Dr. Mohanish Deshmukh's laboratory has collaborated with the Human Pluripotent Stem Cell Core Facility on a project focused on understanding the molecular mechanism of the rapid cell death of hES cells after DNA damage. This research shows that undifferentiated hES cells maintain the pro-apoptotic protein Bax in its active state at the Golgi and not at the mitochondria, thus priming the cells for a rapid cell death upon DNA damage. The paper has been published in Molecular Cell and was highlighted by the News Room-UNC Health Care as well as by The Scientist and Yahoo!News.

A link to the paper can be found here:

Links to:

News Room-UNC Health Care

The Scientist:



The 4th Southeast Stem Cell Consortium is dedicated to bring together scientists from neighboring institutions to promote the pluripotent stem cell research and acts as a technical resource for investigators in the field.

Where: Florida State University 
Turnbull Conference Center 

When: 28-29 September,2012