is an R01 project embedded within a larger P50 center grant to study health disparities. This grant will study implementation of practice-based strategies to reduce hypertension disparities. This is a 5 year project where community based participatory research methods are used to design and implement a quality improvement program in primary care practices in Eastern North Carolina. The overall goals are to reduce blood pressure levels among patients with poorly controlled hypertension, reduce disparities in blood pressure by race and by literacy, create systems that can sustain these improvements within current primary care practice, and understand the time required by practices to provide enhanced care for hypertension.

 

UNC School of Medicine/CTSA Asher (PI) 7/01/10 – 6/30/13

Curcumin Pharmacokinetics and Tissue Concentrations

This career award will provide protected time, funding, and educational support to investigate the bioavailability of different preparations of curcumin after oral ingestion, as well as biomarkers of effect for curcumin in the bowel.

Becker-Dreps (PI) 9/01/11-8/31/13

NIH-Fogarty International Center International Research Scientist Development Award

The purpose of this grant is to study the effectiveness of the rotavirus vaccine immunization program and childhood diarrhea in Nicaragua.

 

1 R18-HS-19131-01 Donahue (PI), Halladay (Co-I) 08/01/10-07/31/13

Transforming Primary Care Practice in North Carolina

This study aims to describe the process of change in primary care practices participating in North Carolina’s Improving Performance in Practice Program, identify the practice changes most associated with improvement in clinical outcomes, identify environmental factors associated with successful transformation, and measure the cost of transformation.

 

P50 Center Donahue (Co-I) 4/1/10-3/31/15

Centers for Population Health and Health Disparities Program (NHLBI,NCI, OBSSR)

This project will study the effects of a carefully designed practice-based, sustainable, blood pressure management program that specifically addresses factors associated with racial disparities in blood pressure control including those at the individual and practice levels with a goal of reducing racial disparities.

P50 Center Donahue (Co-I) 4/1/10-3/31/15

Centers for Population Health and Health Disparities Program (NHLBI, NCI, OBSSR)

This RCT will enroll a diverse patient population of 300 participants; compare an enhanced lifestyle intervention to a community only intervention to determine its effect on 1) diet quality, physical activity, weight change, and CVD risk factors at 6, 12, 18 and 24 month follow-up and 2) closing the racial and literacy disparities in these outcomes.

 

Fraher (PI), Pathman (Co-I) 7/1/11-6/30-13

Physicians' Foundation An Open Source Model for Projecting Physician Shortages in the United States

 

Goldstein (PI) 7/1/10-6/30/13

Pfizer Pharmaceutical

Establishing and disseminating model hospital smoking cessation programs: from inpatient to outpatient (I2O) settings

Goal to promote development, implementation and dissemination of model inpatient tobacco cessation programs across North Carolina.

North Carolina Department of Health and Human Services.

Outcome Evaluation of the NC Teen Tobacco Use Prevention and Cessation Programs

The North Carolina Department of Health and Human Services works to reduce and prevent tobacco use among youth and young adults in North Carolina through three major Tobacco Initiatives and two media campaigns:

• Teen Tobacco Use Prevention and Cessation Initiative (Teen Initiative) and the Tobacco.Reality.Unfiltered. (TRU) media campaign
• Tobacco-Free Colleges Initiative (Colleges Initiative)
• North Carolina Tobacco Quitline (QuitlineNC) and the “Call it Quits” media campaign

The North Carolina Department of Health and Human Services launched the Teen Initiative in 2003, began funding components of QuitlineNC in 2005, and expanded to the Colleges Initiative in 2006. These comprehensive, evidenced-based state tobacco control programs are a proven method, along with policy initiatives, to reduce tobacco consumption among youth and adults.

 

Gourlay (PI) Grant #K23 RR024685 7/07-6/13

Selective Screening for Osteoporosis in Younger Postmenopausal Women

This is a 5-year cross-sectional study of osteoporosis risk assessment and screening in postmenopausal women aged 50 to 64 years.

 

Grant #R03 AR055734 Gourlay (PI) 9/08-6/13

FSH as a Biomarker of Bone Strength in Younger Postmenopausal Women

This is a 3-year cross-sectional study to test whether follicle stimulating hormone might be used to screen for low bone density in postmenopausal women aged 50 to 64 years.

 

U1CRH03714-04-00 Pathman (supplement PI); Holmes (parent grant PI) 6/1/10-8/31/13

Federal Office of Rural Health Policy, HRSA

Study of the Flux in Federal and State Health Care Loan Repayment Programs

 

#2-T32-HP14001-16 Pathman (PI) 7/1/08-6/30/13

Bureau of Health Professions, HRSA

NRSA Primary Care Research Fellowship

This grant prepares physician-fellows from the specialties of family practice, general internal medicine and general pediatrics for careers as primary care researchers. Two to three years of training is provided, during which fellows earn Masters or Doctorates and complete several research projects under the mentorship of accomplished UNC faculty.

 

Sloane (PI) 1/1/11-12/31/13

Improving Oral Hygiene in Nursing Homes. Research and Demonstration Grant: FutureCare of North Carolina. Zimmerman (Co-PI).

 

Sloane (PI) 9/1/10 - 8/31/13

Randomized Trial of a University-AAA State Partnership to Link Primary Care Physicians and Aging Services Providers in the Support of Persons with Alzheimer's Disease and Related Disorders. Alzheimer's Innovation Grant #90A10038, U.S. Agency on Aging. $504.250

 

R01 HL098604-01 Viera (PI) 6/1/10-5/31/14

National Heart Lung and Blood Institute Reproducibility and Clinical Implications of Masked Hypertension

The primary purpose of this project is to examine the degree to which masked hypertension (normal office blood pressure with elevated out-of-office blood pressure) is reproducible, thereby providing important information that will help guide evidence based recommendations for out-of-office blood pressure monitoring strategies.

 

Recent Grants

NIH/NCI/ UNC SPORE in Gastrointestinal Cancer Asher (PI) 7/01/10 – 6/30/11

Curcumin Chemoprevention of Colorectal Neoplasia: A Phase II Biomarker Study

This study will investigate the effect of multidose curcumin on biological markers relevant to colorectal cancer in patients with and without colonic adenoma.

 

Becker-Dreps (PI)

Thrasher Early Career Award 2/1/09-7/31/11

Merck Investigator Initiated Grant Program 7/1/09-12/31/11

The purpose of these two grants are to study the effectiveness of the rotavirus vaccine immunization program and childhood diarrhea in Nicaragua.

 

1-R21-AG030166 Daaleman (PI) 08/01/09-07/31/11

National Institute on Aging

A Feasibility Study to Improve Older Patient-Physician Communication

The goal of this study is to implement, assess, and disseminate a novel health information technology intervention that enhances quality patient-physician communication.

UNC Vulnerable Population Care Service Daaleman (Program Director) 01/01/10-12/31/11

AccessCare

The goal of this Medicare Demonstration Project is to implement the principles of the Patient-Centered Medical Home, such as access and coordination of care, currently delivered by a network accountable care organization, to enhance care for vulnerable patients, such as nursing home residents and community-dwelling patients with serious mental illness.

 

Goldstein (PI), 7/1/10-6/30/11

Lineberger Cancer Center Smoking cessation to cancer patients

Goal to promote development, implementation and dissemination of model tobacco cessation programs at Cancer Centers.

 

Goldstein (PI), 03/15/10-01/31/12

NIH ARRA Stimulus Funds

Expanding and enhancing tobacco cessation services through the North Carolina Tobacco Use Quit Line (QuitlineNC)

The goal of this study is to promote tobacco cessation quitline services to Medicaid and Uninsured smokers.

 

UNC American Recovery and Reinvestment Act (ARRA)/ North Carolina Department of Health and Human Services, Division of Public Health

American Recovery and Reinvestment Act: Communities Putting Prevention to Work. Supplemental Component III

The primary goal of the Communities Putting Prevention to Work Supplemental Component III grant is to significantly expand and enhance tobacco cessation services through the North Carolina Tobacco Use Quit Line (QuitlineNC). The North Carolina Department of Health and Human Service will use this funding to pay for services and outreach to uninsured and Medicaid-insured tobacco users. The tobacco Prevention and Evaluation Program evaluates the quit rate and satisfaction of the uninsured & low income caller and evaluates the effectiveness of a pilot project providing Nicotine Replacement Therapy (NRT)to tobacco user clients admitted in the Walter B Jones Drug and Alcohol Treatment Facility.

 

Pathman (PI) 7/1/07-6/30/11

Office of the Dean, UNC School of Medicine

Initiative to Identify and Eliminate Racial-Ethnic Disparities within UNC Health Care

This project will use all possible clinical and administrative data with the UNC Health Care System to identify differences in care received by the System’s African American, Hispanic and White patients. QI-type efforts will be undertaken with departments and services to address identified care differences.

 

HHSH25034002T Pathman (PI) 10/1/10-9/30/11

Health Resources and Services Administration Evaluating Retention in BCRS Programs

This project will survey clinician participants, and administrators, of the National Health Service Corps in 2010, 2005 and 1998 to document changes in the retention of the NHSC’s clinicians over the past decade.

 

Sloane (PI)

Blue-White Light Therapy for Circadian Sleep Disorders in Alzheimer's Disease, Research Grant # R21 AT004500-01A1: National Center for Complementary and Alternative Medicine, National Institutes of Health. 9/30/08 - 6/30/12. Margaret Figuiero, PhD (Co-PI), Rensselaer Polytechnic Institute (NY). $297,230.

 

Sloane (PI)

Prescribing of Antibiotics by Primary Care Clinicians in Long-Term Care Facilities. Tak Order Contract #HHSA290200710014I: U.S. Agency for HealthCare Research and Quality, 8/24/09 - 8/23/12. Sheryl Zimmerman, PhD (Co-PI). $624,992.

 

Sloane (PI)

Alzheimers Memory Center. Grant: Duke Endowment #6076-SP, 7/1/08-12/31/12. Dr. Dan Kaufer (Co-PI) UNC Department of Neurology. $540,491.