1995 MINUTES
ANIMAL MODELS SUBCOMMITTEE

Saturday, 10 June, 1995, 13:00 - 15:00

Co-Chairs: Gerhard Johnson, USA; Thomas Griggs, USA

The subcommittee meeting was attended by 15 participants.

The group reviewed the project to establish an animal models registry and an electronic bulletin board using the Internet. The Registry of Animal Models of Thrombosis and Hemostasis will be available from "Sunsite" by file transfer protocol (FTP). The subcommittee has established and is operating a "listserv" bulletin board service on Sunsite. Access can be gained by sending a note or message to
Dr. Griggs by: Phone: (919) 966-5207
Fax: (919) 966-1743
E-mail: trg@med.unc.edu
or letter: CB #7075, Division of Cardiology
UNC School of Medicine
Chapel HIll, NC 27599-7075

Recommendation:

The subcommittee voted to make a formal recommendation that the ISTH support this effort by establishing an ISTH "homepage" on the World Wide Web (WWW).

Activities for the coming year:
1. Review and update current entries in the Registry of Animal Models of Thrombosis and Hemostasis.
2. Categorize current and future entries in the registry regarding their utility in assessments of hemostatic components (platelets, fibrin formation, inhibitors, etc.) and thrombotic variables (flow, platelet, endothelial cell function, fibrin formation, fibrinolysis, etc.).
3. To undertake a detailed review of the utility of animal models for assessing therapeutic modalities in the prevention of restenosis following arterial interventions with the goal of establishing guidelines for standardization of animal experimentation in preclinical assessment.