Gene Symbol

Gene Name

Chromosome

ES Cell Line

Targeting Construct

Phenotype

Nguyen M, Solle M, Audoly LP, Tilley SL, Stock JL, McNeish JD, Coffman TM, Dombrowicz D, Koller BH. Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production. J Immunol. 2002 Oct 15;169(8):4586-93.

Nataraj C, Thomas DW, Tilley SL, Nguyen MT, Mannon R, Koller BH, Coffman TM. Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. J Clin Invest. 2001 Oct;108(8):1229-35.

Audoly LP, Ruan X, Wagner VA, Goulet JL, Tilley SL, Koller BH, Coffman TM,
Arendshorst WJ. Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics. Am J Physiol Heart Circ Physiol. 2001 Jan;280(1):H327-33.

Audoly LP, Tilley SL, Goulet J, Key M, Nguyen M, Stock JL, McNeish JD,
Koller BH, Coffman TM. Identification of specific EP receptors responsible for the hemodynamic effects of PGE2. Am J Physiol. 1999 Sep;277(3 Pt 2):H924-30.

Tilley SL, Audoly LP, Hicks EH, Kim HS, Flannery PJ, Coffman TM, Koller BH. Reproductive failure and reduced blood pressure in mice lacking the EP2
prostaglandin E2 receptor. J Clin Invest. 1999 Jun;103(11):1539-45.

Goulet JL, Wang CY, Koller BH. Embryonic stem cell lines from MRL mice allow genetic modification in a murine model of autoimmune disease. J Immunol. 1997 Nov 1;159(9):4376-81.