Department of Genetics faculty and collaborators published fifteen papers during the last two weeks of October 2017.
Xie Y, Liu Y, Valdar W.
Biometrika. 2016 Sep;103(3):493-511. doi: 10.1093/biomet/asw035.
PMID: 29038606
Lipopolysaccharide Potentiates Insulin-Driven Hypoglycemic Shock.
Hagar JA, Edin ML, Lih FB, Thurlow LR, Koller BH, Cairns BA, Zeldin DC, Miao EA.
J Immunol. 2017 Oct 16. pii: ji1700820. doi: 10.4049/jimmunol.1700820. [Epub ahead of print]
PMID: 29038248
Chappell GA, Israel JW, Simon JM, Pott S, Safi A, Eklund K, Sexton KG, Bodnar W, Lieb JD, Crawford GE, Rusyn I, Furey TS.
Environ Health Perspect. 2017 Oct 16;125(10):107006. doi: 10.1289/EHP1937.
PMID: 29038090
A noncanonical function of cGAMP in inflammasome priming and activation.
Swanson KV, Junkins RD, Kurkjian CJ, Holley-Guthrie E, Pendse AA, El Morabiti R, Petrucelli A, Barber GN, Benedict CA, Ting JP.
J Exp Med. 2017 Oct 13. pii: jem.20171749. doi: 10.1084/jem.20171749. [Epub ahead of print]
PMID: 29030458
Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos.
Graff M, Emery LS, Justice AE, Parra E, Below JE, Palmer ND, Gao C, Duan Q, Valladares-Salgado A, Cruz M, Morrison AC, Boerwinkle E, Whitsel EA, Kooperberg C, Reiner A, Li Y, Rodriguez CJ, Talavera GA, Langefeld CD, Wagenknecht LE, Norris JM, Taylor KD, Papanicolaou G, Kenny E, Loos RJF, Chen YI, Laurie C, Sofer T, North KE.
Lipids Health Dis. 2017 Oct 12;16(1):200. doi: 10.1186/s12944-017-0591-6.
PMID: 29025430
A SNP panel and online tool for checking genotype concordance through comparing QR codes.
Du Y, Martin JS, McGee J, Yang Y, Liu EY, Sun Y, Geihs M, Kong X, Zhou EL, Li Y, Huang J.
PLoS One. 2017 Sep 19;12(9):e0182438. doi: 10.1371/journal.pone.0182438. eCollection 2017.
PMID: 28926565
p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics.
Hafner A, Stewart-Ornstein J, Purvis JE, Forrester WC, Bulyk ML, Lahav G.
Nat Struct Mol Biol. 2017 Oct;24(10):840-847. doi: 10.1038/nsmb.3452. Epub 2017 Aug 21.
PMID: 28825732
Richmond-Rakerd LS, Otto JM, Slutske WS, Ehlers CL, Wilhelmsen KC, Gizer IR.
Nicotine Tob Res. 2017 Apr 1;19(4):426-434. doi: 10.1093/ntr/ntw260.
PMID: 27663783
UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.
Shpargel KB, Starmer J, Wang C, Ge K, Magnuson T.
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9046-E9055. doi: 10.1073/pnas.1705011114. Epub 2017 Oct 9.
PMID: 29073101
Reversing SKI-SMAD4-mediated suppression is essential for T<sub>H</sub>17 cell differentiation.
Zhang S, Takaku M, Zou L, Gu AD, Chou WC, Zhang G, Wu B, Kong Q, Thomas SY, Serody JS, Chen X, Xu X, Wade PA, Cook DN, Ting JPY, Wan YY.
Nature. 2017 Oct 25. doi: 10.1038/nature24283. [Epub ahead of print]
PMID: 29072299
Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance.
Rosshart SP, Vassallo BG, Angeletti D, Hutchinson DS, Morgan AP, Takeda K, Hickman HD, McCulloch JA, Badger JH, Ajami NJ, Trinchieri G, Pardo-Manuel de Villena F, Yewdell JW, Rehermann B.
Cell. 2017 Oct 17. pii: S0092-8674(17)31065-6. doi: 10.1016/j.cell.2017.09.016. [Epub ahead of print]
PMID: 29056339
Implication of LRRC4C and DPP6 in neurodevelopmental disorders.
Maussion G, Cruceanu C, Rosenfeld JA, Bell SC, Jollant F, Szatkiewicz J, Collins RL, Hanscom C, Kolobova I, de Champfleur NM, Blumenthal I, Chiang C, Ota V, Hultman C, O’Dushlaine C, McCarroll S, Alda M, Jacquemont S, Ordulu Z, Marshall CR, Carter MT, Shaffer LG, Sklar P, Girirajan S, Morton CC, Gusella JF, Turecki G, Stavropoulos DJ, Sullivan PF, Scherer SW, Talkowski ME, Ernst C.
Am J Med Genet A. 2017 Feb;173(2):395-406. doi: 10.1002/ajmg.a.38021. Epub 2016 Oct 19.
PMID: 27759917
Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, Giulianini F, Boutin TS, Abdellaoui A, Zhao W, Medina-Gomez C, Bartz TM, Trompet S, Lange LA, Raffield L, van der Spek A, Galesloot TE, Proitsi P, Yanek LR, Bielak LF, Payton A, Murgia F, Concas MP, Biino G, Tajuddin SM, Seppälä I, Amin N, Boerwinkle E, Børglum AD, Campbell A, Demerath EW, Demuth I, Faul JD, Ford I, Gialluisi A, Gögele M, Graff M, Hingorani A, Hottenga JJ, Hougaard DM, Hurme MA, Ikram MA, Jylhä M, Kuh D, Ligthart L, Lill CM, Lindenberger U, Lumley T, Mägi R, Marques-Vidal P, Medland SE, Milani L, Nagy R, Ollier WER, Peyser PA, Pramstaller PP, Ridker PM, Rivadeneira F, Ruggiero D, Saba Y, Schmidt R, Schmidt H, Slagboom PE, Smith BH, Smith JA, Sotoodehnia N, Steinhagen-Thiessen E, van Rooij FJA, Verbeek AL, Vermeulen SH, Vollenweider P, Wang Y, Werge T, Whitfield JB, Zonderman AB, Lehtimäki T, Evans MK, Pirastu M, Fuchsberger C, Bertram L, Pendleton N, Kardia SLR, Ciullo M, Becker DM, Wong A, Psaty BM, van Duijn CM, Wilson JG, Jukema JW, Kiemeney L, Uitterlinden AG, Franceschini N, North KE, Weir DR, Metspalu A, Boomsma DI, Hayward C, Chasman D, Martin NG, Sattar N, Campbell H, Esko T, Kutalik Z, Wilson JF.
Nat Commun. 2017 Oct 13;8(1):910. doi: 10.1038/s41467-017-00934-5.
PMID: 29030599
Enhanced Nociception in Angelman Syndrome Model Mice.
McCoy ES, Taylor-Blake B, Aita M, Simon JM, Philpot BD, Zylka MJ.
J Neurosci. 2017 Oct 18;37(42):10230-10239. doi: 10.1523/JNEUROSCI.1018-17.2017. Epub 2017 Sep 20.
PMID: 28931574
Precisely Where Are We Going? Charting the New Terrain of Precision Prevention.
Meagher KM, McGowan ML, Settersten RA Jr, Fishman JR, Juengst ET.
Annu Rev Genomics Hum Genet. 2017 Aug 31;18:369-387. doi: 10.1146/annurev-genom-091416-035222. Epub 2017 Apr 24. Review.
PMID: 28441061