Need Men and Women over the age of 18 suffering from anal or rectal pain
Principal Investigator: Spencer Dorn, MD
UNC Center for Functional GI & Motility Disorders
Bioinformatics Building, CB# 7080
Chapel Hill, NC 27599-7080
Anal Fissures cause rectal pain and bleeding. Often due to constipation, anal fissures are tears in the lining of the anal canal. Affecting nearly up to 10% of the population, it is an extremely painful and debilitating condition.
If you are suffering with anal or rectal pain particularly during or after a bowel movement, you may have an anal fissure and qualify for a research study of an investigational cream (diltiazem).
If you are interested, please contact Renuka Kelapure by phone (919.843-7892) or email (email@example.com)
• Documenting anal fissure pain daily
• Documenting bowel movements and symptoms
• Giving blood samples
• Completing a no-cost physical exam
• Completing 5 visits during the 5-week study
• Self-administering study medication three times a day
Qualified participants will receive up to $425 compensation for participation.