Meeting of the SSC Working Group on Coagulation Secondary Standards

Chairman:  Jane Lenahan, US

The annual meeting of this committee was held on 18 July, 2002 with 24 attendees.  

The major topic of the meeting was the need to start arrangements to produce lot 3.  Lot 2 does not expire until 30 June, 2006; however, the use of this product has increased changing the estimated need for a new lot to 2 – 3 years.  Drs. Hubbard and Barrowcliffe will work with the chairman to find potental suppliers, hopefully within a few months

Dr. Hubbard reported on the status (amount and stability) of Lot 2 and Dr. Kitchen reported on a NEQAS survey that included the SSC plasma, lot 2.  Both reports are available by contacting Drs. Hubbard or Kitchen or the chairman.

Drs. Barrowcliffe, Hubbard and Kitchen agreed to generate a short report on calibration, stability and availability of the SSC Secondary Standards to be published in the Journal of Thrombosis and Haemostasis.

Dr. Gray reported that there would be a WHO standard for Factor XI in 2003.

At the Fibrinolysis Subcommittee Meeting on 19, July, Dr. Declerck will discuss the possibility of the fibrinolysis committee carrying out the calibration of tPA and PAI-1.

VWF:CB will be discussed at our next meeting when there should be more information available.

The decision of the committee was that there was not sufficient use of assays for Factors V and XII to warrant having an action item as there is no WHO standard for either of these analytes.