Associate Professor of Medicine, Cell Biology,
My research focuses on elucidating genetic mechanisms underlying stemness and developing translational models to establish a finer understanding of stem cell-driven regeneration dynamics in homeostasis and injury. Using a combination of genetic mouse models and micro-frabricated bioengineered platforms, we are exploiting the self-renewal capacity and multipotency of ISCs to develop long-term ex vivo models of the intestine and colon with primary tissues. These biomimetic models offer new solutions for compound screening and cell-based therapies.
Education and Training
|BS||University of California, San Diego||Biochemistry and Chemistry|
|PhD||University of North Carolina||Genetics and Molecular Biology|
|Post-Doctoral Research||UNC GI Division||Molecular Pathogenesis of Liver Fibrosis|
|Post-Doctoral Research||UNC Department of Genetics||Neural Stem Cells|