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Gene Symbol |
Alox5ap |
| Gene Name |
5-lipoxygenase-activating protein (FLAP) |
Chromosome |
5 |
Ensembl ID |
ENSMUSG00000029653 |
ES Cell Line |
E14TG2a |
| PCR
Primers |
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Phenotype
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FLAP (-/-) mice are exhibit normal development and growth. |
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Related
Publications |
Griffiths RJ, Smith MA, Roach ML, Stock JL, Stam EJ, Milici AJ, Scampoli DN, Eskra JD, Byrum RS, Koller BH, McNeish JD. Collagen-induced arthritis is reduced in 5-lipoxygenase-activating protein-deficient mice. J Exp Med. 1997 Mar 17;185(6):1123-9. Byrum RS, Goulet JL, Griffiths RJ, Koller BH. Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses. J Exp Med. 1997 Mar 17;185(6):1065-75. Voelkel NF, Tuder RM, Wade K, Hoper M, Lepley RA, Goulet JL, Koller
BH, Fitzpatrick F. Inhibition of 5-lipoxygenase-activating protein
(FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension
in hypoxic rats. J Clin Invest. 1996 Jun 1;97(11):2491-8.
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