Need Men and Women over the age of 18 with an anal fissure

Principal Investigator: Spencer Dorn, MD
UNC Center for Functional GI & Motility Disorders
Bioinformatics Building, CB# 7080
Chapel Hill, NC 27599-7080

Has your physician diagnosed you with an anal fissure?

The UNC Center for Functional GI and Motility Disorders is conducting a research study to evaluate an investigational drug (diltiazem).

If you may be interested please contact Meley Woldeghebriel by e-mail (meley_woldeghebriel@med.unc.edu) or phone (919-966-8328).

Eligibility: To be eligible, you must be over the age of 18 and less than or equal to 75 years old, and diagnosed with an anal fissure. You must be able to complete a daily phone diary for the entire study about overall anal fissure related pain.

Participation includes:
• Documenting anal fissure pain daily

• Documenting bowel movements and symptoms

• Giving blood samples

• Completing a no-cost physical exam

• Completing 5 visits during the 5-week study

• Self-administering study medication three times a day

Compensation
Qualified participants will receive up to $425 compensation for participation.