Faculty

ID Faculty Directory

The infectious diseases division has a large and growing faculty of nearly 50 physicians and researchers, working on everything from influenza to HIV/AIDS to tropical diseases and new, emerging infections.

Find Infectious Disease Physicians at UNC

HIV Clinical Research

Home to an Global HIV Prevention and Treatment Clinical Trials Unit and Center for AIDS Research, UNC is a leader in research on treatments for HIV and HIV-associated conditions. Our clinical research faculty focuses primarily on human subjects research designed to improve the clinical management of HIV in the U.S. and around the world.

Joseph Eron, MD

Michelle Floris-Moore, MD

Satish Gopal, MD

Mina Hosseinipour, MD

David Margolis, MD

David Wohl, MD

HIV/STI Epidemiology and Prevention

Long before HIV first appeared, investigators at UNC were interested in the epidemiology, treatment, and prevention of sexually transmitted infections. By improving our understanding of how HIV and other STIs spread, our faculty are continuing UNC’s long-standing commitment to the development of innovative and improved strategies for the prevention of these infections.

Adaora Adimora, MD 

Myron S. Cohen, MD

Ann Dennis, MD

Claire Farel, MD

Lisa Hightow-Weidman, MD, MPH 

Irving Hoffman, PA, MPH

Christopher Hurt, MD

Peter Leone, MD, MPH

Francis Martinson, MBChB, MPH, PhD

William Miller, MD, PhD§

Sonia Napravnik, PhD

Evelyn Byrd Quinlivan, MD

Arlene Seña-Soberano, MD, MPH 

Heidi Swygard, MD, MPH 

Joseph Tucker, MD, PhD

Becky White, MD, MPH 

HIV/STI Basic and Translational Science

Our basic and translational science faculty provides deeper insights into the mechanisms of STIs and HIV, bridging the gap between the bench and the bedside. UNC researchers have made important contributions to our understanding of how these important pathogens interact with their human hosts – and have brought us closer than ever before to a cure for HIV.

Nancie Archin, PhD

Joseph Duncan, MD, PhD

John L. Foster, PhD

J.Victor Garcia-Martinez, PhD

Cynthia Gay, MD, MPH

Nilu Goonetlleke, PhD

Marcia Hobbs, PhD

Frederick Sparling, MD

 

Emerging Infections and Tropical Medicine

UNC’s commitment to infectious diseases research goes beyond HIV and STIs. Our investigators have made key discoveries in parasitology, virology, and bacteriology – advancing our understanding of a wide variety of important pathogens, from Plasmodium to Pneumocystis, hepatitis C to tuberculosis.

Jonathan Juliano, MD

Jessica Lin, MD

Stanley M. Lemon, MD

 

Infections in Compromised Hosts

With advances in care for solid organ and stem cell transplant recipients and patients with burns over the past several decades have come important, new challenges in infectious diseases. UNC is addressing these challenges with a dedicated team of physician-scientists who are improving care for these patients and studying innovative approaches to the treatment and prevention of transplant and burn associated infections.

Pearlie Chong, MD

David van Duin, MD, PhD

Anne Lachiewicz, MD, MPH

Hospital Epidemiology

Understanding how infections develop in hospital settings is critical to developing more effective strategies to prevent their spread. For decades, UNC investigators have worked to advance the field of infection control through basic science, clinical, and epidemiological research.

William A. Rutala, PhD

Emily Sickbert-Bennett, PhD, MPH

David Weber, MD, MPH

Adjunct Faculty

Gretchen Arnoczy, MD

Irene Doherty, PhD

Peter Kazembe, MD

Affiliated Faculty

James Horton, MD

Cornelius (Kees) van Dam, MD

Adaora Adimora, MD

Professor of Medicine, School of Medicine
Professor of Epidemiology, Gillings School of Global Public Health

Adimora

Phone: (919) 966-2536
Fax: (919) 966-6714
Email: adimora@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., Yale University School of Medicine, 1981
M.P.H., University of North Carolina School of Public Health, 1993

Board Certifications

American Board of Internal Medicine, Internal Medicine, 1984
American Board of Internal Medicine, Infectious Diseases, 1986

Research Summary

Epidemiology of STDs and HIV in women and minorities

Publications

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Adimora Biosketch

Myron Cohen, MD

Associate Vice Chancellor for Global Health
Yeargan-Bate Distinguished Professor of Medicine, Microbiology and Immunology, and Epidemiology
Chief, Division of Infectious Diseases
Director, Institute for Global Health & Infectious Diseases

myron-cohenPhone: 919- 966-2536
Fax: 919-966-6714
Email: myron_cohen@med.unc.edu

Division of Infectious Diseases
2115 Bioinformatics
CB# 7030
Chapel Hill, North Carolina 27599-7030

Education

M.D., Rush Medical College, 1974

Board Certifications

Diplomate, American Board of Internal Medicine, 1977
Diplomate, Subspecialty of Infectious Disease, 1982

Clinical Interests

Biology and epidemiology of transmission of STD pathogens, including HIV

Research Summary

Dr. Cohen’s research work focuses on the transmission and prevention of transmission of STD pathogens including HIV. Much of his work has been conducted at the research sites he and his group have developed in Lilongwe, Malawi and Beijing, China. Dr. Cohen and his coworkers have identified the concentration of HIV in genital secretions required for transmission of HIV ( NEJM 336:1072, 1997; AIDS 15: 621, 2001), and the effects of genital tract inflammation on HIV (Lancet 349: 1868, 1997).

Publications

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Myron Cohen biosketch

Joseph Duncan, MD, PhD, FIDSA

Associate Professor of Medicine, School of Medicine

Alex Duncan


Phone: (919) 966-2536
Fax: (919) 966-6714
Email: joseph_duncan@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030


Education

M.D./Ph.D., University of Texas Southwestern Medical School, 2001

Research Summary

Molecular mechanisms in innate immune system signaling and role of innate immunity in sexually transmitted diseases

Publications

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Duncan Biosketch

Joseph Eron, MD

Professor of Medicine, School of Medicine
Director, Clinical Core, UNC Center for AIDS Research
Associate Director, General Clinical Research Unit
Adjunct Professor of Epidemiology, Gillings School of Global Public Health


Joe_EronDivision of Infectious Diseases 

Phone: (919) 966-2536
Fax: (919) 966-6714
Email: joseph_eron@med.unc.edu

CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., Harvard Medical School, 1984

Board Certifications

National Board of Medical Examiners, 1984
American Board of Internal Medicine, 1987
American Board of Internal Medicine, Infectious Diseases, 1991

Clinical Interests

HIV care, antiretroviral therapy including advanced patients, HIV resistance, primary HIV infection

Research Interests

My research interests are focused primarily on the study of HIV/AIDS. Current research interests include clinical development of combination antiretroviral therapy including novel agents, HIV resistance to antiretroviral therapy and the use of resistance testing and pharmacokinetic assessment to construct success therapy in treatment experienced patients. Additional interests include the study of primary (acute) HIV infection, HIV transmission and HIV penetration and antiretroviral penetration into tissue compartments such as genital track and central nervous system. Newer areas of investigation include development of a Clinical/Research HIV relational database in collaboration with SAS, development of a therapeutic HIV vaccine in conjunction with Robert Johnston Ph.D., and the study of antiretroviral combination therapy in the developing world both for treatment and prevention of transmission in conjunction with Myron S. Cohen, Charles van der Horst and colleagues.

Publications

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Eron Biosketch

Michelle Floris-Moore, MD

Clinical Associate Professor of Medicine, School of Medicine

Floris-Moore


Phone: (919) 966-4733
Fax: (919) 966-6714
Email: michelle_floris-moore@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., Cornell University, 1994
M.S., Albert Einstein College of Medicine, 2002

Research Summary

Metabolic and cardiovascular complications of HIV

Publications

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Floris-Moore Biosketch

Cynthia Gay, MD, MPH

Clinical Assistant
Professor of Medicine, School of Medicine

Gay


Phone: (919) 843-2726
Fax: (919) 966-8928
Email: cynthia_gay@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.P.H., University of North Carolina School of Public Health, 1998
M.D., University of North Carolina School of Medicine, 1999

Certification

American Board of Internal Medicine, 2002
American Board of Internal Medicine, Infectious Diseases 2007

Research Summary

acute HIV and access to HIV care

Publications

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Gay Biosketch

Lisa Hightow-Weidman, MD

Associate Professor, School of Medicine

Lisa Hightow-Weidman 2011


Phone: (919) 843-0033
Fax: (919) 966-6714
Email: lisa_hightow@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., University of Virginia, 1998
M.P.H., University of North Carolina, 2003

Research Summary

Dr. Hightow-Weidman’s research interests include primary and secondary HIV prevention interventions for gay/bisexual/non-identifying men using both the Internet and other technologies (e.g. mobile phones, SMStexting), adolescents, acute HIV infection, and linkage and retention in care for young men of color.

Publications

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Hightow-Weidman Biosketch

Mina Hosseinipour, MD, MPH

Research Associate Professor of Medicine, School of Medicine
Clinical Director, UNC Project-Malawi

Mina Hosseinipour faculty page


Phone: 265-1-755-056
Fax: 265-1-755-954
Email: mina_hosseinipour@med.unc.edu
UNC Project, Tidziwe Centre
Private Bag A-104
Lilongwe
Malawi  


Education

M.D., Northwestern University Medical School, 1995
M.P.H., University of North Carolina-Chapel Hill, 2004

Board Certifications

Board Certified, American Board of Internal Medicine, 1998
Board Certified, American Board of Internal Medicine, Infectious Diseases, 2006
Diploma, Gorgas Course in Clinical Tropical Medicine, Lima Peru, 1999
Certificate of Knowledge in Tropical Medicine, American Society of Tropical Medicine and Hygiene, 2000

Research Summary

My research interests are focused on the management of HIV disease in developing countries including prevention, interactions with endemic diseases, treatment of opportunistic infections including malignancies and monitoring strategies for antiretroviral therapy in this setting. The evaluation of the use of antiretroviral therapy as HIV prevention is one of the primary objectives of my research.

Publications

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Hosseinipour Bioksetch

 

Jonathan Juliano, MD

Assistant Professor of Medicine, School of Medicine


Phone: (919) 843-4384
Fax: (919) 966-6714
Email: jjuliano@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., University of North Carolina at Chapel Hill
Residency, University of Minnesota

Board Certifications

American Board of Internal Medicine, Infectious Diseases

Research Summary

Malaria drug resistance, diversity, and population evolution

Publications

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Juliano Biosketch

Peter Kazembe, MD

Adjunct Professor of Medicine, School of Medicine
Director, Baylor International Pediatric Program, Lilongwe, Malawi

Kazembe


Phone: 265-888-822-447
Email: pnkazembe@baylor-malawi.org

Kamuzu Central Hospital
Bottom Hospital Recruiting
Lilongwe, Malawi 

 

Education

M.D., University of Manchester

Board Certifications

American Board of Internal Medicine, Internal Medicine, 1984
American Board of Internal Medicine, Infectious Diseases, 1986

Research Summary

Pediatric antiretroviral therapy and treatment of malaria

Publications

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Kazembe Biosketch

Peter Leone, MD

Professor of Medicine, School of Medicine
Adjunct Associate Professor of Epidemiology, Gillings School of Global Public Health

Leone


Phone: (919) 250-4410
Fax: (919) 966-6714
Email:pal007@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

B.S./M.D., Combined Program, Kent State University & Northeastern Ohio Universities College of Medicine, 1982

Board Certifications

Board Certification in Internal Medicine, 1985
Board Certification in Infectious Diseases, 1990
Recertification in Infectious Diseases, 2000

Research Summary

Diagnosis and treatment of STDs

Publications

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Leone Biosketch

David Margolis, MD

Professor of Medicine, Microbiology and Immunology, Epidemiology, School of Medicine  
Director, Program in Translational Clinical Research, IGHID

Margolis


Phone: (919) 966-6388
Fax: (919) 966-0584
Email: dmargo@med.unc.edu

2060 Genetic Medicine Bldg., CB#7042
120 Mason Farm Rd.
University of North Carolina at Chapel Hill 
Chapel Hill, NC 27599-7042

Education

M.D., Tufts University

Board Certifications

American Board of Internal Medicine, Infectious Diseases

Research Interests

HIV molecular biology and virology, latency and persistence of HIV infection, antiretroviral therapy and clinical/translational investigation. Margolis lab web site.

Research Summary

Dr. Margolis is the leader of CARE:  The Collaboratory of AIDS Researchers for Eradication. CARE is a New Vision for HIV Research. CARE aims to do what no single laboratory or company can do: pursue a comprehensive collaborative search for approaches to eradicate HIV. CARE brings together some of the leading minds from top U.S. academic institutions in the field of HIV latency as well as the pharmaceutical industry in a joint consortium whose mission is to find a cure for HIV. By working together and leveraging research and resources across this consortium, the Collaboratory gives members access to technologies and tools to accelerate the work of finding a cure. CARE's efforts honor Martin Delaney, a pioneer in the field of HIV research and activism. This collaboration, much like his life's work, will bring cutting edge technology and the collaborative research endeavors of the leaders in the field of HIV research together to accelerate the development and dissemination of promising new HIV treatments. For more information, please visit www.delaneycare.org.

Publications

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Margolis Biosketch

Francis Martinson, MBChB, MPH, PhD

Research Associate Professor of Medicine
Director, UNC Project-Malawi

Martinson

Phone: 265-1-755-056
Fax: 265-1-755-954
Email: fmartinson@unclilongwe.org.mw

UNC Project
Tidziwe Centre
Private Bag A-104
Lilongwe
Malawi

Education

M.B.Ch.B., University of Ghana Medical School
Ph.D., University of North Carolina at Chapel Hill

Research Summary

HIV in Africa, prevention of mother to child transmission of HIV

Publications

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Martinson Biosketch

 

William Miller, MD, PhD, MPH

Bill_miller

Professor of Medicine, School of Medicine
Professor of Epidemiology, Gillings School of Global Public Health

Phone: (919) 966-9407 
Fax: (919) 966-6714
Email: bill_miller@unc.edu


Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, NC 27599-7030
 

M.D., The Johns Hopkins University School of Medicine, 1985
Ph.D., The Johns Hopkins University School of Medicine, 1989
M.P.H., School of Public Health,The University of North Carolina at Chapel Hill, 1997

Board Certifications

Diplomate, American Board of Internal Medicine, 1992
Diplomate, American Board of Internal Medicine, Infectious Diseases, 1994

Clinical Interests

Sexually transmitted diseases, infectious diseases, fever of unknown origin, endocarditis

Research Summary

My research focuses primarily on sexually transmitted diseases and HIV infection. A particular area of interest is targeted screening for STDs in areas with limited resources. My research interests also include international health, women's health and clinical epidemiology.

Publications

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Miller Biosketch

Evelyn Byrd Quinlivan, MD

Clinical Associate Professor of Medicine, School of Medicine
Director, Infectious Diseases Clinic

Evelyn B Quinlivan, MD


Phone: (919) 966-2536
Fax: (919) 966-6714
Email: ebq@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, NC 27599-7030

Education

M.D., Duke University, 1985

Board Certifications

Internal Medicine, Board certified, 1988
Infectious Diseases, Board certified, 2004

Clinical Interests

HIV care

Research Interests

Delivery of services and access to care for HIV-infected patients.

Publications

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Quinlivan Biosketch

William Rutala, MS, MPH, PhD

Director, Statewide Program for Infection Control and Epidemiology
Director, Hospital Epidemiology, Occupational Health and Safety Program

William A Rutala, PhD, MS, MPH


Phone: (919) 843-1397
Fax: (919) 966-1451
Email: brutala@unch.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, NC 27599-7030

Education

M.S., University of Tennessee, 1972
M.P.H., School of Public Health, University of North Carolina, 1977
Ph.D., School of Public Health, University of North Carolina, 1979

Board Certifications

Infection Control, 1984, 1994, 1999, 2004, 2009

Clinical Interests

Disinfection, sterilization, cross-infection, healthcare-associated infections, outbreaks, antibiotic-resistant pathogens.

Research Summary

My research interests are the etiology and prevention of healthcare-associated infections with a special focus on disinfection and sterilization of reusable medical and surgical devices (e.g., endoscopes, surgical instruments). Other areas of active research include contribution of the hospital environment to disease transmission, medical waste management, hand hygiene, preventing transmission of infectious agents including multiply-drug resistant organisms, prevention of healthcare-associated Creutzfeldt-Jacob Disease, investigation of healthcare-associated outbreaks, and new and emerging pathogens in healthcare.

Publications

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Rutala CV

Arlene Seña-Soberano, MD, MPH

Associate Professor of Medicine, School of Medicine
Medical Director, Durham County Health Department
Lab Director, Durham County Health Department

Arlene Sena-Soberano


Phone: (919) 966-3289
Fax: (919) 966-6714
Email: arlene_soberano@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., The University of North Carolina School of Medicine, 1992
M.P.H., The University of North Carolina School of Public Health, 1998

Board Certifications

Diplomat, American Board of Internal Medicine in Infectious Diseases
Diplomat, American Board of Internal Medicine

Clinical Interests

Dr. Sena’s research work has mainly focused on surveillance of HIV and sexually transmitted infections (STIs) and clinical trials involving STI diagnostics and treatment. Much of her work has been conducted locally at the Durham County Health Department in Durham, NC. Dr. Sena has a primary interest in Trichomonas vaginalis (CID: 44: 13, 2007) and syphilis (CID 51: 700, 2010). She has also been involved with several public investigations involving emerging infectious diseases in the community (Em Infect Dis 16: 197, 2010; Ped Inf Dis Jour 29: 86, 2010).

Publications

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Sena-Soberano Biosketch

Frederick Sparling, MD

Professor of Medicine Emeritus, School of Medicine
Director, Southeast Regional Center of Excellence for Emerging Infections and Biodefense
Director, NC Sexually Transmitted Diseases Cooperative Research Center

Frederick_SparlingPhone: (919) 843-8598
Fax: (919) 843-1015
Email: zman@med.unc.edu


130 Mason Farm Rd.
Chapel Hill, NC 27599-7031

Education

M.D., Harvard Medical School, 1962

Board Certifications

American Board of Internal Medicine, 1970
Subspecialty Boards of Infectious Disease, American Board of Internal Medicine, 1977

Clinical Interests

Dr Sparling attends regularly on the inpatient consult service but does not see new patients in the clinic

Research Summary

Dr. Sparling is interested in microbial pathogenesis, specifically how gonococci and related bacteria modulate their cell surface to enable infection of humans. This includes production of iron-regulated bacterial receptors for binding human tranferrin and lactoferrin as well as hemoglobin. Using a variety of approaches including molecular genetics, biochemistry, immunology and both animal and human models of infection, the roles of particular bacterial outer membrane proteins in various stages of infection are being delineated. Other efforts are directed at translating knowledge of bacterial surface proteins into a vaccine for gonorrhea, using recombinant proteins, DNA vaccines and viral vectors as well as animal models.

Dr. Sparling is interested in emerging infections and biodefense, and directs a large NIH funded regional center of excellence in biodefense and emerging infections (SERCEB), supporting investigators at many institutions in the SE and elsewhere who work on dengue viruses, alphaviruses, Coronaviruses, Yesinia and tularemia, and innate and adaptive immunity. He also directs another large NIH funded center on sexually transmitted infections (SE STI CRC), the prime focus of which is the pathogenesis and prevention of gonorrhea.

PUBLICATIONS

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Sparling Biosketch

Heidi Swygard, MD, MPH

Clinical Associate Professor of Medicine, School of Medicine

Swygard


Phone: (919) 843-1011
Fax: (919) 966-6714
Email: heidi_swygard@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., Indiana University School of Medicine, 1994
M.P.H., University of North Carolina School of Public Health, 2003

Board Certifications

Diplomat, American Board of Internal Medicine, valid through 2008

Clinical Interests

Public health, epidemiology, sexually transmitted diseases.

Publications

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Swygard Biosketch

David Weber, MD, MPH

Professor of Medicine and Pediatrics, School of Medicine
Professor of Epidemiology, Gillings School of Global Public Health

David J Weber, MD, MPH


Phone: (919) 966-2536
Fax: (919) 966-6714
Email: dweber@unch.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., University of California at San Diego, 1977
M.P.H., School of Public Health, Harvard University, 1985

Board Certifications

National Board of Medical Examiners, 1977
Diplomate, American Board of Internal Medicine, 1980
American Heart Association, Advanced Cardiac Life Support, 1983
American Heart Association, Advanced Cardiac Life Support, Instructor, 1985
Diplomate, Infectious Disease Boards, American Board of Internal Medicine, 1988
Diplomate, Critical Care Medicine Boards, American Board of Internal Medicine, 1991
Diplomate, Preventive Medicine Boards, American Academy of Preventive Medicine, 1992

Research Summary

Hospital-accquired (nosocomial) infections especially antibiotic-resistant pathogens, surveillance, disinfection and sterilization, nosocomial pneumonia, hand hygiene, and outbreak investigations. Other research interests include new and emerging infectious diseases (Pfiesteria, CJD, Norwalk agent), infections in child care centers, tuberculosis, and bioterrorist agents.

Publications

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Weber Biosketch

Becky White, MD, MPH

Clinical Assistant Professor of Medicine School of Medicine Co-Director of HIV Services
North Carolina Department of Corrections, Division of Prisons


Becky White 2012Phone: (919) 843-8602
Fax: (919) 966-6714
Email: bls@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.P.H., UNC Gillings School of Global Public Health, 2008
M.D., University of Virginia Medical School, 1992
Virginia Commonwealth University Health Systems
Fellowship: University of North Carolina Health Sciences Center

Board Certifications

Diplomate, American Board of Internal Medicine, 1995, 2005
Diplomate, American Board of Internal Medicine, Subspeciality of Infectious Diseases, 1999, 2008

Clinical Interests

Treatment and prevention of HIV/STDs in incarcerated persons and African-Americans

Research Summary

Dr. White is an HIV health service researcher and a practicing infectious disease physician. Dr. White uses her "real world" clinical experience to inform her research. Her research focuses on the dynamic interface between public health and medicine. She was one of the leading physician's who described the association between the release of HIV-infected prisoners and the subsequent deleterious effect (increase) on their viral loads. This connection continues to have significant HIV-transmission and health outcome implications for at-risk populations in the community as well as released prisoners. Furthermore, along with others, she conducted the first randomized controlled trial of directly observed antiretroviral therapy vs. self-administered antiretroviral therapy in a state prison system. She also has participated in the implementation of the first ever HIV-opt out screening in the North Carolina state prison system. She is now expanding her research focus on the HIV at risk community and her research interests span from HIV screening/testing to access and adherence to highly active antiretroviral therapy in underserved populations. Her clinical interests include treatment of HIV infection and syphilis. She invites anyone interested in joining her research team to contact her.

Publications

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Becky White Biosketch

David Wohl, MD

Associate Professor of Medicine, School of Medicine
Co-Director of HIV Services, North Carolina Department of Corrections


David_Wohl

Phone: (919) 843-2723
Fax: (919) 966-6714
Email: wohl@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education
M.D., Robert Wood Johnson Medical School, Camden, NJ, 1991 
Residency, Internal Medicine, Duke University Medical Center, 1994
Infectious Diseases Fellowship, UNC-Chapel Hill, 1998

Board Cerfitifactions

Internal Medicine ABIM, 1995-2005
Board Certified Infectious Diseases, 2000

Research Summary

Dr. Wohl’s research interests fall into two major areas: the metabolic complications of HIV and its therapies and the nexus between incarceration and the HIV epidemic.

Publications

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Wohl Biosketch

Sonia Napravnik, PhD

Assistant Research Professor of Medicine,  School of Medicine

Napravnik


Phone: (919) 966-3875
Fax: (919) 966-8928
Email: sonia_napravnik@med.unc.edu

CB# 7215
130 Mason Farm Rd
2101 Bioinformatics Building
Chapel Hill, NC 27599-7215

Education

 

B.A.,University of Western Ontario,1992
B.S.,University of Toronto,1998
M.P.H., University of North Carolina at Chapel Hill, 2000
P.h.D.,  University of North Carolina at Chapel Hill, 2004

Publications

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Napravnik Biosketch

William Goldman, PhD

Professor and Chair, Microbiology and Immunology, School of Medicine

Goldman


Email: wgoldman@email.unc.edu









Education

B.S.,Indiana University,1976
Ph.D., University of North Carolina, Chapel Hill, 1980

Research Interests

Pathogenesis of bacterial and fungal infections of the respiratory tract: histoplasmosis, pneumonic plague, and pertussis.

Research Summary

 

Successful respiratory pathogens must be able to respond swiftly to a wide array of sophisticated defense mechanisms in the mammalian lung. In histoplasmosis, macrophages — a first line of defense in the lower respiratory tract — are effectively parasitized by Histoplasma capsulatum. This process depends on virulence factors produced as this "dimorphic" fungus undergoes a temperature-triggered conversion from a saprophytic mold form to a parasitic yeast form. One such molecule is a calcium-binding protein (CBP) that is secreted preferentially by the yeast form and is essential for Histoplasma virulence. The experiments to unravel CBP structure and function have relied heavily on our development of a telomeric shuttle plasmid that has been used for complementation cloning, gene disruptions, RNA interference, and reporter gene constructs. In addition, random insertional mutagenesis and transcriptional profiling with microarrays are helping us identify and characterize genes involved in the regulation of CBP1 expression.
Another yeast phase-specific product of H. capsulatum is alpha-(1,3)-glucan, a cell wall polysaccharide that is associated with virulence in a variety of fungal pathogens. We have taken two approaches to study alpha-(1,3)-glucan: the first is a forward genetics strategy, using Agrobacterium-mediated insertional mutagenesis, to identify genes implicated in the regulation, synthesis, and processing of this polysaccharide. The second approach uses reverse genetics, combining fungal gene disruption with mammalian RNA-interference, to study the genes involved in production of and response to alpha-(1,3)-glucan. This work has revealed that alpha-(1,3)-glucan on the surface of Histoplasma yeasts masks recognition of the underlying beta-glucan by dectin-1, a macrophage pattern-recognition receptor that is critical in the innate immune response to fungi.
Yersinia pestis also displays two temperature-regulated lifestyles, depending on whether it is colonizing a flea or mammalian host. Inhalation by humans leads to a rapid and overwhelming disease, and we are trying to understand the development of pneumonic plague by studying genes that are activated during the stages of pulmonary colonization. We have developed and characterized a mouse model for studying the pathological and immunological changes during the progression of pneumonic plague. This model system has revealed two sharply contrasting phases to the syndrome: the first phase of infection features rapid bacterial proliferation in the lung, but almost no inflammatory response, symptoms, or pathology; the second phase, starting at approximately 36 hours post-inoculation, is marked by inflammation and pneumonia that lead quickly to death. The utility of this model was highlighted in a study that demonstrated how a plasminogen-activating protease (encoded by the pla gene of Y. pestis) is essential for development of the second phase of this disease. Most of our current work is focused on understanding the bacterial and host mechanisms responsible for controlling these two phases of pneumonic plague.
We are also continuing studies of one of the virulence factors of Bordetella pertussis: tracheal cytotoxin (TCT) is a released fragment of peptidoglycan that causes pulmonary inflammation in pertussis (whooping cough). TCT and endotoxin synergistically trigger respiratory epithelial production of nitric oxide, causing ciliated cell damage that corresponds to the well-known airway cytopathology of pertussis. A variety of host receptor systems have been shown to recognize peptidoglycan fragments, and some – such as the PGRP family – are evolutionarily conserved from flies to mammals. Depending on the relationship between bacteria and host, the results of exposure to TCT can be beneficial or pathological. Our current work is aimed at understanding host responses to TCT that include epithelial defense, cytopathology, and remodeling.

 

Publications

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Goldman Biosketch

Marcia Hobbs, PhD

Research Professor of Medicine and Microbiology Immunology, School of Medicine

Marcia Hobbs 2009


Phone: (919) 966-5050
Email: mmhobbs@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030


Education

Ph.D., University of North Carolina at Chapel Hill, 1993

Research Summary

Our laboratory occupies an unusual niche in the Department of Medicine as a hybrid clinical and research lab. We comprise the Microbiology and Human Challenge Core Laboratories of the UNC Sexually Transmitted Diseases Cooperative Research Center (STD-CRC) providing support and assay development for numerous Infectious Disease research projects within the UNC-CH campus and with outside collaborators. In addition to the Core laboratory facilities, we maintain research programs on the molecular epidemiology of Trichomonas vaginalis infection and the pathogenesis of Neisseria gonorrhoeae.

Publications

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Hobbs Biosketch

Irving Hoffman, PA, MPH

Research Professor, School of Medicine
U.S. Director, UNC Project-Malawi
Director of International Operations, IGHID

Hoffman


Email: irving_hoffman@med.unc.edu









Education

P.A., Duke University, 1981
M.P.H., University of North Carolina, 1994

Research Summary

Global Public Health approaches to HIV and Sexually Transmitted Diseases Treatment and Prevention. Integrated approaches to HIV prevention among people who inject drugs. Malaria vaccine efficacy and surveillance. Development of academic (research, training and care) health centers of excellence in Africa, Asia and Central America. 

Publications

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Hoffman c.v.

James Horton, MD

Clinical Professor of Medicine, Carolinas Medical Center
Charlotte, N.C.


Phone: (704) 446-4490

Myers Park Internal Medicine
1350 South Kings Drive
Charlotte, NC 28207

Publications

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Tim Lane, MD

Professor of Medicine Chief, Internal Medicine Training Program
Moses Cone Hospital, Greensboro, N.C.

Lane


Phone: (336) 832-8062
Fax: (336) 832-8026

CB# 7005
Elm St
Greensboro, NC



Publications

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J. Victor Garcia-Martinez , PhD

Professor of Medicine, School of Medicine

Garcia


Phone: (919)843-9600
Fax: (919) 843-9976
Email: garciama@email.unc.edu

Center for AIDS Research
CB #7042
2044 Genetic Medicine Building
Chapel Hill, NC 27599-7042

Education

Ph.D., Georgetown University, 1984
B.Sc., Instituto Technologico y de Estudios Superiores de Monterrey, 1979

Research Summary

Humanized mice, retrovirology, AIDS, stem cell biology and human gene therapy

Publications

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John L. Foster

Research Assistant Professor
Division of Infectious Diseases, School of Medicine

john foster


Phone: (919) 843-9603
Fax: (919) 966-6870
Email: fosterjl@med.unc.edu

2042 Genetic Medicine Building
120 Mason Farm Road, CB#7042
Chapel Hill, NC  27599-7042


Education

PhD, Biochemistry, West Virginia University, 1977

Research Summary

Nef, Vif, and viral tropism and anti-viral drug development, humanized mouse model, analysis of protein function by fine structure mutational analysis

Publications

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Christopher Hurt, MD

Clinical Assistant Professor, School of Medicine

Christopher Hurt photo


Phone: (919) 966-2789 
Fax: (919) 966-6714
Email: christopher_hurt@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., University of Florida College of Medicine, 2003
Residency in Internal Medicine, Brown University/Rhode Island and The Miriam Hospitals, 2003-06
Fellowship in Infectious Diseases, University of North Carolina Hospitals, 2006-09

Board Certifications

American Board of Internal Medicine, Internal Medicine (through 2016)
American Board of Internal Medicine, Infectious Diseases (through 2019)

Research Interests

Acute HIV infection, transmission of antiretroviral drug resistance, HIV phylogenetics, spatial epidemiology, and substance use’s impact on HIV risk

Publications

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Hurt Biosketch

Stanley M. Lemon, MD

Professor of Medicine, School of Medicine

Stan Lemon Pic - April, 2010
    Phone: 919-843-1848
    Fax: 919-966-6714
    Email: smlemon@med.unc.edu

    Mailing: CB# 7030, Bioinformatics Building
    130 Mason Farm Road, 2nd Floor
    Chapel Hill, North Carolina 27599-7030  
    Office: 8034 Burnett-Womack Clincal Sciences Building

Education

M.D., University of Rochester, 1972

Research Summary

Dr. Lemon's laboratory is interested in the innate immune responses to RNA viruses, and how these viruses have evolved to escape these host defenses. Our research focuses on the molecular pathogenesis of hepatitis C virus (HCV) - related liver diseases, including in particular HCV-associated hepatocellular carcinoma, and the development of effective therapies for hepatitis C.

Publications

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Lemon Biosketch

Joseph Tucker, MD, PhD

Assistant Professor, UNC School of Medicine
Director, UNC Project-China

Joseph Tucker - affiliated facultyEmail: jdtucker@unc.edu

Education

PhD, London School of Hygiene & Tropical Medicine, 2014
M.D., University of North Carolina at Chapel Hill, 2004
M.A., Harvard University, 2010

Research Interests

Syphilis and HIV in China, the implementation of routine integrated syphilis/HIV testing, particularly as they relate to Chinese social structures.

Research Summary

My research examines how China’s tremendous social upheaval has resulted in the resurgence of syphilis and other STDs, and how these same social forces can be marshaled to prevent and control STDs.  Our major ongoing projects focus on SESH (social entrepreneurship for sexual health), the health needs of the African migrant population in Guangzhou, and the social epidemiology of STDs.  I have lived and worked full-time in Guangzhou, the capitol of Guangdong Province, over the past five years.  I speak, read, and write fluent Mandarin Chinese.  I am PI on an NIH Fogarty International Center International Research Scientist Development Award (Career Development Award).  I mentor pre and postgraduate trainees through Fogarty, Fulbright-Fogarty, Fulbright, and Doris Duke programs.

Publications

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Tucker Biosketch


Cornelius (Kees) van Dam, MD

Clinical Assistant Professor of Medicine 
Moses Cone Health System, Greensboro, NC

 

1200 N. Elm Street, Greensboro, NC 27401
336-832-7000

1200 N. Elm Street, Greensboro, NC 27401
(336) 832-7000

 

Education

 

M.D., Medical College of Wisconsin
Residency, University of Utah
ID Fellowship, UNC School of Medicine

 

Board Certifications

American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Infectious Diseases (Board Eligible)

Clinical/Research Summary

HIV, Socioeconomic Risks for HIV Infection, Delivery of Care for Patients with HIV/AIDS, ACTG, FUOs, Nontuberculous Mycobacteria

Ann Dennis, MD

Clinical Assistant Professor of Medicine, School of Medicine

Ann Dennis, MD

Phone: (919) 966-2536
Fax: (919) 966-6714
Email: adennis@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

Education

M.D., University of New Mexico School of Medicine, 2004

Board Certifications

American Board of Internal Medicine, Internal Medicine, 2008
American Board of Internal Medicine, Infectious Diseases, 2010

Research Summary

My research broadly encompasses the clinical and epidemiologic aspects of HIV/AIDS, particularly among minority and immigrant populations.  Ongoing research projects include the evaluation of HIV transmission networks in North Carolina using phylogenetic reconstruction of HIV pol sequences, comparison of social recruitment and HIV transmission networks in Central America, and HIV among immigrant Latinos in North Carolina.  I am also very interested in the application of phylogenetic methods in HIV prevention research and primary HIV infection, late presentation to HIV care, and early testing strategies/ linkage to care among minorities.

Publications

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Dennis Biosketch

Satish Gopal, MD

Clinical Assistant Professor of Medicine, School of Medicine
(Divisions of Hematology-Oncology and Infectious Diseases)

Phone: 265-1-755-056
Fax: 265-1-755-954
Email: gopal@med.unc.edu
UNC Project, Tidziwe Centre
Private Bag A-104
Lilongwe
Malawi

Satish Gopal, MD

Phone: 265-1-755-056
Fax: 265-1-755-954
Email: gopal@med.unc.edu


UNC Project
Tidziwe Centre
Private Bag A-104
Lilongwe, Malawi
Education

M.D., Duke University, 2001
M.P.H., University of North Carolina at Chapel Hill, 2000

Board Certifications

American Board of Internal Medicine, Internal Medicine, 2005
American Board of Pediatrics, Pediatrics, 2005
American Board of Internal Medicine, Infectious Diseases, 2011

Research Summary

I am trained as an infectious disease physician and medical oncologist, and am currently based full-time in Malawi, where I work clinically as one of the only oncologists in the country. My clinical and research interests focus on cancer in sub-Saharan Africa, including HIV-related malignancies. Current research projects include: leading a large US multicenter observational study of HIV-associated lymphoma; establishing one of the first large prospective longitudinal cohorts of lymphoma patients from sub-Saharan Africa in Malawi; collaborating with basic scientists to investigate possible genomic differences between HIV-associated lymphoma which occurs before and after antiretroviral therapy, in order to identify mechanisms of lymphomagenesis and therapeutic targets across these distinct settings. I also work closely with others to study the most prevalent cancers in Malawi, including lymphoma, cervical cancer, breast cancer, and Kaposi sarcoma, to gain biological insights into these tumors as well as to develop treatment strategies having acceptable efficacy, toxicity, and cost, which can be specifically tailored to this challenging setting.

Publications

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Gopal Biosketch

David van Duin, MD, PhD

David van DuinAssociate Professor of Medicine
School of Medicine

Director
Immunocompromised Host Infectious Diseases Section

Phone: (919) 843-2200
Fax: (919) 966-6714
Email: vanduin@med.unc.edu

 

Division of Infectious Diseases 
CB# 7030, Bioinformatics Building 
130 Mason Farm Road, 2nd Floor 
Chapel Hill, North Carolina 27599-7030

Education

M.D., University of Amsterdam, Amsterdam, The Netherlands, 1999 
Residency, Internal Medicine, Jacobi Hospital, Bronx, NY 2003
Infectious Diseases Fellowship, Yale University, 2007
Ph.D., Investigative Medicine, Yale University, 2007

Board Certifications

Internal Medicine, 2003-present
Infectious Diseases, 2005-present

Research Summary

Dr. van Duin's research interests include the study of multi-drug resistant gram-negative bacterial infections, and infections in iatrogenic immunocompromised patients, such as solid organ transplant recipients, and hematopoietic stem cell transplant recipients.

Publications

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David van Duin biosketch

Pearlie Chong, MD

Assistant Clinical Professor of Medicine, School of Medicine

Pearlie ChongPhone: (919) 966-2536
Fax: (919) 966-6714
Email: pearlie_chong@med.unc.edu

Division of Infectious Diseases
CB# 7030, Bioinformatics Building
130 Mason Farm Road, 2nd Floor
Chapel Hill, North Carolina 27599-7030

 

Education

M.D., Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada, 2006
Residency in Internal Medicine, Lehigh Valley Hospital, 2006-09
Fellowship in Infectious Diseases, Georgetown University, 2010-12
Fellowship in Transplant Infectious Diseases, Mayo Clinic, 2012-13

Board Certifications

American Board of Internal Medicine, Internal Medicine (through 2019)
American Board of Internal Medicine, Infectious Diseases (through 2022)

Research Summary

Dr. Chong's research interests include the study of infectious complications in immunocompromised patients, such as solid organ transplant recipients and hematopoietic stem cell transplant recipients.

Publications

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Curriculum Vitae

Pearlie Chong CV

Pearlie Chong Biosketch

Pearlie Chong Biosketch

Jessica Lin, MD

Assistant Clinical Professor of Medicine, School of Medicine 

Jessica LinPhone: 919-843-4385
Fax: 919-966-6714
Email:

Division of Infectious Diseases 
CB# 7030, Bioinformatics Building 
130 Mason Farm Road, 2nd Floor 
Chapel Hill, North Carolina 27599-7030

Education

M.D., Baylor College of Medicine, 2005 

Board Certifications

American Board of Internal Medicine, 2008
Subspecialty Board of Infectious Disease, 2011 

Research Summary

Jessica Lin is an infectious disease clinician-scientist with a primary research interest in malaria. She studies the molecular epidemiology of malaria in Southeast Asia, especially with regards to drug resistant-parasites, relapsing vivax infections, and the parasite transmission stages in human and mosquitoes. These studies use sophisticated genotyping and sequencing methods to better understand how drug resistant malaria develops and spreads and how we can better identify and target relapsing parasites. She works with clinical investigators in Thailand and Cambodia who are documenting emerging trends in multidrug-resistant falciparum malaria. Her group was the first to identify genetic strains of vivax malaria that appear predisposed to relapse. They are following up on this finding by using next generation sequencing techniques to search for the genetic determinants of relapse. Her long-term goal is to work at the interface of clinical and molecular studies to help achieve malaria elimination. At the same time, she is developing skills that will help her build a translational genomics research program for infectious diseases in Asia.

Publications

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Lin Biosketch

Claire Farel, MD, MPH

Clinical Assistant Professor of Medicine, School of Medicine

Medical Director, UNC Infectious Diseases Clinic


Claire FarelPhone: (919) 966-2536

 Fax: (919) 966-6714

 Email: cfarel@med.unc.edu

 

 

Education

M.D., University of North Carolina at Chapel Hill, 2004

Residency in Internal Medicine and Global Health Equity, Brigham and Women’s Hospital, 2008

M.P.H., Harvard University, 2008

Fellowship in Infectious Diseases, Massachusetts General Hospital and Brigham and Women’s Hospital, 2010

 

Board Certifications

American Board of Internal Medicine, Internal Medicine, 2008

American Board of Internal Medicine, Infectious Diseases, 2011

 

Research Summary

HIV prevention and outcomes in vulnerable populations