Gene Symbol

 Pcp2

Gene Name

Purkinje cell protein-2

Chromosome
 8

Celera ID
Ensembl ID

 mCG20293
ENSMUSG00000004630

ES Cell Line

 E14TG2a
 
Probe Primers


CCTGCCTGTTTCTTGAGTAC
CTTCAGTTCCTCAAGTCCCA

Phenotype

 

No behavioral abnormalities (such as ataxia, intention tremor, or loss of balance) characteristically associated with cerebellar deficiency could be detected in PCP2 (-/-) mice. The structure and shape of Purkinje cells is not affected in the mutant animals and vision does not appear to be impaired.

 



 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Related Publications

 

Mohn AR, Feddersen RM, Nguyen MS, Koller BH. Phenotypic analysis of mice lacking the highly abundant Purkinje cell- and bipolar neuron-specific PCP2 protein. Mol Cell Neurosci. 1997 Jan;9(1):63-76.