Janet Rubin, MD

Janet Rubin, MD

Office: 919-966-0134
Appts: 984-974-2950
Curriculum Vitae 

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Professor of Medicine, Division of Endocrinology and Metabolism
Joint Professor, Pediatrics and Pharmacology
Adjunct Professor, Bioengineering
Vice Chair for Research, Department of Medicine 

Specialty Areas: Osteoporosis, metabolic bone disease, molecular research.

Chronology: MD: Brown University, 1980; Intern and Resident: Northwestern University Medical Center, 1980-1983; Endocrinology and Metabolism Fellowship: University of California, San Diego, 1980-1983; Instructor Medicine: UCSD, 1983-1986; Faculty and Professor of Medicine with tenure: Emory University, 1986-2006; Physican: VAMC Atlanta, 1986-2006; Professor of Medicine with tenure: University of North Carolina, 2006-present.

Dr. Rubin practices Endocrinology in the Meadowmont Endo/Diabetes Center with a specialty in Osteoporosis and metabolic bone disease, and is responsible for bone density testing there. At the University Dr Rubin continues her decades long research into bone remodeling. The laboratory is currently investigating how bone marrow stem cells are directed to become osteoblasts or adipocytes, with a particular interest in how exercise regulates this divergent differentiation through the cellular cytoskeleton. Her research is funded by the NIH.

Dr. Rubin is also active in DOM leadership as the Vice-Chair for Research. Her interests are in junior faculty research development, and promotion of research throughout the Department.

Selected Bibliography:

Pagnotti GM, Chan ME, Adler BJ, Shroyer KR, Rubin J, Rubin CT. "Low intensity mechanical signals slow tumor progression and osteolysis in a mouse model of multiple myeloma." Bone, in press 2016.

Sen B, Xie Z, Thomas J, Uzer G, Styner M, Rubin J. "Intranuclear actin regulates osteogenesis." Stem Cells, 33(10):3065-76, 2015.

Uzer G, Thompson WR, Case N, Xie Z, Sen B, Yen S, Styner M, Rubin C, Judex S, Burridge K, Rubin J. "Cell mechanosensitivity to extremely low magnitude signals is enabled by a LINCed nucleus." Stem Cells, 33(6):2063-2076, 2015.