News

UNC Genetics News

Shawn Ahmed's group reports on a novel mechanism of gene silencing in Caenorhabditis elegans, termed "multigenerational RNAe"

Shawn Ahmed's group reports on a novel mechanism of gene silencing in Caenorhabditis elegans, termed "multigenerational RNAe"

The title of the article, published in PNAS, is "Lack of pairing during meiosis triggers multigenerational transgene silencing in Caenorhabditis elegans." Co-first authors are Luciana Leopold, a graduate student in the Curriculum in Genetics and Molecular Biology, and Bree Heestand, a postdoctoral fellow in Shawn's lab.

Shawn Ahmed's group reports on a novel mechanism of gene silencing in Caenorhabditis elegans, termed "multigenerational RNAe" - Read More…

Fernando Pardo-Manuel de Villena named one of two inaugural Oliver Smithies Investigators

Fernando Pardo-Manuel de Villena named one of two inaugural Oliver Smithies Investigators

Oliver Smithies Investigator Award recipients are selected based on their sustained excellence in their chosen disciplines, their international reputation as a leader in their fields and the impact of their research within the medical and scientific communities.

Fernando Pardo-Manuel de Villena named one of two inaugural Oliver Smithies Investigators - Read More…

Sara Selitsky has first-authored a paper published in Scientific Reports (Nature's open access journal).

Sara Selitsky has first-authored a paper published in Scientific Reports (Nature's open access journal).

The title of the paper is "Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C." Sara is a BCB graduate student who is co-mentored by Praveen Sethupathy and Stan Lemon (Department of Medicine).

Sara Selitsky has first-authored a paper published in Scientific Reports (Nature's open access journal). - Read More…

 Article by Terry Furey's group highlighted in Genetics

Article by Terry Furey's group highlighted in Genetics

Matt Weiser, a graduate student in Terry's lab, is first author on the paper, entitled "Novel Distal eQTL Analysis Demonstrates Effect of Population Genetic Architecture on Detecting and Interpreting Associations."

Article by Terry Furey's group highlighted in Genetics - Read More…

Shawn Ahmed and colleagues publish a paper in PNAS demonstrating a novel function of two C. elegans RNA interference proteins

Shawn Ahmed and colleagues publish a paper in PNAS demonstrating a novel function of two C. elegans RNA interference proteins

Shawn and Eric Miska at the University of Cambridge are senior authors on the paper, and Shawn's former postdoc, Aisa Sakaguchi, and former graduate student, Matt Simon, as co-first authors with Peter Sarkies from Dr. Miska's lab.

Shawn Ahmed and colleagues publish a paper in PNAS demonstrating a novel function of two C. elegans RNA interference proteins - Read More…

Jim Evans and Chuck Perou are featured in a Special Section on Breast Cancer in Science

Jim Evans and Chuck Perou are featured in a Special Section on Breast Cancer in Science

Evans and Perou are quoted regarding the risks of reporting germline mutations in numerous genes implicated in rare forms of hereditary predispositions to breast cancer.

Jim Evans and Chuck Perou are featured in a Special Section on Breast Cancer in Science - Read More…

Samir Kelada and Praveen Sethupathy Coauthor New Article in PLoS Pathogens

Samir Kelada and Praveen Sethupathy Coauthor New Article in PLoS Pathogens

In collaboration with groups at three other institutions, they identified different miRNAs that are critical "regulatory hubs" in the immune response to the parasites Leishmania major and Schistosoma mansoni.

Samir Kelada and Praveen Sethupathy Coauthor New Article in PLoS Pathogens - Read More…

Chuck Perou Receives 2013 Battle Cancer Research Award

Chuck Perou Receives 2013 Battle Cancer Research Award

Chuck has been honored with the 2013 Hyman L. Battle Distinguished Cancer Research Award in recognition of his accomplishments in cancer research.

Chuck Perou Receives 2013 Battle Cancer Research Award - Read More…

New Publications from Praveen Sethupathy's Lab

New Publications from Praveen Sethupathy's Lab

A research article highlights a method for prioritizing variants in miRNAs by their functional significance. Two Thematic Reviews are included in a special section of the Journal of Lipid Research.

New Publications from Praveen Sethupathy's Lab - Read More…

Jim Evans publishes Viewpoint article in JAMA

Jim Evans publishes Viewpoint article in JAMA

The article by Jim Evans discusses the importance of the involvement of knowledgeable health care providers in communicating complex genomic information to patients and research subjects.

Jim Evans publishes Viewpoint article in JAMA - Read More…

Chuck Perou named as a finalist for the Triangle Business Journal's 2013 "Health Care Heroes" award

Chuck Perou named as a finalist for the Triangle Business Journal's 2013 "Health Care Heroes" award

Triangle Business Journal on Tuesday unveiled 29 finalists for its 2013 Health Care Heroes Awards. Chuck and colleagues have also recently published an article in The Oncologist

Chuck Perou named as a finalist for the Triangle Business Journal's 2013 "Health Care Heroes" award - Read More…

Karen Mohlke has paper published in Nature Genetics

Karen Mohlke has paper published in Nature Genetics

Karen Mohlke is corresponding author on a paper reporting low-frequency variants in three new genes associated with abnormal insulin production or processing.

Karen Mohlke has paper published in Nature Genetics - Read More…

New mouse model to visualize tumor growth

New mouse model to visualize tumor growth

Ned Sharpless and colleagues have developed a mouse model that makes it possible to visualize tumor growth by means of a "knocked-in" p16 gene linked to a luciferase reporter.

New mouse model to visualize tumor growth - Read More…

Diabetes investigation in rats makes editor's pick in APS journal.

Diabetes investigation in rats makes editor's pick in APS journal.

An investigation into diabetes-related outcomes in a rat model, with senior author William Valdar, PhD, assistant professor of genetics at UNC, and first author Leah Solberg Woods, PhD, from the Medical College of Wisconsin, has made the editor's pick in this month's Physiological Genomics, a journal of the American Physiological Society.

Diabetes investigation in rats makes editor's pick in APS journal. - Read More…

Praveen Sethupathy is Co-Senior Author of a paper highlighted by the journal Hepatology.

Praveen Sethupathy is Co-Senior Author of a paper highlighted by the journal Hepatology.

Title of the paper is "MicroRNA-27b is a regulatory hub in lipid metabolism and is altered in dyslipidemia," published in the February 2013 issue.

Praveen Sethupathy is Co-Senior Author of a paper highlighted by the journal Hepatology. - Read More…