UNC Has Strong Presence at 5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention

July 22, 2009 -- Faculty and students from UNC presented over 30 abstracts at the 5th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention, which took place July 19-22, 2009 in Cape Town, South Africa.

Based in Geneva, Switzerland, the International AIDS Society (IAS) is the world’s leading independent association of HIV professionals, with over 13,000 members in 188 countries, and the International AIDS Conference and the IAS Conference on HIV Pathogenesis, Treatment and Prevention is the world's largest open scientific conference on HIV/AIDS.

Myron Cohen, MD, UNC Associate Vice Chancellor for Global Health and director of the Institute for Global Health & Infectious Diseases, served on the conference's Scientific Programme Committee and co-chaired the Biomedical Prevention Programme Committee.

The following are the UNC abstracts presented at this year's conference:

Prevalence of Hepatitis B virus (HBV) and occult HBV infections among pregnant women coinfected with human immunodeficiency virus type-1 (HIV-1) in Malawi: The BAN study
C. Chasela[1,2], P. Wall[2], E. Teshale[3], M. Hosseinpour[1], J. Drobeniuc[3], S. Ellington[4], M. Codd[2], W. Powderly[2], G. Tegha[1], C. Chavula[1], D. Kayira[1], P. Fitzpatrick[2], A. Kourtis[4], C. van der Horst[5], The UNC Project BAN Study Team
1UNC Project - Lilongwe, Lilongwe, Malawi, 2University College Dublin, School of Public Health and Epidemiology, Dublin, Ireland, 3U.S. Centers for Disease Control and Prevention, Division of Viral Hepatitis, Atlanta, United States, 4U.S. Centers for Disease Control and Prevention, Division of Reproductive Health, Atlanta, United States, 5University of North Carolina - Chapel Hill, Center for Infectious Diseases, Chapel Hill, United States
Abstract 

Understanding delays in HIV care initiation in the Southeastern US
S. Napravnik1, E.S. Brouwer1, E.B. Quinlivan2, P.A. Leone1, E.M. Foust3, M. Cohen1, A.C. Sena2, C.L. Gay2, L. Hightow-Weidman2, K.B. Patterson2, B. Stalzer2, M. Case2, H. Swygard2, J.J. Eron2
1The University of North Carolina at Chapel Hill, Medicine and Epidemiology, Chapel Hill, United States, 2The University of North Carolina at Chapel Hill, Medicine, Chapel Hill, United States, 3NC Department of Health and Human Services, North Carolina Division of Public Health, Raleigh, United States
Abstract 

Community based early infant testing and treatment: experience from Blantyre, Malawi
A. Dow1, Q. Dube2, C.M. Chirambo2, M. Moore2, R. Heyderman2, A. Van Rie1
1University of North Carolina at Chapel Hill, Epidemiology, Chapel Hill, United States, 2Malawi-Liverpool Wellcome Trust, Blantyre, Malawi
Abstract 

Improving Data for PMTCT programme management
W. Mphatswe1, K. Mate2, B. Bennett2, Z. Luvuno3, J. Reddy1, N. Moodley4, N. Rollins1, P. Barker2,5
1Nelson R Mandela School of Medicine, Paediatrics and Child Health, Durban, South Africa, 2Institute for Healthcare Improvement, Cambridge, United States, 3University of KwaZulu Natal, Durban, South Africa, 4Department of Health, KwaZulu Natal, Pietermaritzburg, South Africa, 5University of North Carolina, Department of Paediatrics, Chapell Hill, United States
Abstract 

Provider assisted HIV partner notification is feasible in Malawi
G. Kamanga1, L. Brown1,2, D. Chiwanda1, P. Jawati1, A. Pettifor2, F. Martinson1, I. Hoffman2
1UNC Project, Lilongwe, Malawi, 2University of North Carolina, Chapel Hill, United States
Abstract 

HIV prevention workshops for street youth in St. Petersburg, Russia
R. Yorick1, E. King2, A. Shaboltas1, E. Finnerty3, A. Lynch3, V. Tripathi3, Y. Batluk1, L. Talikowski1, T. Ornstein3, S. Hanck3
1HealthRight International, St. Petersburg, Russian Federation, 2University of North Carolina, School of Public Health, Chapel Hill, United States, 3HealthRight International, New York, United States
Abstract 

Individual case management for injection drug users on antiretroviral therapy in St. Petersburg, Russia: success without replacement therapy
A. Shaboltas1, R. Skochilov1, Y. Levchenko1, L. Brown2, G. Volkova3, V. Elharrar4, A. Kozlov1, I. Hoffman2
1The Biomedical Center and St.Petersburg State University, St.Petersburg, Russian Federation, 2University of North Carolina, Chapel Hill, United States, 3City AIDS Center, St.Petersburg, Russian Federation, 4NIH, Division of AIDS, Washington DC, United States
Abstract 

Self-disclosure of HIV infection: experiences and wellbeing reported by youth in Kinshasa, Democratic Republic of the Congo (DRC)
E. Taylor1, S. Duvall1, A. Pettifor1, B. Mupenda2, M. Kashosi2, C. Holub3, S. Rennie4, F. Behets1
1UNC Gillings School of Global Public Health, Epidemiology, Chapel Hill, United States, 2School of Public Health University of Kinshasa, Kinshasa, Congo, the Democratic Republic of the, 3UNC Gillings School of Global Public Health, Health Behavior and Health Education, Chapel Hill, United States, 4University of North Carolina -Chapel Hill, Dental Ecology, Chapel Hill, United States
Abstract 

Flucytosine plus high dose fluconazole is superior to high dose fluconazole alone: results of a randomized trial comparing cryptococcal meningits treatments in Malawi
A. Jackson1, J. Nussbaum1,2, D. Namarika1,3, P. Jacob1, J. Kenala1, C. Kenyamba1, J. Jarvis4,5,6, S. Jaffar7, M. Hosseinipour1,8, C. van der Horst8, T. Harrison4
1UNC Project, Lilongwe, Malawi, 2University of California at San Francisco, Division of Infectious Diseases, San Fransisco, United States, 3Kamuzu Central Hospital, Department of Medicine, Lilongwe, Malawi, 4St George's University of London, Division of Infectious Diseases, London, United Kingdom, 5Desmond Tutu HIV Centre, Cape Town, South Africa, 6University of Cape Town, Cape Town, South Africa, 7London School of Hygiene and Tropical Medicine, Department of Epidemiology and Population, London, United Kingdom, 8University of North Carolina, Chapel Hill, United States
Abstract 

A multi-compartment, single and multiple dose pharmacokinetic study of the candidate vaginal microbicide 1% tenofovir gel
J. Schwartz1, R. Rountree2, A. Kashuba3, V. Brache4, M. Creinin5, A. Poindexter6, B. Kearney7
1CONRAD/Eastern Virginia Medical School, Arlington, United States, 2Family Health International, Durham, United States, 3University of North Carolina, School of Pharmacy, Chapel Hill, United States, 4PROFAMILIA, Santo Domingo, Dominican Republic, 5University of Pittsburgh, Pittsburgh, United States, 6Advances in Health, Inc., Houston, United States, 7Gilead Sciences, Foster City, United States
Abstract 

Nurse management is not inferior to doctor management of ARV patients: the CIPRA South Africa randomized trial
R. Wood1, M. Fox2, F. Conradie3, M. Cornell1, M. Dehlinger4, C. Heiberg1, C. Ingram3, P. Ive3, C. Orrell1, R. Panchia3, M. Rassool3, W. Stevens3, H. Truter3, C. van der Horst5, J. Zeinekcer1, J. Mcintyre3, I. Sanne3
1University of Cape Town, Cape Town, South Africa, 2Boston University School of Public Health, Center for International Health and Development, Boston, United States, 3University of the Witwatersrand, Johannesburg, South Africa, 4National Institutes for Allergy and Infectious Diseases, Bethesda, United States, 5University of North Carolina - Chapel Hill, Chapel Hill, United States
Abstract 

Evaluating the benefits of incorporating traditional birth attendants in PMTCT service delivery in Lilongwe semi-urban district
C. Kabondo1, C. Zimba1, E. Kamanga1, G. Hamela1, I. Mofolo1, B. Bulla1, F. Martinson1,2, I. Hoffman2, C. van der Horst2, M. Hosseinipour1,2
1UNC Project, Lilongwe, Malawi, 2University of North Carolina at Chapel Hill, Chapel Hill, United States
Abstract 

Optimization of Abbott m2000 RealTime HIV-1 viral load assay on breastmilk, dried blood spots, seminal plasma, and cerebrospinal fluid
A. Loftis1, R. Kshatriya1, K. McCall-Culbreath2, S. Fiscus1, J. Nelson1
1University of North Carolina at Chapel Hill, Microbiology and Immunology, Chapel Hill, United States, 2University of North Carolina at Chapel Hill, Medicine, Chapel Hill, United States
Abstract 

Evaluation of six years of statewide screening and testing for acute HIV infection in North Carolina
J. Kuruc1, A. Mayo2, L. Sampson3, J. Barnhart3, M. Brinson4, E. Foust3, C. Pilcher5, S. McCoy6, C. Gay1, P. Leone1,7, J. Eron1
1University of North Carolina at Chapel Hill, Medicine, Chapel Hill, United States, 2University of North Carolina at Chapel Hill, Epidemiology, Chapel Hill, United States, 3North Carolina Department of Health and Human Services, Communicable Disease Branch, Raleigh, United States, 4North Carolina State Laboratory of Public Health, Raleigh, United States, 5University of California, San Francisco, United States, 6RTI-International, San Francisco, United States, 7North Carolina Department of Health and Human Services, Epidemiology, Raleigh, United States
Abstract 

Sexually transmitted infection incidence relative to time since care entry in a longitudinal HIV clinical cohort
A.J. Mayo1, S. Napravnik2, B. Stalzer2, E.B. Quinlivan2, J.J. Eron2
1University of North Carolina Gillings School of Global Public Health, Epidemiology, Chapel Hill, United States, 2University of North Carolina, Department of Medicine, Chapel Hill, United States
Abstract 

Clinical endpoints reduced through etravirine use in treatment-experienced, HIV-1-infected patients: pooled 96-week results from the phase III DUET trials
J. Eron1, R. Haubrich2, P. Reiss3, M. Thompson4, R. Weber5, S. Nijs6, J. Witek7
1University of North Carolina, Chapel Hill, NC, United States, 2University of California, San Diego, CA, United States, 3Universiteit van Amsterdam, Amsterdam, Netherlands, 4AIDS Research Consortium of Atlanta, Atlanta, GA, United States, 5University Hospital, Zurich, Switzerland, 6Tibotec BVBA, Mechelen, Belgium, 7Tibotec Inc., Yardley, PA, United States
Abstract

Counseling facilitates women's utilization of CD4 count testing in Lilongwe, Malawi
K.P. Gilles1, E.A. Bobrow2, C. Zimba3, I. Mofolo3, G. Hamela3, A.P. Banda3, P. Khruza3, S. Maman1, F. Martinson3, I. Hoffman1, M. Hosseinipour1,3
1University of North Carolina at Chapel Hill, Chapel Hill, United States, 2Elizabeth Glaser Pediatric AIDS Foundation, Washington, United States, 3University of North Carolina Project - Lilongwe, Lilongwe, Malawi
Abstract 

Childhood sexual abuse history affects HIV primary care utilization
A. Woodruff, S. Napravnik, E.S. Brouwer, B. Stalzer, J.J. Eron
University of North Carolina at Chapel Hill, Center for AIDS Research, Chapel Hill, United States
Abstract 

Good antiretroviral and TB treatment outcomes in a nurse-centered primary health care program for HIV co-infected TB patients
A. Van Rie1, N. Mbonze2, K. Tillerson1, F. Kitenge3, I. Roger1, K. Vanden Driessche2, F. Behets1
1University of North Carolina, Epidemiology, Chapel Hill, United States, 2UNC-DRC, Kinshasa, Congo, the Democratic Republic of the, 3University of Kinshasa, School of Public Health, Kinshasa, Congo, the Democratic Republic of the
Abstract 

Association between intravaginal practices and HIV acquisition in women: individual patient data meta-analysis of cohort studies in sub-Saharan Africa
M.F. Chersich1,2, A. Martin Hilber3, K. Schmidlin3, M. Egger3, S. Francis4, J. Baeten5, J. Brown6, S. Delany-Moretlwe1, R. Hayes4, R. Kaul7, S. Luchters8, N. McGrath4,9, L. Myer10, H. Rees1, M. Temmerman8, A. Van der Straten11, J. Van de Wijgert12, D. Watson-Jones4, M. Zwahlen3, N. Low3
1Reproductive Health and HIV Research Unit, University of the Witwatersrand, Department of Obstetrics and Gynaecology, Johannesburg, South Africa, 2International Centre for Reproductive Health, Mombasa, Kenya, 3Institute of Social & Preventive Medicine, Bern, Switzerland, 4London School of Hygiene & Tropical Medicine, London, United Kingdom, 5University of Washington, Departments of Global Health and Medicine, Seattle, United States, 6University of North Carolina, North Carolina, United States, 7University of Toronto, Toronto, Canada, 8International Centre for Reproductive Health, Gent, Belgium, 9Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Durban, South Africa, 10University of Cape Town, Cape Town, South Africa, 11Women's Global Health Imperative, UCSF, RTI International and Department of Medicine, California, United States, 12Center for Poverty-related Communicable Diseases, Academic Medical Center, Amsterdam, Netherlands
Abstract 

Influence of patient baseline clinical and demographic characteristics on choice of initial antiretroviral therapy regimen: evidence of channeling bias in HIV clinical care
E. Brouwer1,2, S. Napravnik1,2, J. Eron Jr.2
1University of North Carolina Gillings School of Global Public Health, Epidemiology, Chapel Hill, United States, 2University of North Carolina at Chapel Hill, Medicine, Chapel Hill, United States
Abstract 

A nurse-centered primary health care model for HIV care of patients with active tuberculosis: antiretroviral treatment initiation decision making
A. Van Rie1, N. Mbonze2, K. Tillerson1, F. Kitenge3, I. Roger1, K. Vanden Driessche2, F. Behets1
1University of North Carolina, Epidemiology, Chapel Hill, United States, 2UNC-DRC, Kinshasa, Congo, the Democratic Republic of the, 3University of Kinshasa, School of Public Health, Kinshasa, Congo, the Democratic Republic of the
Abstract 

Raltegravir (RAL) intensification does not reduce low-level residual viremia in HIV-1-infected patients on antiretroviral therapy (ART): results from ACTG A5244
R. Gandhi1, S. Zheng2, R. Bosch2, E. Chan2, D. Margolis3, S. Read4, B. Kallungal5, H. Sprenger6, J. Janik6, J. Jacobson7, A. Wiegand8, M. Kearney8, S. Palmer9, J. Coffin10, J. Mellors11, J. Eron3, AIDS Clinical Trials Group A5244 Team
1Massachusetts General Hospital / Harvard Medical School, Boston, United States, 2Harvard School of Public Health, Boston, United States, 3University of North Carolina, Chapel Hill, United States, 4National Instititues of Health, Bethesda, United States, 5Social & Scientific Systems, Inc., Silver Spring, United States, 6Frontier Science Technology and Research Foundation, Amherst, United States, 7Drexel University College of Medicine, Philadelphia, United States, 8National Cancer Institute-Frederick, Frederick, United States, 9Karolinska Institute, Stockholm, Sweden, 10Tufts University, Boston, United States, 11University of Pittsburgh Medical Center, Pittsburgh, United States
Abstract 

Both maternal HAART and daily infant nevirapine (NVP) are effective in reducing HIV-1 transmission during breastfeeding in a randomized trial in Malawi: 28 week results of the Breastfeeding, Antiretroviral and Nutrition (BAN) Study
C. Chasela1, M. Hudgens2, D. Jamieson3, D. Kayira1, M. Hosseinipour1, Y. Ahmed3, G. Tegha1, R. Knight4, A.P. Kourtis3, D. Kamwendo1, I. Hoffman5, S. Ellington3, Z. Kacheche1, J. Wiener3, F. Martinson1, P. Kazembe6, I. Mofolo1, D. Long2, A. Soko1, S.B. Smith2, C. van der Horst7
1UNC Project, Lilongwe, Malawi, 2University of North Carolina, Department of Biostatistics, Chapel Hill, United States, 3U.S. Centers for Disease Control and Prevention, Division of Reproductive Health, Atlanta, United States, 4Principia International, Chapel Hill, United States, 5University of North Carolina, Chapel Hill, United States, 6Kamuzu Central Hospital, Lilongwe, Malawi, 7University of North Carolina, Division of Infectious Diseases, Chapel Hill, United States
Abstract 

Risk of HIV acquisition among men with and without human papillomavirus infection in Kisumu, Kenya
J.S. Smith1, S. Moses2, M. Hudgens1, C.B. Parker3, K. Agot4, I. Maclean2, J.O. Ndinya-Achola5, P.J.F. Snijders6, C.J.L.M. Meijer6, R.C. Bailey7
1University of North Carolina, Chapel Hill, United States, 2University of Manitoba, Winnipeg, Canada, 3Research Triangle Institute, Research Triangle Park, United States, 4UNIM Project, Kisumu, Kenya, 5University of Nairobi, Nairobi, Kenya, 6VU University Medical Center, Amsterdam, Netherlands, 7University of Illinois at Chicago, Chicago, United States
Abstract 

Comparison of gen-probe aptima qualitative HIV-1 RNA to Roche AMPLICOR HIV DNA assays for HIV diagnosis using dried blood spots
S. Fiscus, T. McMillion, M. Schanz, J.T. Hawkins, J. Nelson
University of North Carolina-Chapel Hill, Microbiology & Immunology, Chapel Hill, United States
Abstract 

The sustainability of care beyond HIV prevention trials: an evaluation of the MIRA standard of care programme
K. Clouse1, E.T. Montgomery2, C. Milford3, C. Watadzaushe4, B. Nkala5, N. Lince6, A. van der Straten2
1University of North Carolina Gillings School of Global Public Health, Department of Epidemiology, Chapel Hill, NC, United States, 2RTI International, San Francisco, United States, 3Medical Research Council, Durban, South Africa, 4University of Zimbabwe-UCSF Collaborative Research Programme in Women's Health, Harare, Zimbabwe, 5Perinatal HIV Research Unit, Johannesburg, South Africa, 6Ibis Reproductive Health, Johannesburg, South Africa
Abstract 

HIV partner notification is feasible in sub-Saharan Africa with a high yield of newly diagnosed HIV infection: a pilot study in Lilongwe, Malawi
L. Brown1,2, W. Miller1, G. Kamanga2, C. Nyirenda2, P. Mmodzi2, C. Mapanje2, A. Pettifor1, F. Martinson2, M. Cohen1, I. Hoffman1
1University of North Carolina -Chapel Hill, Chapel Hill, United States, 2UNC Project, Lilongwe, Malawi
Abstract 

High prevalence of cervical squamous intraepithelial lesions in women on antiretroviral therapy in Cameroon: is targeted screening feasible?
J. Atashili1,2,3, A. Adimora3, P. Ndumbe1,2, G. Ikomey2, E. Myers3, J. Eron3, J. Smith3, W. Miller3
1University of Buea, Faculty of Health Sciences, Buea, Cameroon, 2University of Yaounde I, Center for the Study and Control of Communicable Diseases, Yaounde, Yaounde, Cameroon, 3UNC - Chapel Hill, Chapel Hill, United States
Abstract 

Acute HIV study provides improved clinical care, counseling and HIV/AIDS related referral to patients at UNC Project-Kamuzu Central Hospital sexually transmitted infection (STI) clinic in Lilongwe, Malawi
G. Kamanga1, C. Mapanje1, N. Nyirenda1, N. Bonongwe1, B. Ndalama1, S. Phakati1, F. Martinson1, M. McCauley2, C. Gay3, I. Hoffman3, M. Cohen3, For CHAVI 001
1UNC Project, Lilongwe, Malawi, 2Family Health International, Chapel Hill, United States, 3UNC - Chapel Hill, Chapel Hill, United States
Abstract 

Risk factors for incident tuberculosis six months or more after ART initiation -experience from Johannesburg, South Africa
A. Van Rie1, D. Westreich1, I. Sanne2
1UNC-Chapel Hill Epidemiology, Chapel Hill, United States, 2Clinical HIV Research Unit, Department of Medicine, University of the Witwatersrand and Right to Care, Johannesburg, South Africa
Abstract 

Using amphotericin B for the management of cryptococcal meningitis in a resource-limited setting: the role of a printed daily assessment form
D. Namarika1,2, A. Jackson1,2, J. Phulusa1,2, M. Chikasema1,2, C. Kenyemba2, D. Henke2, R. Hogenschurz1, M. Hosseinipour2
1Kamuzu Central Hospital, Department of Medicine, Lilongwe, Malawi, 2UNC Project, Lilongwe, Malawi
Abstract 

ART initiation and increased survival of infants traced from PMTCT to pediatric HIV care: highlighting the need for program coordination in Lilongwe, Malawi
M.M. Kabue1, M. Braun2, L. Aetker2, M. Chirwa2, I. Mofolo2, I. Hoffman2, M. Hosseinipour2, P.N. Kazembe1, M.W. Kline3
1Baylor College of Medicine-Abbott Fund Children's Clinical Centre of Excellence, Lilongwe, Malawi, 2UNC Project, Lilongwe, Malawi, 3Baylor College of Medicine International Pediatric AIDS Initiative (BIPAI), Houston, Texas, United States
Abstract 

Losses to follow-up in 3 Central African country non-PEPFAR ART delivery programs
J. Atibu Losoma1, M. Kiumbu2, I. Azinyue3, H. Mukumbi2, R. Ryder4
1UNC-DRC Project, IeDEA Region 9, Kinshasa, Congo, the Democratic Republic of the, 2Amocongo, Kinshasa, Congo, the Democratic Republic of the, 3IeDEA-Cameroon, Yaounde, Cameroon, 4University of California, San Diego, United States
Abstract 

Challenges in pediatric HIV referral: evidence for PMTCT, infant diagnosis, and pediatric HIV clinic integration in Lilongwe, Malawi
M. Braun1, M. Kabue2, M. Chirwa1, L. Aetker1, P. Chitowe3, M. Eliya3, I. Mofolo1, I. Hoffman1, P. Kazembe2, M. Hosseinipour1
1UNC Project, Lilongwe, Malawi, 2Baylor College of Medicine-Abbott Fund Children's Clinical Centre of Excellence, Lilongwe, Malawi, 3Early Infant Diagnosis Program, Lilongwe, Malawi
Abstract

 

Institute for Global Health & Infectious Diseases contact: Lisa Chensvold, (919) 843-5719, lisa_chensvold@med.unc.edu

Filed under: