Gene Symbol

Gene Name

Chromosome

Celera ID
Ensembl ID

Jackson Labs Cftr Link

ES Cell Line

Targeting Construct

Phenotype

Koller, Beverly H., Hyung-Suk Kim, Anne M. Latour, Kristen Brigman, Richard C. Boucher, Jr., Peter Scambler, Brandon Wainwright, and Oliver Smithies. Toward an animal model of cystic fibrosis: Targeted interruption of exon 10 of cystic fibrosis transmembrane regulator gene in embryonic stem cells. Proc. Natl. Acad. Sci. USA 88:10730-10734, 1991.

Clarke, Lane L., Barbara R. Grubb, Sheriv E. Gabriel, Oliver Smithies, Beverly H. Koller, and Richard C. Boucher. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science 257:1125-1128, 1992.

Snouwaert, John N., Kristen K. Brigman, Anne M. Latour, Nadia M. Malouf, Richard C. Boucher, Oliver Smithies, and Beverly H. Koller. An animal model for cystic fibrosis made by gene targeting. Science 257:1083-1088, 1992.

Gabriel, S. E., K. N. Brigman, B. H. Koller, R. C. Boucher, and M. J. Stutts. Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model. Science 266:107-109.1994

Snouwaert, J.N., K.K. Brigman, A.M. Latour, E. Iraj, U. Schwab, M.I. Gilmour, and B.H. Koller. A murine model of cystic fibrosis. J. Respir. Crit. Care Med. 151:S59-S64, 1995.

Cressman, V.L., Hicks, E.M., Funkhouser, W.K., Backlund, D.C. and B.H. Koller. The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice. Am. J. Respir. Cell Mol. Biol., 19 853-866, 1998.