Dr. Mohanish Deshmukh's laboratory has collaborated with the Human Pluripotent Stem Cell Core Facility on a project focused on understanding the molecular mechanism of the rapid cell death of hES cells after DNA damage. This research shows that undifferentiated hES cells maintain the pro-apoptotic protein Bax in its active state at the Golgi and not at the mitochondria, thus priming the cells for a rapid cell death upon DNA damage. The paper has been published in Molecular Cell and was highlighted by the News Room-UNC Health Care as well as by The Scientist and Yahoo!News.

A link to the paper can be found here: http://www.ncbi.nlm.nih.gov/pubmed/22560721

Links to:

News Room-UNC Health Care

http://news.unchealthcare.org/news/2012/may/stem-cells-poised-to-self-destruct-for-the-good-of-the-embryo?utm_source=vitalsigns&utm_medium=email&utm_campaign=may10vs

http://www.sciencedaily.com/releases/2012/05/120503125645.htm

The Scientist:

http://the-scientist.com/2012/05/03/stem-cell-suicide-switch/

Yahoo!News

http://news.yahoo.com/stem-cells-carry-suicide-pills-instant-death-160652902.html

The 4th Southeast Stem Cell Consortium is dedicated to bring together scientists from neighboring institutions to promote the pluripotent stem cell research and acts as a technical resource for investigators in the field.

Where: Florida State University 
Turnbull Conference Center 
Tallahassee

When: 28-29 September,2012

http://www.sestemcells.uga.edu/index.html