Lung Protective Ventilation


To reduce hospital mortality and length of stay for patients with acute respiratory distress syndrome (ARDS) by improving lung protective ventilation (LPV) in UNC's medical, surgical and neuroscience ICUs.


 2015 IHQI Seed Grant Program Symposium Presentation


Patients requiring mechanical ventilation have the highest risk for mortality and are the most resource intensive patient population in the hospital. Care of the mechanically-ventilated patient is complex, and requires coordination of care among physicians, nurses, respiratory therapists, pharmacists, and dieticians.

One particular challenge is adhering to lung protective ventilation (LPV), defined as tidal volumes <6 ml/kg ideal body weight (IBW). Implementation of LPV is the only intervention proven to reduce mortality in patients with the acute respiratory distress syndrome (ARDS).

A policy of LPV for all patients is challenging to implement because it requires a series of patient assessments and ventilator adjustments that are time consuming and may temporarily increase discomfort for the patient.


Thomas Bice, MD


July 2014 - June 2015