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Gene Symbol |
Scnn1g |
| Gene Name |
amiloride-sensitive epithelial sodium channel |
Chromosome |
7 |
Celera ID Ensembl ID |
mCG17937 ENSMUSG00000000216 |
ES Cell Line |
E14TG2a |
PCR Primers |
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Phenotype
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Targeted deletion results in neonatal lethality (death most likely caused by hyperkalemia). Characterized by a slowing of fetal lung liquid clearance and severe total body electrolyte disturbance. |
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Related
Publications |
Clarke, Lane L., Barbara R. Grubb, Sheriv E. Gabriel, Oliver Smithies, Beverly H. Koller, and Richard C. Boucher. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science 257:1125-1128, 1992. |
