Koller, B.H., B. Dunlap, J. Hank, S.L. Wee, and F.H. Bach. Family of large surface proteins on human lymphocytes. Scand. J. Immunol. 12:525, 1980

Dunlap, B., P.F. Mixter, B. Koller, A. Watson, M.B. Widmer, and F.H. Bach. Molecular relationships between large membrane proteins (LMP) expressed on T and B lymphocytes. J. Immunol. 125:1829, 1980

Dunlap, B., B. Koller, J. Hank, M.B. Widmer, and F.H. Bach. Differences in cell surface phenotype of functionally disparate cloned T cells. Trans. Proc. XIII:1143, 1981

Bach, F.H., B.J. Alter, B. Dunlap, B. Koller, C. Orosz, N. Roehm, and M.B. Widmer. Allo-responsive T lymphocytes and their differentiation markers. Fed. Proc. 40:1466, 1981

LeBien, T., J.G. Bradley, and B. Koller. Preliminary structural characterization of the leukocyte cell surface molecule recognized by monoclonal antibody TA 1. J. Immunol. 130:1833-1836, 1983

Koller, B.H., and H.T. Orr. Cloning and complete sequence of an HLA-A2 gene: Analysis of two HLA-A alleles at the nucleotide level. J. Immunol. 134:2727-2733, 1985

Koller, B.H., F.E. Ward, R. DeMars, and H.T. Orr. Comparison of multiple HLA-A alleles at the DNA level by using Southern blotting and HLA-A specific probes. J. Immunol. 135:4229-4234, 1985

Shimizu, Y., B. Koller, D. Geraghty, H. Orr, Yoji Shimizu, and Robert DeMars. Transfer of cloned human class I MHC genes into HLA-mutant human lymphoblastoid cells. Mol. Cell Biol. 6:1074-1087, 1986

Carroll, M. C., P. Katzman, E. M. Alicot, B. H. Koller, D. E. Geraghty, H. T. Orr, J. L. Strominger, and T. Spies. Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes. Proc. Natl. Acad. Sci. USA 84:8535-8539, 1987

Geraghty, Daniel E., Beverly H. Koller, and Harry T. Orr. A human major histocompatibility complex I gene that encodes a protein with a shortened cytoplasmic segment. Proc. Natl. Acad. Sci. USA 84:9145-9149, 1987

Shimizu, Yoji, Daniel E. Geraghty, Beverly H. Koller, Harry T. Orr, and Robert Demars. Transfer and expression of three cloned human non-HLA-A,B,C class I major histocompatibility complex genes in mutant lymphoblastoid cells. Proc. Natl. Acad. Sci. USA 85:227-231, 1988

Koller, Beverly H., Daniel E. Geraghty, Yoji Shimizu, Robert DeMars and Harry T. Orr. HLA-E: A novel HLA class I gene expressed in resting T lymphocytes. J. Immunol. 141:897-904, 1988

Mizano, S., J. A. Trapani, B. H. Koller, B. Dupont, S. Y. Yang. Isolation and nucleotide sequence of a cDNA clone encoding a novel HLA class I gene. J. Immunol. 140:4024-4030, 1988

Koller, Beverly H., Daniel E. Geraghty, Robert DeMars, Lisa Duvick, Stephen S. Rich, and Harry T. Orr. Chromosomal organization of the human major histocompatibility complex class I gene family. J. Exp. Med. 169:469-480, 1989

Uckun, Faith M., Atsushi Muraguchi, Jeffrey A. Ledbetter, Tadamitsu Kishimoto, Richard T. O'Brien, James S. Roloff, Kazimiera Gajl-Peczalska, Arthur Provisor, and Beverly Koller. Biphenotypic leukemic lymphocyte precursors in CD2+Cd19+ acute lymphoblastic leukemia and their putative normal counterparts in human fetal hematopoietic tissues. Blood 73:1000-1015, 1989

Koller, Beverly H., Lora J. Hagemann, Thomas Doetschman, John R. Hagaman, Shiu Huang, Phillip J. Williams, Neal L. First, Nobuyo Maeda, and Oliver Smithies. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. Proc. Natl. Acad. Sci. USA 86:8927-8931, 1989

Koller, Beverly H. and Oliver Smithies. Inactivating the b 2-microglobulin locus in mouse embryonic stem cells by homologous recombination. Proc. Natl Acad. Sci. USA 86:8932-8935, 1989

Geraghty, Daniel E., X. H. Wei, Harry T. Orr, and Beverly H. Koller. Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetative element. J. Exp. Med. 171:1-18, 1990

Reid, L., R. Gregg, O. Smithies, and B. H. Koller. Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells. Proc Natl. Acad. Sci. USA 87:4299-4303, 1990

Koller, Beverly H., Philippa Marrack, John W. Kappler, and Oliver Smithies. Normal development of mice deficient in b2M, MHC Class I proteins, and CD8+ T Cells. Science 248:1227-1230, 1990

Höglund, Petter, Claes Öhlen, Ennio Carbone, Lars Franksson, Hans-Gustaf Ljunggren, Ann Latour, Beverly Koller, and Klas Kärre. Recognition of b2-microglobulin-negative (b2m-/-) T-cell blasts by natural killer cells from normal but not from b2m- mice: Nonresponsiveness controlled by b2m-/- bone marrow in chimeric mice. Proc. Natl. Acad. Sci. USA 88:10332-10336, 1991

Koller, Beverly H., Hyung-Suk Kim, Anne M. Latour, Kristen Brigman, Richard C. Boucher, Jr., Peter Scambler, Brandon Wainwright, and Oliver Smithies. Toward an animal model of cystic fibrosis: Targeted interruption of exon 10 of cystic fibrosis transmembrane regulator gene in embryonic stem cells. Proc. Natl. Acad. Sci. USA 88:10730-10734, 1991

Markmann J. F., H. Bassiri, N. M. Desai, J. S. Odorico, J. I. Kim, B. H. Koller, O. Smithies, and C. F. Barker. Indefinite survival of MHC class I-deficient murine pancreatic islet allografts. Transplantation 54: 1085-1089, 1992

Flynn J. L., M. M. Goldstein, K. J. Triebold, B. Koller, and B. R. Bloom. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA 89: 12013-12017, 1992

Glas R., L. Franksson, C. Ohlen, P. Hoglund, B. Koller, H. G. Ljunggren, and K. Karre. Major histocompatibility complex class I-specific and -restricted killing of b 2-microglobulin-deficient cells by CD8+ cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. USA 89: 11381-11385, 1992

Geraghty D. E., B. H. Koller, J. Pei, and J. A. Hansen-J-A. Examination of four HLA class I pseudogenes. Common events in the evolution of HLA genes and pseudogenes. J. Immunol. 149:1947-1956, 1992

Geraghty D. E., B. H. Koller, J. A. Hansen, and H. T. Orr. The HLA class I gene family includes at least six genes and twelve pseudogenes and gene fragments. J. Immunol. 149:1934-1946, 1992

Rajan T. V., F. K. Nelson, L. D. Shultz, B. H. Koller, and D. L. Greiner. CD8+ T lymphocytes are not required for murine resistance to human filarial parasites. J. Parasitol. 78:744-746, 1992

Spriggs, M. K., B. H. Koller, T. Sato, P. J. Morrissey, W. C. Fanslow, O. Smithies, R. F. Voice, M. B. Widmer, and C. R. Maliszewski. Beta 2-microglobulin-, CD8+ T-cell-deficient mice survive inoculation with high doses of vaccinia virus and exhibit altered IgG responses. Proc. Natl. Acad. Sci. U S A 89:6070-6074, 1992

Clarke, Lane L., Barbara R. Grubb, Sheriv E. Gabriel, Oliver Smithies, Beverly H. Koller, and Richard C. Boucher. Defective epithelial chloride transport in a gene-targeted mouse model of cystic fibrosis. Science 257:1125-1128, 1992

Snouwaert, John N., Kristen K. Brigman, Anne M. Latour, Nadia M. Malouf, Richard C. Boucher, Oliver Smithies, and Beverly H. Koller. An animal model for cystic fibrosis made by gene targeting. Science 257:1083-1088, 1992

Muller, Daniel, Beverly H. Koller, J. Lindsay Whitton, Katherine E. LaPan, Kristen K. Brigman, and Jeffrey A. Frelinger. LCMV-specific, Class II-restricted cytotoxic T cells in b2-microglobulin-deficient mice. Science 255:1576-1578, 1992

Koller, B.H., and O. Smithies. Homologous recombination: A new tool for studying immunological questions. Annual Review of Immunology 10:705-730, 1992

Muller, D., B.H. Koller, K. LaPan, K.K. Brigman, and J.A. Frelinger. MHC class I deficient mice kill virus infected cells using CD4+ MHC class II. Science 255:1576-1578, 1992

Tartleton, R.L., B.H. Koller, A. Latour, and M. Postan. Susceptibility of b2-microglobulin-deficient to Trypanosoma cruzi infection. Nature 356:338-340, 1992

Dombrowicz, D., V. Flamand, K. Brigman, B.H. Koller and J.P. Kinet. Abolition of anaphlaxis by targeted disruption of the high affinity immunoglobulin E receptor * chain gene. Cell 75: 969-976, 1993

Desai, N. M., H. Bassiri, J. S. Odorico, B. H. Koller, O. Smithies, A. Naji, C. F. Barker, and J. F. Markmann. Pancreatic islet allograft and xenograft survival in CD8+ T-lymphocyte-deficient recipients. Transplant Proc. 25:961-962, 1993

Desai, N. M., H. Bassiri, J. Kim, B. H. Koller, O. Smithies, C. F. Barker, A. Naji, and J. F. Markmann. Islet allograft, islet xenograft, and skin allograft survival in CD8+ T lymphocyte-deficient mice. Transplantation 55:718-722, 1993

Coffman, T., S. Geier, S. Ibrahim, R. Griffiths, R. Spurney, O. Smithies, B. Koller, and F. Sanfilippo. Improved renal function in mouse kidney allografts lacking MHC class I antigens. J. Immunol. 151:425-435, 1993

Gabriel, S.E., K. Brigman, B.H. Koller, R.C. Boucher, and M.J. Stutts. Cystic fibrosis heterozygote resistance to cholera toxin in the cystic fibrosis mouse model. Science 266: 107-110, 1994

Goulet, J., J.N. Snouwaert, A.M. Latour, T.M. Coffman, and BH. Koller. Altered inflammatory responses in leukotriene-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 91: 12852-12856, 1994

Roach, M.L., J.L. Stock, R. Byrum, B.H. Koller, and J.D. McNeish. A new embryonic stem cell line from DBA/11ac mice allows genetic modification in a murine model of human inflammation. Experimental Cell Res. 221:153-156, 1995

Engel, P., L.J. Zhou, D.C. Ord, S. Sato, B. Koller, and T.F. Tedder. Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signaltransduction molecule. Immunity 3:39-50, 1995

Ohlen, C., P. Hoglund, C.L. Sentman, E. Carbone, H.G. Ljunggren, B. Koller, and K. Karre. Inhibition of natural killer cell-mediated bone marrow graft rejection by allogeneic major histocompatibility complex class I, but not class II molecules. Eur. J. Immunol. 25:1286-91, 1995

Snouwaert, J.N., K.K. Brigman, A.M. Latour, E. Iraj, U. Schwab, M.I. Gilmour, and B.H. Koller. A murine model of cystic fibrosis. J. Respir. Crit. Care Med. 151:S59-S64, 1995

Gowen, L.C., B.L. Johnson, A.M. Latour, K.K. Sulik, and B.H. Koller. Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities. Nature Genet. 12:191-194, 1996

Dombrowicz, D., A.T. Brini, V. Flamand, E. Hicks, J.N. Snouwaert, J-P. Kinet and B.H. Koller. Anaphylaxis Mediated through a Humanized High Affinity IgE Receptor. J. Immunol. 157:1645-1651, 1996

Voelkel, N.F., R.M. Tuder, K. Wade, M. Hoper, R.A. Lepley, J.L. Goulet, B.H. Koller, and F. Fitzpatrick. Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats. J. Clin. Invest. 97:2491-2498, 1996

Stanford, W.L., S. Haque, R. Alexander, X. Liu, A.M. Latour, H.R. Snodgrass, B.H. Koller and P. Flood. Altered proliferative response by T lymphocytes of Ly-6S (Sca-1) null mice. J Exp. Med. 186: 705-17

Griffiths,R. J., M.A. Smith, M.L.Roach, J.L. Stock, E.J. Stam, A.J. Milici, D.N.Scampoli, J.D. Eskra, R.S. Byrum, B.H. Koller and J.D. McNeish. Collagen-induced arthritis is reduced in 5-lipoxygenase-activating protein-deficient mice. J. Exp. Med. 185:1123-9

Byrum, R.S., J.L. Goulet, R.J. Griffiths, and B.H. Koller. Role of the 5-lipoxygenase activating protein (FLAP) in murine acute inflammatory responses. J. Exp. Med. 185: 1065, 1997

Mohn, A.R., R.M. Feddersen, M.S. Nguyen, and B.H. Koller. Phenotypic analysis of mice lacking the highly abundant purkinje cell- and bipolar neuron-specific PCP2 protein. Mol. Cell. Neurosci. 9:63-76, 1997

Goulet, J.L., C-Y Wang, and B.H. Koller. Embryonic stem cell lines from MRL mice allow genetic modification in a murine model of autoimmune disease. J. Immunol. 159:4376-4381, 1997

Nguyen, M., T. Camenisch, J.N. Snouwaert, E. Hicks, T.M. Coffman, P.A.W. Anderson, N.N. Malouf, and B.H. Koller. The prostaglandin receptor EP4 triggers remodeling of the cardiovascular system at birth. Nature 390:78-81, 1997

Dombrowicz,D., Lin S., Flamand, V., Brini, A.T. Koller, B.H., and J-P Kinet. Allergy-associated FcR? is a molecular amplifer of IgE- and IgG-mediated in vivo responses. Immunity 8:517-529, 1998

Gowen, L.C., Avrutskaya, A.V., Latour, A.M., Koller, B.H and S.A. Leadon. Brca1 is required for the Transcription-Coupled Repair of Oxidative DNA Damage. Science 281:1009-1012, 1998

Barker, P.M., Nguyen, M.S., Gatzy, J.T., Grubb, B., Norman, Hilary, Hummler, E., Rossier, B., Boucher, R.C. and B.H. Koller. Role of gENaC Subunit in Liquid Clearance and Electrolyte Balance in Newborn Mice. JCI 102:1634-1640, 1998

Flemming, E.R., Athirakul K, Oliverio, M.I., Key, M, Goulet J., Koller, B.H. and T.M. Coffman. Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2. Am J Physiol, 275: F955-F961, 1998

Thomas, D.W., Mannon, R.B., Mannon, P.J., Latour A., Oliver, J.A., Hoffman, M., Smithies O., Koller, B.H., and T.M. Coffman. Coagulation defects and altered hemodynamic responses in mice lacking receptors for thromboxane A2. J Clin Invest, 102,1994-2001, 1998

Cressman, V.L., Hicks, E.M., Funkhouser, W.K., Backlund, D.C. and B.H. Koller. The relationship of chronic mucin secretion to airway disease in normal and CFTR-deficient mice. Am. J. Respir. Cell Mol. Biol., 19 853-866, 1998

Cressman, V.L., Backlund, D.C., Hicks, E.M., Gowen, L.C., Godfrey, D.V.M., and B.H. Koller. Mammary tumor formation in p53- and BRCA1-deficient mice. Cell Growth and Differentation, 10: 1-10, 1999

Camenisch, T.D., Koller, B.H., Earp, H.S., and G. K. Matsushima. A novel receptor tyrosine kinase, mer inhibits TNR-a production and lipopolysaccharide-induced endotoxic shock. J. Immunol. 162: 3498-3503, 1999

Tilley, S.L., Audoly, L.P., Hicks, E.H., Kim, H-S, Flannery, P.J., Coffman, T.M., and B.H. Koller. Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor. J. Clin. Invest. 103: 1539-1545, 1999

Cressman, V.L., Lazarowski, Eduardo, Homolya, L., Boucher, R.C., Koller, B.H., Grubb, B.R. Effect of P2Y2 receptor gene targeting on nucleotide regulation of murine epithelial Cl- transport. JBC 274: 26461-26468, 1999

Homolya, L., Watt, W.C., Lazarowski, E.R., Koller, B.H., R. Boucher. Nucleotide-regulated calcium signaling in lung fibroblasts and epithelia cells from normal and P2Y2 receptor (-/-) mice. JBC 274: 26454-26460,1999

Audoly, L.P., Tilley, S.L., Goulet, J., Key, M., M., Nguyen, Stock, J., McNeish, J., Koller, B.H., and T.M. Coffman. Identification of specific EP receptors responsible for the hemodynamic effects of PGE2 Am. J. Physiol. 277: H924-H930, 1999

Cressman, V.L., Backlund, D.C., Avrutskaya, A.V., Leadon, S.A., Godfrey, V. and B.H. Koller. Growth retardation, DNA repair defects and lack of spermatogenesis in BRCA1 deficient mice. Mol Cell Bio. 19:7061-7075, 1999

Mohn, A. R, Gainetdinov, R., Caron, M.G. and B.H. Koller. Mice with Reduced NMDA Receptor Expression Display Behaviors Related to Schizophrenia. Cell 98:427-436, 1999

Itoh-Lindstrom, Y., Piskurich, J.F., Felix, N. J., Wang, Y., Brickey, W. J., Platt, J. L., Koller, B. H., and J. P.-Y. Ting. Reduced IL-4, Lipopolysaccharide, and IFN-?-Induced MHC Class II Expression in Mice Lacking Class II Transactivator Due to Targeted Deletion of the GTP-Binding Domain. J of Immunol.163: 2425-2431, 1999

Fabre, J-E, Nguyen, T., Latour, A., Goodman, J., Audoly, L., Coffman, T., and B.H. Koller. Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. Nature Medicine 5:1199-1202.1999.

Snouwaert, J. N., Gowen, L. C., Latour, A. M., Mohn, A. R., Xiao, A., DiBiase, L., and B.H. Koller. BRCA1 deficient embryonic stem cells display a decreased homologus recombination frequency and an increased frequency of non-homlogous recombination that is corrected by expression of a Brca1 transgene. Oncogene, 18 7900-7907 1999

Moynahan, M.E., Chiu, J.W., Koller, B.H., and Jasin, M. BRCA1 controls homology-directed DNA repair. Mol.Cell. 4:511-518, 1999

Byrum, R.S., Goulet, J.L., Snouwaert, J.N., Griffiths, R.J. and B.H. Koller. Determination of the Contribution of Peptidyl Leukotrienes and Leukotriene B4 in Acute Inflammatory Responses using 5-lypoxygenase- and LTA4 hydrolase-deficient Mice. J of Immunol. 163:6810-6819, 1999

Salvatore, C.A., Tilley, S.L., Latour, A.M., Fletcher, S., Koller, B.H. and M.A. Jacobson. Disruption of the A3 Adenosine Receptor Gene in Mice and its Effect on Stimulated Inflammatory Cells. JBC. 275:4429-4434, 2000

Tilley, S.L. Wagoner, V.A., Salvatore, C.A., Jacobson, M.A., and B.H. Koller. Adenosine and inosine mediated increases in cutaneous vasopermeability occur through A3 receptor activation of mast cells. J Clin. Invest. 105:361-367 2000

Pace, A.J., Lee, E., Athirakul, K., Coffman, T.M., O’Brien, D., A., and B.H. Koller. Failure of spermatogenesis in mouse lines deficient in the Na+-K+-2Cl- cotransporter. J. Clin. Invest. 105:441-450, 2000

Goulet, J.L., Byrum, R.S., Key, M.L., Nguyen, M-T., Wagoner, V.A., and B.H. Koller. Genetic factors determine the contribution of leukotreines to acute inflammatory responses. J of Immunol. 164:4899-4907, 2000

Bhattacharyya A. Ear US. Koller BH. Weichselbaum RR. Bishop DK. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51and survival following treatment with the DNA cross-linking agent cisplatin. JBC. 275(31):23899-903, 2000

Bennett LM. McAllister KA. Malphurs J. Ward T. Collins NK. Seely JC. Gowen LC. Koller BH. Davis BJ. Wiseman RW. Mice heterozygous for a Brca1 or Brca2 mutation display distinct mammary gland and ovarian phenotypes in response to diethylstilbestrol. Cancer Research. 60(13):3461-9, 2000

Loftin, C.D. Trivedi, D.B., Tiano, H.F., Clark, J.A., Lee, C.A., Epstein, J.A., Morham, S.G., Breyer, M.D., Nguyen M-T, Hawkins, B.M., Goulet, J.L., Smithies, O., Koller, B.H., and R. Langenbach. Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2. PNAS 98: 1059-1064, 2001

Staudinger, J.L., Goodwin, B., Jones, S.A.., Hawkins-Brown, D., MacKenzie, K.I., Latour, A., Liu, Y., Klaassen, C.D., Brown, K.K., Reinhard, J., Willson, T.M., Koller, B.H. and S.A.. Kliewer. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. PNAS: 98(6):3369-3374, 2001

Aprelikova, O, Pace, A. J. , Fang,B, Koller, B.H and E.T. Liu. BRCA1 is a co-regulator of 14-3-3 sigma gene expression, submitted, JBC in press

Backlund, M.G, Trasti, S.L, Backlund, D.C., Cressman,V.L, Godfrey, V., B.H. Koller. Impact of Ionizing Radiation and Genetic Background on Mammary Tumorigenesis in p53-Deficient Mice. Cancer Research in press

Fabre, J-E, Nguyen, M-T., Athirakul, K., Coggins, K., McNeish, J.D., Austin, S., FitzGerald, G.A., Parise, L.K., Coffman, T.M., and B.H. Koller. The prostaglandin EP3 receptor regulates Platelet Aggregation and Thrombosis. JCI 107(5)603-610 2001

Tilley, S.L., Coffman, T.M., and B.H. Koller. Mixed Messages: Modulation of Inflammation and Immune Responses by Prostaglandins and Thromboxanes. JCI 108 (1) 15-23