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Department of Genetics faculty and collaborators published eleven papers between August 20 and September 2, 2017.

Genetic architecture of atherosclerosis dissected by QTL analyses in three F2 intercrosses of apolipoprotein E-null mice on C57BL6/J, DBA/2J and 129S6/SvEvTac backgrounds.

Makhanova N, Morgan AP, Kayashima Y, Makhanov A, Hiller S, Zhilicheva S, Xu L, Pardo-Manuel de Villena F, Maeda N.

PLoS One. 2017 Aug 24;12(8):e0182882. doi: 10.1371/journal.pone.0182882. eCollection 2017.

PMID: 28837567

p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics.

Hafner A, Stewart-Ornstein J, Purvis JE, Forrester WC, Bulyk ML, Lahav G.

Nat Struct Mol Biol. 2017 Aug 21. doi: 10.1038/nsmb.3452. [Epub ahead of print]

PMID: 28825732

Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer.

Taylor NA, Vick SC, Iglesia MD, Brickey WJ, Midkiff BR, McKinnon KP, Reisdorf S, Anders CK, Carey LA, Parker JS, Perou CM, Vincent BG, Serody JS.

J Clin Invest. 2017 Aug 21. pii: 90499. doi: 10.1172/JCI90499. [Epub ahead of print]

PMID: 28825599

A Serendipitous Mutation Reveals the Severe Virulence Defect of a Klebsiella pneumoniae fepB Mutant.

Palacios M, Broberg CA, Walker KA, Miller VL.

mSphere. 2017 Aug 23;2(4). pii: e00341-17. doi: 10.1128/mSphere.00341-17. eCollection 2017 Jul-Aug.

PMID: 28861522

Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.

Troester MA, Sun X, Allott EH, Geradts J, Cohen SM, Tse CK, Kirk EL, Thorne LB, Mathews M, Li Y, Hu Z, Robinson WR, Hoadley KA, Olopade OI, Reeder-Hayes KE, Earp HS, Olshan AF, Carey LA, Perou CM.

J Natl Cancer Inst. 2018 Feb 1;110(2). doi: 10.1093/jnci/djx135.

PMID: 28859290

The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases.

Laakso M, Kuusisto J, Stančáková A, Kuulasmaa T, Pajukanta P, Lusis AJ, Collins FS, Mohlke KL, Boehnke M.

J Lipid Res. 2017 Mar;58(3):481-493. doi: 10.1194/jlr.O072629. Epub 2017 Jan 24.

PMID: 28119442

Histone locus regulation by the Drosophila dosage compensation adaptor protein CLAMP.

Rieder LE, Koreski KP, Boltz KA, Kuzu G, Urban JA, Bowman SK, Zeidman A, Jordan WT 3rd, Tolstorukov MY, Marzluff WF, Duronio RJ, Larschan EN.

Genes Dev. 2017 Aug 24. doi: 10.1101/gad.300855.117. [Epub ahead of print]

PMID: 28838946

Identification of Human Papillomavirus Infection in Cancer Tissue by Targeted Next-generation Sequencing.

Montgomery ND, Parker JS, Eberhard DA, Patel NM, Weck KE, Sharpless NE, Hu Z, Hayes DN, Gulley ML.

Appl Immunohistochem Mol Morphol. 2016 Aug;24(7):490-5. doi: 10.1097/PAI.0000000000000215.

PMID: 26371432

Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.

Lickwar CR, Camp JG, Weiser M, Cocchiaro JL, Kingsley DM, Furey TS, Sheikh SZ, Rawls JF.

PLoS Biol. 2017 Aug 29;15(8):e2002054. doi: 10.1371/journal.pbio.2002054. eCollection 2017 Aug.

PMID: 28850571

Fragile X Newborn Screening: Lessons Learned From a Multisite Screening Study.

Bailey DB Jr, Berry-Kravis E, Gane LW, Guarda S, Hagerman R, Powell CM, Tassone F, Wheeler A.

Pediatrics. 2017 Jun;139(Suppl 3):S216-S225. doi: 10.1542/peds.2016-1159H.

PMID: 28814542

EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex.

Lei Y, Kansy BA, Li J, Cong L, Liu Y, Trivedi S, Wen H, Ting JP, Ouyang H, Ferris RL.

Oncogene. 2016 Sep 8;35(36):4698-707. doi: 10.1038/onc.2016.11. Epub 2016 Feb 15.

PMID: 26876213