Julie Sharpless, MD

Julie Sharpless, MD

Office: 919-966-0134
Appts: 984-974-2950
Curriculum Vitae 

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Associate Professor of Medicine
Joint Appointment in Neurosurgery

Director, UNC Multidisciplinary Pituitary Clinic 

Specialty Areas: Pituitary hormone disorders including acromegaly, Cushing’s disease, prolactinomas, hypopituitarism and general endocrinology.

Chronology: MD: Yale School of Medicine, 1992; Internship and Residency: Massachusetts General Hospital, 1992-1995; Endocrinology Fellowship: Massachusetts General Hospital Reproductive Endocrine Unit, 1995-1998; Joslin Diabetes Center Women’s Health Clinic, 1998-2002; Beth Israel Bone Clinic, 1996-1998; University of North Carolina School of Medicine, 2002-present; Director, UNC Multidisciplinary Pituitary Clinic, 2003-present. 

Dr. Sharpless’s practice focuses on pituitary endocrinology, including medical treatment for pituitary deficiencies, acromegaly, Cushing’s disease and prolactinomas. She also runs UNC’s Multidisciplinary Pituitary Clinic with the Neurosurgery team to prepare patients for pituitary surgery and perform pre- and post-operative diagnostic testing. This clinic coordinates care and facilitates lab testing, imaging and specialty visits for patients with many types of pituitary tumors. Dr. Sharpless also teaches medical students, residents, fellows and doctors from other specialties about pituitary disease and conducts research in pituitary medicine.

Selected Publications

Comparative Safety of Testosterone Dosage FormsLayton JB, Meier CR, Sharpless JL, Stürmer T, Jick SS, Brookhart MA. JAMA Intern Med. 2015 Jul;175(7):1187-96. doi: 10.1001/jamainternmed.2015.1573. Erratum in: JAMA Intern Med. 2015 Jul;175(7):1248. PMID:25962056

Comparison of multiple methods for identification of hyperprolactinemia in the presence of macroprolactinMcCudden CR, Sharpless JL, Grenache DG. Clin Chim Acta. 2010 Feb;411(3-4):155-60. doi: 10.1016/j.cca.2009.10.020. Epub 2009 Nov 4. PMID:19895797

Predictors and incidence of central diabetes insipidus after endoscopic pituitary surgerySigounas DG, Sharpless JL, Cheng DM, Johnson TG, Senior BA, Ewend MG. Neurosurgery. 2008 Jan;62(1):71-8; discussion 78-9. doi: 10.1227/01.NEU.0000311063.10745.D8. PMID:18300893