Rachel Bailey

Rachel Bailey, PhD


Postdoctoral Researcher

 

 

 

 


Contact Info

UNC Gene Therapy Center
CB# 7352
Chapel Hill, NC 27599

Office: 5111 Thurston Bowles
Phone:  919-962-2566
Fax: 
CV | Email

Research Interests

 Dr. Rachel Bailey is a post-doctoral research associate in the laboratory of Dr. Steven Gray.  Dr. Bailey is working on a gene therapy for Giant Axonal Neuropathy (GAN), a rare pediatric neurodegenerative disorder that is characterized by progressive sensory and motor neuropathy, which is caused by homozygous loss-of function mutations in the GAN gene.  Children with GAN first present with gait impairment as young as 3 with worsening motor and sensory function over time and ultimate mortality during the second or third decades as there currently is no effective treatment for this disorder.  Dr. Bailey’s work involves the pathological characterization of GAN disease models and the optimization of GAN gene replacement therapy via viral vector delivery in these models.  Findings from this work will be coupled to a proposed Phase I human clinical trial for the use of viral gene therapy to treat GAN. 

Before joining Dr. Gray’s laboratory, Dr. Bailey received her B.S. in Bioinformatics and Molecular Biology/Biology from Rensselaer Polytechnic Institute, worked as a research technician at the Medical University of South Carolina and at the Mayo Clinic Jacksonville and earned her Ph.D. from the University of Florida.  As a graduate student in the laboratory of Dr. Jada Lewis, Dr. Bailey’s main project investigated a putative link between LRRK2 and tau - proteins that are critically involved in the neurodegenerative diseases Parkinson’s disease and tauopathy, respectively.