Gene Symbol

 Alox5

Gene Name

5-lipoxygenase (5LO)

Chromosome

 6
Ensembl ID
 ENSMUSG00000025701

ES Cell Line

 E14TG2a
 
PCR Primers


Endogenous GAACTGCCCAATAATTGCCTACCC
Common CTCCCAGTCCCATCAGTTCTCAAT
Targeted GCTTCCTCGTGCTTTACGGTAT

 

 

Phenotype

 

 

 

 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Related Publications

 

Goulet JL, Griffiths RC, Ruiz P, Mannon RB, Flannery P, Platt JL, Koller BH,
Coffman TM. Deficiency of 5-lipoxygenase accelerates renal allograft rejection in mice. J Immunol. 2001 Dec 1;167(11):6631-6.

Goulet JL, Griffiths RC, Ruiz P, Spurney RF, Pisetsky DS, Koller BH, Coffman
TM. Deficiency of 5-lipoxygenase abolishes sex-related survival differences in
MRL-lpr/lpr mice. J Immunol. 1999 Jul 1;163(1):359-66.

Goulet JL, Snouwaert JN, Latour AM, Coffman TM, Koller BH. Altered inflammatory responses in leukotriene-deficient mice. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12852-6.